Discovery Awards (DISC4) - Pre-submission Informational Webinar - April 28, 2025

Sep 12, 2026

Pre-submission informational webinar materials for CIRM’s Discovery Awards (DISC4), delivered by the CIRM Discovery & Education team. The session explains the program mission, outlines the pre-submission process, and summarizes key program structures and goals. It covers upcoming deadlines for pre-submissions, expected timing for invitations, and follow-up resources including a webinar recording and FAQ. A question-and-answer segment is scheduled for general and program-specific inquiries.

LanguageEnglish

CategoryPresentations

FormatPDF

Pages42

Reading Time15 min

AccessFree to download

Agenda

Part 1: Presentation

Part 2: Question & Answer

Program Overview

Our Mission

CIRM’s Strategic Allocation Framework

CIRM’s Impact Goals

CIRM. CA. GOV Discovery Awards (DISC4) Pre-submission Informational Webinar April 28, 2025 1 CIRM. CA. GOV Quick Announcements • Pre-submissions due June 16, 2025. Invitations expected ~60 days after due date • Webinar recording and FAQ document will be posted in ~1-2 weeks • Q&A will focus on general questions-specific programmatic questions may be directed [to](to discovery@cirm.ca.gov)[ ](to discovery@cirm.ca.gov)[discovery@cirm.ca.gov](to discovery@cirm.ca.gov) 2 CIRM. CA. GOV CIRM's Discovery & Education Team Daisy Xin Science Officer Catherine Schweppe Janie Byrum Ruby Karimjee Science Officer Sr. Science Officer Project Manager Kelly Shepard Chan Lek Tan Uta Grieshammer Director Sr. Science Officer CIRM Fellow 3 CIRM. CA. GOV Webinar Panelists Kelly Shepard Director, Discovery & Education Chan Lek Tan Sr. Science Officer, Discovery & Education Janie Byrum Sr. Science Officer, Discovery & Education Doug Kearney Linda Nevin Associate Director, Senior Science Officer, Grants Management Portfolio Development & Review 4 CIRM. CA. GOV Agenda 1 Part 1: Presentation • Program Overview • Pre-submission Process • Information and Resources 2 Part 2: Question & Answer 3:00-3:30pm 3:30-4:00pm 5 CIRM. CA. GOV Program Overview CIRM. CA. GOV Our Mission Accelerating world class science to deliver transformative regenerative medicine treatments in an equitable manner to a diverse California and world. CIRM. CA. GOV CIRM’s Strategic Allocation Framework The Strategic Allocation Framework (SAF) -Structured and data-driven approach to prioritize resource allocation and provide recommendations to the ICOC for continued implementation of CIRM’s strategic plan 8 CIRM. CA. GOV CIRM’s Impact Goals Accelerating Discovery & Translation 1. Catalyze the identification and validation of at least 4 novel targets and biomarkers, ensuring integration into preclinical or clinical research for diseases in California 2. Accelerate development and utilization of 5-8 technologies that have the potential to improve safety, efficacy, and/or quality of cell and gene therapies Cell & Gene Therapy Approvals 3. Advance 4-7 rare disease projects to BLA 4. Propel 15-20 therapies targeting diseases affecting Californians to late-stage trials Accessibility & Affordability of CIRM-Funded Cell & Gene Therapies 5. Ensure that every BLA-ready program has a strategy for access and affordability Diverse Workforce Development 6. Bolster CIRM's workforce development programs to address gaps and meet evolving demands in regenerative medicine 9 2 GoIlRsM.1CA&. GV Goal 1 | Recommendations (1 of 2) Goal 1-Catalyze the identification and validation of at least 4 novel targets and biomarkers, ensuring integration into preclinical or clinical research for diseases in California Support comprehensive discovery research through DISC4 & DISC5 funding structures ➢ Encourage collaborative, multidisciplinary innovation in stem cell and genetic research across diverse disciplines & disease indications with early engagement of industry to address reproducibility & scalability issues 10

FAQs

When are DISC4 pre-submissions due, and when will invitations be expected?

Pre-submissions are due June 16, 2025. Invitations are expected about 60 days after the due date.

What follow-up materials will be posted after the webinar?

A webinar recording and an FAQ document will be posted in about 1–2 weeks after the session.

What types of questions will the Q&A cover, and how can questions be submitted?

The Q&A will focus on general questions, while program-specific questions can be directed to discovery@cirm.ca.gov.

Sep 12, 2026

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