Protocol for the Examination of Resection Specimens from Patients with Hepatoblastoma - Version 5.0.0.1 - Reporting and accreditation requirements

Oct 22, 2026

Uploaded by SANS

Protocol for examining resection specimens from patients with hepatoblastoma, specifying which procedure and tumor types are covered and which are excluded (e.g., biopsy and other primary malignant hepatic tumors). Defines CAP Laboratory Accreditation Program requirements, including synoptic reporting rules for core, conditional, and optional data elements, and how diagnostic parameter pairs must be displayed. Provides a reporting template covering case summary sections such as expert consultation, clinical preoperative treatment, specimen procedure, tumor focality, tumor site, tumor size, and histologic type selections.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages23

Reading Time58 min

AccessFree to download

Overview

Scope and exclusions

Version and contributors

Accreditation requirements

Synoptic reporting rules

Summary of changes

Reporting template

Case summary (hepatoblastoma: resection)

Expert consultation

Clinical and specimen sections

Tumor and histology selections

Protocol for the Examination of Resection Specimens from Patients with Hepatoblastoma Version: [5.0.0.1](5.0.0.1) Protocol Posting Date: June 2025 CAP Laboratory Accreditation Program Protocol Required Use Date: June 2024 The changes included in this current protocol version do not affect the prior accreditation date. For accreditation purposes, this protocol should be used for the following procedures AND tumor types: | Procedure | Description | | --- | --- | | Resection | Includes specimens designated lobectomy, segmentectomy, explanted liver, or other | | Tumor Type | Description | | Hepatoblastoma | Includes pediatric hepatoblastoma | The following should NOT be reported using this protocol: | Procedure | | --- | | Biopsy (consider Hepatoblastoma Biopsy protocol) | | Tumor Type | | Other primary malignant hepatic tumors | Version Contributors Cancer Committee Authors: Jessica L. Davis, MD*, Soo-Jin Cho, MD, PhD* Other Expert Contributors: Grace Kim, MD, Sarangarajan Ranganathan, MD, Delores LopezTerrada, MD, PhD, Allison O’Neal, MD, Arun Rangaswami, MD * Denotes primary author. For any questions or comments, contact: [cancerprotocols@cap.org](cancerprotocols@cap.org). Glossary: Author: Expert who is a current member of the Cancer Committee, or an expert designated by the chair of the Cancer Committee. Expert Contributors: Includes members of other CAP committees or external subject matter experts who contribute to the current version of the protocol. Accreditation Requirements Synoptic reporting with core and conditional data elements for designated specimen types* is required for accreditation. • Data elements designated as core must be reported. • Data elements designated as conditional only need to be reported if applicable. • Data elements designated as optional are identified with “+”. Although not required for accreditation, they may be considered for reporting. This protocol is not required for recurrent or metastatic tumors resected at a different time than the primary tumor. This protocol is also not required for pathology reviews performed at a second institution (i.e. , second opinion and referrals to another institution) . Full accreditation requirements can be found on the CAP website under Accreditation Checklists. A list of core and conditional data elements can be found in the Summary of Required Elements under Resources on the CAP Cancer Protocols website. *Includes definitive primary cancer resection and pediatric biopsy tumor types. Synoptic Reporting All core and conditionally required data elements outlined on the surgical case summary from this cancer protocol must be displayed in synoptic report format. Synoptic format is defined as: • Data element: followed by its answer (response), outline format without the paired Data element: Response format is NOT considered synoptic. • The data element should be represented in the report as it is listed in the case summary. The response for any data element may be modified from those listed in the case summary, including“Cannot be determined” if appropriate. • Each diagnostic parameter pair (Data element: Response) is listed on a separate line or in a tabular format to achieve visual separation. The following exceptions are allowed to be listed on one line: o Anatomic site or specimen, laterality, and procedure o Pathologic Stage Classification (pTNM) elements o Negative margins, as long as all negative margins are specifically enumerated where applicable • The synoptic portion of the report can appear in the diagnosis section of the pathology report, atthe end of the report or in a separate section, but all Data element: Responses must be listed together in one location • Organizations and pathologists may choose to list the required elements in any order, use additional methods in order to enhance or achieve visual separation, or add optional items within the synoptic report. The report ma

FAQs

Which resection procedures and tumor types are covered by this protocol?

The protocol covers specimens designated for lobectomy, segmentectomy, explanted liver, or other resections, and includes pediatric hepatoblastoma.

What types should NOT be reported using this hepatoblastoma resection protocol?

Biopsy should not be reported here, and other primary malignant hepatic tumors should not be reported using this protocol.

What are the key synoptic reporting requirements for CAP accreditation?

Core data elements must be reported, conditional elements are reported when applicable, and required Data element: Response pairs must be listed together in synoptic format with visual separation, using defined response wording where needed.

Oct 22, 2026

Uploaded by SANS