Endovascular Treatment and Microsurgical Clipping for Intracranial Aneurysms - A Comprehensive Comparative Study - treatment outcomes

Q: What was the goal of the comparative study?

To compare clinical profiles, treatment outcomes, and prognostic factors between microsurgical clipping and endovascular treatment for intracranial aneurysms.

Q: How many patients were included, and how were they grouped?

The study analyzed 103 patients: 53 underwent microsurgical clipping and 50 underwent endovascular treatment.

Q: Which approach had a longer mean operative duration?

Microsurgical clipping had a significantly longer mean duration (120.5 ± 30.6 min) than endovascular treatment (68.53 ± 25.23 min).

Q: How were hospital stay and complications different between groups?

Endovascular treatment showed a shorter hospital stay, while postoperative complications were higher in the clipping group, including reported vasospasm and cerebral infarcts.

Sep 30, 2026

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Intracranial aneurysms threaten life because rupture can trigger subarachnoid hemorrhage (SAH) and severe neurologic impairment. This comparative study evaluates microsurgical clipping versus endovascular treatment, focusing on patient profiles, procedural details, treatment outcomes, and prognostic factors. Data from 103 patients treated from January 2018 to December 2023 in North India were analyzed for demographics, aneurysm characteristics, immediate and long-term neurologic status, complications, and statistical predictors using chi-square and t-tests.

LanguageEnglish

CategoryResearch & Report

FormatPDF

Pages7

Reading Time18 min

AccessFree to download

Abstract

Background

Materials and Methods

Results

Conclusion

Introduction

Endovascular treatment

Surgical clipping

Original Article Endovascular Treatment and Microsurgical Clipping for Intracranial Aneurysms: A Comprehensive Comparative Study Abstract Background: Intracranial aneurysms pose significant challenges due to their potential to rupture, leading to subarachnoid hemorrhage (SAH) with severe neurological consequences. Endovascular treatment has emerged as a minimally invasive alternative to surgical clipping, offering distinct advantages in terms of morbidity and recovery. This study aims to compare the clinical profiles, treatment outcomes, and prognostic factors between microsurgical clipping and endovascular treatment in the management of intracranial aneurysms. Materials and Methods: This study analyzed 103 patients treated for intracranial aneurysms at a tertiary care institution in North India between January 2018 and December 2023. Of these, 53 underwent microsurgical clipping and 50 underwent endovascular treatment. Data on demographics, clinical presentations, aneurysm characteristics, and treatment details were meticulously collected. Immediate and long‑term outcomes, including neurological status and complications, were assessed. Statistical analyses, including Chi‑square tests and t‑tests, were used to identify significant predictors of poor outcomes. Results: The mean age was 52.43 years for the clipping group and 54.42 years for the endovascular treatment group, with no significant difference (P = 0.951) . The most common clinical presentations were headache and altered sensorium, with similar frequencies in both groups. Anterior communicating artery aneurysms were the most common location in both cohorts. The mean duration of operation was significantly longer for clipping (120.5 ± 30.6 min) compared to endovascular treatment (68.53 ± 25.23 min, P < 0.001) . Postoperative complications were higher in the clipping group, including vasospasm (22.6% vs. 38.0%, P = 0.090) and cerebral infarcts (22.6% vs. 20.0%, P = 0.741) . Endovascular treatment patients had a shorter hospital stay (18.30 ± 9.40 days vs. 27.55 ± 22.43 days, P = 0.162) . Conclusion: Both endovascular treatment and microsurgical clipping are effective treatment modalities for intracranial aneurysms, each with distinct advantages. Endovascular treatment offers a less invasive approach with shorter hospital stays and potentially better long‑term outcomes. Microsurgical clipping provides durable aneurysm occlusion and remains critical for complex aneurysms. The choice of treatment should be individualized based on aneurysm characteristics, patient condition, and available expertise. Keywords: Endovascular treatment, intracranial aneurysms, microsurgical clipping, prognostic factors, subarachnoid hemorrhage, treatment outcomes Introduction Intracranial aneurysms, defined as abnormal expansions of cerebral blood vessels, posea substantial challenge in neurosurgery due to their potential for rupture, resulting in subarachnoid hemorrhage (SAH) . SAHis a critical condition characterized by bleeding into the subarachnoid space, leading to severe neurological damage anda high risk of mortality. The management of intracranial aneurysms aims to prevent rupture and mitigate associated complications, with two primary treatment modalities at the forefront: endovascular treatment and surgical clipping.[1‑8] This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License (CC BY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. For reprints [contact:](contact: WKHLRPMedknow_reprints@wolterskluwer.com)[ WKHLRPMedknow_reprints@wolterskluwer.com](contact: WKHLRPMedknow_reprints@wolterskluwer.com) Endovascular treatment, introduced in the early 1990s, has revolutionized the management of cerebral aneurysms by providing a minimally invasive alternativ

FAQs

What was the goal of the comparative study?

To compare clinical profiles, treatment outcomes, and prognostic factors between microsurgical clipping and endovascular treatment for intracranial aneurysms.

How many patients were included, and how were they grouped?

The study analyzed 103 patients: 53 underwent microsurgical clipping and 50 underwent endovascular treatment.

Which approach had a longer mean operative duration?

Microsurgical clipping had a significantly longer mean duration (120.5 ± 30.6 min) than endovascular treatment (68.53 ± 25.23 min).

How were hospital stay and complications different between groups?

Endovascular treatment showed a shorter hospital stay, while postoperative complications were higher in the clipping group, including reported vasospasm and cerebral infarcts.

Sep 30, 2026

Upload by CatatanPagi