GLP-1 Receptor Agonists

Apr 19, 2026

0

Upload by Hazel

Review of the discovery and development of incretin biology leading to glucagon-like peptide-1 (GLP-1) receptor agonists. Traces the identification of GLP-1 and exendin-4, early clinical advances such as exenatide, and the role of glucose-dependent insulinotropic peptide (GIP). Summarizes mechanisms including insulin secretion, glucagon inhibition, effects on gastric emptying, metabolic and cellular prosurvival pathways, and potential links to gut microbiota and combination therapies for type 2 diabetes and obesity.

Share with

GLP-1 Receptor Agonists

Apr 19, 2026

0

Bookmark

Share

More Options

Fullscreen

This document is user-generated content (UGC). WPS Office is not responsible for its accuracy or copyright. If you believe this content violates your rights, please use the button.