Retraction - Retraction Notice - Diagnostic and Prognostic Utility of High-Sensitivity Troponin T (hs-TNT) and HEART Score

Sep 30, 2026

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Retraction notice for the Cureus article “Diagnostic and Prognostic Utility of High-Sensitivity Troponin T (hs-TNT) and HEART Score in Risk Stratification of Acute Chest Pain in the Emergency Department.” The Editor-in-Chief withdrew the paper due to serious concerns about data reliability and integrity, including internally inconsistent primary outcome counts (30-day vs 45-day MACE) across abstract versus results, tables, and figures. The notice also cites fundamentally flawed statistical analyses using circular modeling that double-counts troponin via its combination with the HEART score, invalidating reported predictive performance and conclusions. Authors agreed with the retraction decision.

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Retraction Notice

Publication and retraction dates

Reasons for retraction

Citation information

Retraction DOI: 10.7759/cureus. r215 Retracted: Diagnostic and Prognostic Utility of High-Sensitivity Troponin T ( hs-TNT) and HEART Score in Risk Stratification of Acute Chest Pain in the Emergency Department Article published 09/18/2025 Retracted 01/06/2026 Muhammad Tayyab 1, Muhammad Farooq 2, Muhammad Subhan Javed Butt 3, 4 , Tamilarasu Gunasekaran 5 , Aisha Bashir 6, Murad Ali 7, Muhammad Arsalan 8 , Muhammad Afnan 9 , Muhammad Irfan Ullah 10 1. Trauma and Orthopaedics, Hayatabad Medical Complex Peshawar, Peshawar, PAK 2. Internal Medicine, Nishtar Medical University, Nishtar-II Hospital, Multan, PAK 3. Emergency Medicine, Royal Lancaster Infirmary, Lancaster, GBR 4. Emergency Medicine, Shifa International Hospital Islamabad, Islamabad, PAK 5. Emergency Medicine, Kampar Hospital, Perak, MYS 6. Internal Medicine, Omar Hospital and Cardiac Centre, Lahore, PAK 7. Internal Medicine, Bacha Khan Medical College, Medical Teaching Institution (MTI) Mardan Medical Complex, Mardan, PAK 8. Internal Medicine, Pakistan Institute of Medical Sciences (PIMS) Hospital, Peshawar, PAK 9. Internal Medicine, Divisional Headquarter Hospital, Kohat, PAK 10. Internal Medicine, Saidu Medical College, Swat, PAK Corresponding author: Murad Ali, [drmurad636@gmail.com](drmurad636@gmail.com) [Corresponding author:](Corresponding author: Murad Ali)[ Murad Ali](Corresponding author: Murad Ali) 1. Trauma and Orthopaedics , Hayatabad Medical Complex Peshawar, Peshawar, PAK 2 . Internal Medicine , Nishtar Medical University, Nishtar-II Hospital, Multan , PAK 3. Emergency Medicine , Royal Lancaster Infirmary, Lancaster, GBR 4 . Emergency Medicine , Shifa International Hospital Islamabad , Islamabad , PAK 5. Emergency Medicine , Kampar Hospital, Perak , MYS 6. Internal Medicine , Omar Hospital and Cardiac Centre , Lahore , PAK 7 . Internal Medicine , Bacha Khan Medical College , Medical Teaching Institution (MTI) Mardan Medical Complex , Mardan , PAK 8. Internal Medicine , Pakistan Institute of Medical Sciences (PIMS) Hospital, Peshawar, PAK 9. Internal Medicine , Divisional Headquarter Hospital, Kohat , PAK 10. Internal Medicine , Saidu Medical College , Swat , PAK How to cite this retraction Tayyab M , Farooq M , Butt M , et al. (January 06 , 2026) Retraction: Diagnostic and Prognostic Utility of High-Sensitivity Troponin T (hs-TNT) and HEART Score in Risk Stratification of Acute Chest Pain in the Emergency Department. Cureus 18(1): r215. doi:10.7759/cureus. r215 Retraction Notice This article has been retracted by the Editor-in-Chief due to serious concerns regarding the reliability and integrity of the reported data and analyses. The article contains internally inconsistent primary outcome counts, with substantially different 30-day and 45-day MACE numbers reported in the abstract compared with the results, tables, and figures, rendering the core findings unreliable. Additionally, the statistical analyses are fundamentally flawed by circular modeling that double-counts troponin through its combination with the HEART score, invalidating the reported predictive performance and conclusions. The authors agree with the decision to retract.

FAQs

When was the article published and when was it retracted?

The article was published on 09/18/2025 and retracted on 01/06/2026.

What key data issue led to the retraction?

Internally inconsistent primary outcome counts were reported, with substantially different 30-day and 45-day MACE numbers in the abstract compared with the results, tables, and figures.

How did the statistical method affect the study’s conclusions?

The statistical analyses were described as fundamentally flawed due to circular modeling that double-counts troponin through its combination with the HEART score, invalidating the reported predictive performance and conclusions.

Sep 30, 2026

Uploaded by Ophelia