Trends in incidence and mortality for gynaecological cancers in Southeastern China during 2011-2020: a retrospective analysis of registry data

Sep 21, 2026

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This retrospective, population-based study evaluates changes in incidence and mortality trends of ovarian cancer, cervical cancer, and uterine cancer in Fujian Province, southeastern China, from 2011 to 2020. Registry data include 6,178 new cases and 2,037 deaths among eligible patients. Incidence rates for all three cancers increased over the decade, while uterine cancer mortality remained stable; cervical and ovarian cancer mortality rose. Analyses used age-standardised incidence and mortality rates, including average annual per cent change metrics, and assessed differences across age and perimenopausal groups.

LanguageEnglish

CategoryResearch & Report

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Pages8

Reading Time20 min

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Abstract

Objectives and design

Outcomes and metrics

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Conclusions

Open access Original research Trends in incidence and mortality for gynaecological cancers in Southeastern China during 2011–2020: a retrospective analysis of registry data Linying Liu,1 Yan Zhou,2,3 Jie Lin,1 Ning Xie,1 Haijuan Yu,1 Sufang Deng,1 Yang Sun 1 To cite: Liu L, Zhou Y, Lin J, et al. Trends in incidence and mortality for gynaecological cancers in Southeastern China during 2011–2020: a retrospective analysis of registry data. BMJ Open 2024;14:e083336 . doi:10 . 1136/ bmjopen-2023-083336 ► Prepublication history for this paper is available online. To view these files, please visit the journal online ([https://doi](https://doi). org/10 . 1136/bmjopen-2023- 083336) . Received 18 December 2023 Accepted 10 September 2024 © Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. 1Department of Gynecology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian, China 2Department of Epidemiology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian, China 3Fujian Provincial Office for Cancer Prevention and Control, Fuzhou, China Correspondence to Dr Yang Sun; [sunyang@fjzlhospital.com](sunyang@fjzlhospital.com) ABSTRACT Objectives This study aimed to investigate the changes in the incidence and mortality trends of ovarian cancer (OC), cervical cancer (CC) and uterine cancer (UC) in the Fujian Province, southeastern China. Design Provincial, population-based, retrospective observational study. Setting Fujian province, southeastern China between 2011-2020. Participants From 2011 to 2020, 6178 new cases and 2037 deaths caused by 3 gynaecological cancers were eligible for analysis. Primary and secondary outcome measures The primary outcome measures were the incidence and mortality rates, including the age-standardised incidence rate (ASIR) and age-standardised mortality rate (ASMR), of three gynaecological cancers. The secondary outcome measure was the prevalence (average annual per cent changes (AAPC)) . Results The incidence of all three gynaecological cancers increased from 2011 to 2020. CC had the slowest upward trend, with an AAPC of 2 .54% over the period. However, it had the highest ASIR among the 3 cancersin 2020 (10 .41/100 000) . UC showed a rapid increase, with an AAPC of 15. 15% from 2016 to 2020. While the mortality rate of UC remained stable, both CC and OC also exhibited rising trends, with the CC having the highest ASMR (3 .05/100 000) in 2020. The ASMR for CC increased rapidly, with the highest AAPC of 5.51%. Conversely, changes in the ASMR for UC were not statistically significant (p=0 .601) . Moreover, high incidence rates were more common among perimenopausal women and older participants in the respective cancer groups where the increased mortality was observed. Conclusions Gynaecological cancer burden remains a public health issue in Fujian Province, with an increasing incidence. Improving the healthcare system and promoting a healthy lifestyle should be highlighted to reduce the cancer burden. BACKGROUND Gynaecological cancers significantly impact women’s life and health and their families.1 2 Among these malignancies, cancers of the cervix, uterus and ovaries contribute the STRENGTHS AND LIMITATIONS OF THIS STUDY ⇒ This study examined the burden of gynaecological malignancy in Fujian Province using the latest and most reliable data from the Fujian Cancer Prevention and Control Centre. ⇒ The study covered 5 million people from coastal and inland areas, both developed and developing regions, and rural and urban settings. ⇒ Jointpoint regression was used to analyse epidemiological changes. ⇒ We could not perform an age-period-cohort analysis because of the limitation of 10-year observation. most to the global cancer burden in women.3 Ovarian cancer (OC) is particularly lethal, with app

FAQs

Which gynaecological cancers are analysed in this study?

The study analyses ovarian cancer, cervical cancer, and uterine cancer in Fujian Province.

How many cases and deaths were eligible for the analysis?

Between 2011 and 2020, 6,178 new cases and 2,037 deaths caused by the three gynaecological cancers were eligible for analysis.

What were the major incidence and mortality trends from 2011 to 2020?

Incidence increased for all three cancers. Uterine cancer mortality remained stable, while cervical and ovarian cancer mortality showed rising trends, with cervical cancer having the highest age-standardised mortality rate in 2020.

Sep 21, 2026

Uploaded by Riley