Survival rate of ovarian cancer in Asian countries - a systematic review and metaanalysis

Sep 24, 2026

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Ovarian cancer remains one of the most common cancers affecting women and a leading cause of gynecologic cancer death, driven by delayed diagnosis resulting from limited specific signs and symptoms. This systematic review and meta-analysis evaluates survival rates of ovarian cancer patients across Asian countries to assess current care standards. Studies published through August 2021 were searched in five major databases, quality assessed using the Newcastle-Ottawa tool, and pooled with heterogeneity testing via Cochran-Q and I2.

LanguageEnglish

CategoryResearch & Report

FormatPDF

Pages11

Reading Time28 min

AccessFree to download

Abstract

Background

Methods

Results

Conclusions

Background

Global burden and detection

Incidence and epidemiology patterns

Maleki etal. BMC Cancer (2023) 23:558 BMC Cancer [https://doi.org/10.1186/s12885-023-11041-8](https://doi.org/10.1186/s12885-023-11041-8) RESEARCH Open Access Survival rate of ovarian cancer in Asian countries: a systematic review and metaanalysis Zahra Maleki1†, Mohebat Vali1†, Hossein-Ali Nikbakht2, Soheil Hassanipour3, Aida Kouhi4, Saman Sedighi5, Roya Farokhi6 and Haleh Ghaem7,8* Abstract Background Ovarian cancer is amongst one of the most commonly occurring cancers affecting women, and the leading cause of gynecologic related cancer death. Its poor prognosis and high mortality rates can be attributed to the absence of specific signs and symptoms until advance stages, which frequently leads to late diagnosis. Survival rate of patients diagnosed with ovarian cancer can be used in order to better assess current standard of care; the aim of this study is to evaluate the survival rate of ovarian cancer patients in Asia. Methods Systematic review was performed on articles that were published by the end of August 2021 in five international databases, including Medline / PubMed, ProQuest, Scopus, Web of Knowledge, and Google Scholar. The Newcastle-Ottawa quality evaluation form was used for cohort studies to evaluate the quality of the articles. The Cochran-Q and I2 tests were used to calculate the heterogeneity of the studies. The Meta-regression analysis was also done according to when the study was published. Results A total of 667 articles were reviewed, from which 108 were included in this study because they passed the criteria. Based on a randomized model, the survival rates of ovarian cancer after 1, 3 and 5 years were respectively 73. 65%(95% CI, 68 .66–78. 64), 61 . 31%(95% CI, 55 .39–67. 23) and 59. 60%(95% CI, 56 .06–63. 13) . Additionally, based on meta-regression analysis, there was no relationship between the year of study and survival rate. Conclusions The 1-year survival rate was higher than that of 3-and 5-year for ovarian cancer. This study provides invaluable information that can not only help establish better standard of care for treatment of ovarian cancer, but also assist in development of superior health interventions for prevention and treatment of the disease. †Zahra Maleki and Mohebat Vali contributed equally to this work. *Correspondence: Haleh Ghaem [ghaemh@sums.ac.ir](ghaemh@sums.ac.ir) 1Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran 2Social Determinants of Health Research Center, Health Research Institute, Department of Biostatistics & Epidemiology, School of Public Health, Babol University of Medical Sciences, Babol, Iran 3Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran 4Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA 5Department of Neurosurgery, Keck school of Medicine, University of Southern California, Los Angeles, CA, USA 6Department of Health, Health Systems Research, Health Research Institute, Babol University of Medical Sciences, Babol, Iran 7Non-Communicable Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran 8Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran © The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulati

FAQs

Why is delayed diagnosis important in ovarian cancer outcomes?

Poor prognosis and high mortality are linked to the absence of specific signs and symptoms until advanced stages, which often results in late diagnosis.

How were the included studies selected and assessed?

Articles published through the end of August 2021 were searched in Medline/PubMed, ProQuest, Scopus, Web of Knowledge, and Google Scholar. Cohort study quality was evaluated with the Newcastle-Ottawa form.

What are the pooled survival rates reported for Asian countries?

Based on a randomized model, survival rates after 1, 3, and 5 years were 73.65%, 61.31%, and 59.60%, respectively, with 95% confidence intervals reported for each estimate.

Sep 24, 2026

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