Relative Impact of Nucleotide and Copy Number Variation on Gene Expression Phenotypes - read online free

Aug 25, 2026

Relative Impact of Nucleotide and Copy Number Variation on Gene Expression Phenotypes presents research focused on how genetic variants influence gene expression traits. It centers on comparing effects from nucleotide variation and copy number variation, relating genomic differences to measurable phenotypic outcomes. The provided materials include citation and referencing information, online supplemental resources, and bibliographic metadata from Science, situating the work within genetics research and tracking its subsequent scholarly citations.

LanguageEnglish

CategoryResearch & Report

FormatPDF

Pages7

Reading Time18 min

AccessFree to download

References and Notes

Supporting Online Material

Relative Impact of Nucleotide and Copy Number Variation on Gene Expression Phenotypes Barbara E. Stranger, et al. Science 315 , 848 (2007); DOI: 10. 1126/science.1136678 This copy is foryour personal, non-commercial use only. If you wish to distribute this article to others, you can order high-quality copies for your colleagues, clients, or customers by clicking here. Permission to republish or repurpose articles or portions of articles can be obtained by following the guidelines here. [The following resources related to this article are available online at www.sciencemag.org](The following resources related to this article are available online at www.sciencemag.org)[ ](The following resources related to this article are available online at www.sciencemag.org)(this information is current as of April 13, 2010 ): Updated information and services, including high-resolution figures, can be found in the online version of this article at: [http://www.sciencemag.org/cgi/content/full/315/5813/848](http://www.sciencemag.org/cgi/content/full/315/5813/848) [Supporting Online Material](Supporting Online Material can be found at:)[ can be found at:](Supporting Online Material can be found at:) [http://www.sciencemag.org/cgi/content/full/315/5813/848/DC1](http://www.sciencemag.org/cgi/content/full/315/5813/848/DC1) [This article](This article cites 27 articles)[ cites 27 articles](This article cites 27 articles), 7 of which can be accessed for free: [http://www.sciencemag.org/cgi/content/full/315/5813/848\#otherarticles](http://www.sciencemag.org/cgi/content/full/315/5813/848#otherarticles) [This article has been](This article has been cited by 233 article)[ cited by](This article has been cited by 233 article)[ 233 article](This article has been cited by 233 article)([s](s)) on the ISI Web of Science. This article has been cited by 76 articles hosted by HighWire Press; see: [http://www.sciencemag.org/cgi/content/full/315/5813/848\#otherarticles](http://www.sciencemag.org/cgi/content/full/315/5813/848#otherarticles) [This article appears in the following](This article appears in the following subject collections:)[ subject collections](This article appears in the following subject collections:)[:](This article appears in the following subject collections:)[ ](This article appears in the following subject collections:)Genetics [http://www.sciencemag.org/cgi/collection/genetics](http://www.sciencemag.org/cgi/collection/genetics) from www .sc ience mag .org on April 13, 2010 Downloaded Science (print ISSN 0036-8075; online ISSN 1095-9203) is published weekly, except the last week in December, by the American Association for the Advancement of Science, 1200 New York Avenue NW, Washington, DC 20005. Copyright 2007 by the American Association for the Advancement of Science; all rights reserved. The title Science is a registered trademark of AAAS. REPORTS References and Notes 1. J. K. Rose, M. A. Whitt, in Fields ’ Virology, D. M. Knipe, P. M. Howley, Eds. (Lippincott, Williams & Wilkins, Philadelphia, ed. 4, 2001), pp. 1221–1244. 2. B. L. Rao et al., Lancet 364, 869 (2004) . 3. I. Le Blanc et al., Nat. Cell Biol. 7, 653 (2005) . 4. L. H. Luo, Y. Li, R. M. Snyder, R. R. Wagner, Virology 163, 341 (1988) . 5. A. Benmansour et al., J. Virol. 65, 4198 (1991) . 6. S. B. Vandepol, L. Lefrancois, J. J. Holland, Virology 148, 312 (1986) . 7. Y. Gaudin, C. Tuffereau, D. Segretain, M. Knossow, A. Flamand, J. Virol. 65, 4853 (1991) . 8. R. W. Doms, D. S. Keller, A. Helenius, W. E. Balch, J. Cell Biol. 105, 1957 (1987) . 9. Y. Gaudin, Subcell. Biochem. 34, 379 (2000) . 10. Y. Gaudin, R. W. Ruigrok, M. Knossow, A. Flamand, J. Virol. 67, 1365 (1993) . 11. P. Durrer, Y. Gaudin, R. W. Ruigrok, R. Graf, J. Brunner, J. Biol. Chem. 270, 17575 (1995) . 12. B. L. Fredericksen, M. A. Whitt, Virology 217, 49 (1996) . 13. C. C. Pak, A. Puri, R. Blumenthal, Biochemistry 36, 8890 (1997) . 14. F. A.

FAQs

What is the study’s main focus?

The study examines how nucleotide variation and copy number variation jointly affect gene expression phenotypes.

Which journal and publication details are included?

The document lists publication information for Science, including citation formatting and metadata such as DOI.

Where can supporting materials be accessed?

Supporting online material is provided via a linked supplemental content section associated with the article.

Aug 25, 2026

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