Drug Information Table - ARBs - Losartan (Cozaar) - Dosage and Safety

Sep 11, 2026

Drug information table for angiotensin II receptor blockers (ARBs) focusing on losartan (Cozaar). Summarizes therapeutic uses including hypertension control, stroke prevention (losartan only), diabetic nephropathy indications (losartan and irbesartan), heart failure treatment (valsartan and candesartan), and migraine prevention (candesartan). Provides administration details such as oral-only use, combination with hydrochlorothiazide, food flexibility, and dose reduction for diuretics or liver failure. Includes adverse effects, contraindications, precautions, interactions, and patient instructions for managing angioedema, monitoring CNS effects, blood pressure, pregnancy risk, hyperkalemia, and drug-level changes.

LanguageEnglish

CategoryGeneral

FormatPDF

Pages1

AccessFree to download

Therapeutic Use

Administration

Side/Adverse Effects

Interventions and Patient Instructions

Contraindications and Precautions

Interactions

FAQs

What conditions is losartan (Cozaar) used to treat or prevent?

Losartan treats hypertension and helps prevent stroke. It is also indicated for diabetic nephropathy, and it may be used in combination with hydrochlorothiazide.

How is losartan administered and what dose considerations apply?

ARBs are available for oral administration only. Losartan may be taken with or without food, and the beginning dose is decreased for patients taking diuretics or with liver failure.

What major adverse effects require specific actions?

Angioedema is a potential risk; treat severe angioedema with IV epinephrine and discontinue any ARB if it occurs. For severe hypotension, monitor blood pressure and manage by expanding volume with IV fluids.

Sep 11, 2026

Upload by Alex Sinclair