SUBJECTIVE COGNITIVE IMPAIRMENT AND MILD COGNITIVE IMPAIRMENT - Risk Factors in Community-Dwelling Older Adults

Q: What are subjective cognitive impairment (SCD) and mild cognitive impairment (MCI) in this study?

SCD and MCI are preclinical states in the natural history of major neurocognitive disorder or dementia. SCD reflects persistent self-experienced cognitive decline despite normal performance on standardized tests.

Q: Which factors were associated with SCD and MCI?

For SCD, significant risks included age, sex, education, recent life crises, loss of a loved one, cancer, and anxiety diagnosis. For MCI, presenting SCD and a previous depression diagnosis increased risk, while lack of memory complaints was protective.

Sep 29, 2026

Upload by Maya Linwood

Study examines subjective cognitive impairment (SCD) and mild cognitive impairment (MCI) in community-dwelling older adults to identify prevalence and risk factors in Guadalajara, Mexico. Trained gerontologists conducted face-to-face interviews and assessed global cognition using MMSE, meta-memory, and sociodemographic, physical, and mental health variables. SPSS v28 analysis computed odds ratios with 95% confidence intervals. Among 1190 participants, 72.1% had SCD, 11.6% MCI, and 18.1% normal cognition.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages1

Reading Time3 min

AccessFree to download

Introduction

Objective

Method

Results

Conclusions

674 Innovation in Aging, 2025, Vol. 9, No. S2 n = 1190 older adults (from 2018-2024) . Mean age 71.44 years(SD = 7.5), education 9.24 years(SD = 4.8), 78% women(n=927), 53% without a partner. After informed consent, trained gerontologists administered face-to-face interviews, measures of global cognitive functioning with the MMSE, meta-memory, and measurements of risk variables: sociodemographic data, physical and mental health. Data were analyzed with SPSSv28 and Odds Ratios (95% CI) were calculated. Results: Of the total participants 72.1% presented SCD, 11.6% MCI and 18.1% had normal cognitive functioning. The significant risk factors for SCD were age(OR = 1.31,CI=1.09-1.72,p=.025), sex(OR = 2.05, CI = 1.54–2.73, p < .001), education(OR=1.21, CI=1.03–1.53, p = .049), recent life crises(OR = 1.55, CI = 1.16–2.08, p = .002), loss of a lovedone(OR = 1.32, IC = 1.02–1.74, p = .023), cancer(OR = 2.46 CI = 1.40–4.34, p < .001) and anxiety diagnosis(OR = 1.27, CI =1.02–1.71, p = .049). The risk factors for MCI were presenting SCD(OR=1.60, CI=1.48–1.74, p< .001), having a previous diagnosis of depression(OR=1.54, CI=1.10–2.30, p = .016), while having no memory complaints was a protective factor(OR=.622, CI = .432-.895, p = .007). Conclusions: Detection of subjective cognitive impairment as an early manifestation of cognitive pathology is relevant to prevent or delay progression to MCI and dementia, allowing planning interventions to reverse/reduce the rate of conversion and its consequences on people’s lives and public health. Abstract citation ID: igaf122.2299 SUBJECTIVE COGNITIVE IMPAIRMENT AND MILD COGNITIVE IMPAIRMENT: RISK FACTORS IN COMMUNITY-DWELLING OLDER ADULTS Neyda Mendoza Ruvalcaba1, Melina Rodríguez-Díaz2, and Karla Patricia Vazquez-Nuñez2, 1. Universidad de Guadalajara, Guadalajara, Jalisco, Mexico, 2. Universidad de Guadalajara, Tonala, Jalisco, Mexico Introduction: Subjective cognitive impairment (SCD) and mild cognitive impairment (MCI) are preclinical states in the natural history of Major Neurocognitive Disorder or dementia. SCD has been studied as an indicator of MCI and future dementia, it is defined as persistent self-experienced decline in cognitive ability despite having normal performance on standardized tests. Objective: To identify the prevalence and risk factors for SCD and MCI in community-dwelling older adults from the Metropolitan Area in Guadalajara, Mexico. Method: Cross-sectional study, participated

FAQs

What are subjective cognitive impairment (SCD) and mild cognitive impairment (MCI) in this study?

SCD and MCI are preclinical states in the natural history of major neurocognitive disorder or dementia. SCD reflects persistent self-experienced cognitive decline despite normal performance on standardized tests.

How was cognitive status and risk data collected from participants?

After informed consent, trained gerontologists administered face-to-face interviews. Global cognitive functioning was measured with MMSE and meta-memory, alongside sociodemographic, physical, and mental health measures.

Which factors were associated with SCD and MCI?

For SCD, significant risks included age, sex, education, recent life crises, loss of a loved one, cancer, and anxiety diagnosis. For MCI, presenting SCD and a previous depression diagnosis increased risk, while lack of memory complaints was protective.

Sep 29, 2026

Upload by Maya Linwood