Revisiting the standards of cancer detection and therapy alongside their comparison to modern methods

Sep 22, 2026

Upload by Liam

Cancer continues to be a leading fatal disease, with rising global incidence and mortality emphasized by World Health Organization data. Diagnosis typically starts with patient medical history, followed by basic blood tests and imaging to locate suspected cancer and schedule needle biopsy, where timely diagnosis reduces costs and hospitalization. The paper highlights emerging detection options including liquid biopsy, elastography, synthetic biosensors, fluorescence imaging, and reflectance confocal microscopy, while noting limitations of conventional therapy. It compares conventional and modern approaches and discusses future directions.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages22

Reading Time55 min

AccessFree to download

Introduction

Abstract

Key Words

Core Tip

Citation

| W | J | M | World Journal of
Methodology | | --- | --- | --- | --- | Submit a Manuscript: [https://www.f6publishing.com](https://www.f6publishing.com) World J Methodol 2024 June 20; 14(2): 92982 DOI: 10.5662/wjm.v14.i2.92982 ISSN 2222-0682 (online) REVIEW Revisiting the standards of cancer detection and therapy alongside their comparison to modern methods Piotr Gromek, Zuzanna Senkowska, Elżbieta Płuciennik, Zbigniew Pasieka, Lin-Yong Zhao, Adrianna Gielecińska, Mateusz Kciuk, Karol Kłosiński, Żaneta Kałuzińska-Kołat, Damian Kołat Specialty type: Medical laboratory technology Provenance and peer review: Invited article; Externally peer reviewed. Peer-review model: Single blind Peer-review report’s classification Scientific Quality: Grade C Novelty: Grade C Creativity or Innovation: Grade C Scientific Significance: Grade B P-Reviewer: Liu TF, China Received: February 14, 2024 Revised: April 15, 2024 Accepted: April 28, 2024 Published online: June 20, 2024 Processing time: 120 Days and 11.1 Hours Piotr Gromek, Zuzanna Senkowska, Elżbieta Płuciennik, Żaneta Kałuzińska-Kołat, Damian Kołat, Department of Functional Genomics, Medical University of Lodz, Lodz 90-752, Lodzkie, Poland Zbigniew Pasieka, Karol Kłosiński, Żaneta Kałuzińska-Kołat, Damian Kołat, Department of Biomedicine and Experimental Surgery, Medical University of Lodz, Lodz 90-136, Lodzkie, Poland Lin-Yong Zhao, Department of General Surgery & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China Lin-Yong Zhao, Gastric Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China Adrianna Gielecińska, Mateusz Kciuk, Department of Molecular Biotechnology and Genetics, University of Lodz, Lodz 90-237, Lodzkie, Poland Adrianna Gielecińska, Doctoral School of Exact and Natural Sciences, University of Lodz, Lodz 90-237, Lodzkie, Poland Corresponding author: Damian Kołat, BSc, MSc, Research Assistant, Teaching Assistant, Department of Functional Genomics, Medical University of Lodz, Żeligowskiego 7/9, Lodz 90- 752, Lodzkie, [Poland.](Poland. damian.kolat@umed.lodz.pl)[ damian.kolat@umed.lodz.pl](Poland. damian.kolat@umed.lodz.pl) Abstract In accordance with the World Health Organization data, cancer remains at the forefront of fatal diseases. An upward trend in cancer incidence and mortality has been observed globally, emphasizing that efforts in developing detection and treatment methods should continue. The diagnostic path typically begins with learning the medical history of a patient; this is followed by basic blood tests and imaging tests to indicate where cancer may be located to schedule a needle biopsy. Prompt initiation of diagnosis is crucial since delayed cancer detection entails higher costs of treatment and hospitalization. Thus, there is a need for novel cancer detection methods such as liquid biopsy, elastography, synthetic biosensors, fluorescence imaging, and reflectance confocal microscopy. Conventional therapeutic methods, although still common in clinical practice, pose many limitations and are unsatisfactory. Nowadays, there is a dynamic advancement of WJM [https://www.wjgnet.com](https://www.wjgnet.com) 1 June 20, 2024 Volume 14 Issue 2 Gromek P et al. Cancer detection/therapy: Conventional and modern methods clinical research and the development of more precise and effective methods such as oncolytic virotherapy, exosome-based therapy, nanotechnology, dendritic cells, chimeric antigen receptors, immune checkpoint inhibitors, natural product-based therapy, tumor-treating fields, and photodynamic therapy. The present paper compares available data on conventional and modern methods of cancer detection and therapy to facilitate an understanding of this rapidly advancing field and its future direct

FAQs

Why is timely cancer diagnosis emphasized in this paper?

Delayed detection increases treatment costs and hospitalization, while prompt diagnosis supports more effective management. The diagnostic workflow relies on history, blood tests, imaging, and needle biopsy scheduling.

What novel cancer detection methods are discussed?

The paper mentions liquid biopsy, elastography, synthetic biosensors, fluorescence imaging, and reflectance confocal microscopy as emerging detection strategies.

How does the paper evaluate conventional versus modern cancer therapy approaches?

Conventional therapies remain common but have many limitations. Modern methods advance clinical possibilities yet still have drawbacks, so new strategies are needed to improve sensitivity, specificity, safety, and efficacy.

Sep 22, 2026

Upload by Liam