Prevention, surveillance, and early detection of hepatocellular carcinoma - a Brazilian multidisciplinary consensus

Sep 22, 2026

Hepatocellular carcinoma is a major cause of cancer-related mortality and a growing public health challenge. The consensus develops multidisciplinary, evidence-based recommendations to support prevention and early detection. It is coordinated by the Brazilian Society of Surgical Oncology with participation from 13 additional national societies, using a steering committee to define key clinical questions across prevention, surveillance, and early detection strategies, and to inform recommendation statements through a tailored evidence review.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages20

Reading Time50 min

AccessFree to download

ARTICLE HIGHLIGHTS

CENTRAL MESSAGE

PERSPECTIVES

ABCD Arq Bras Cir Dig 2026;39:e1947 [https://doi.org/10.1590/0102-672020260000018e1947](https://doi.org/10.1590/0102-672020260000018e1947) POSITION PAPER Prevention, surveillance, and early detection of hepatocellular carcinoma – a Brazilian multidisciplinary consensus VISUAL ABSTRACT | HEPATOCELLULAR CARCINOMA
A BRAZILIAN MULTIDISCIPLINARY CONSENSUS | | | | --- | --- | --- | |
Literature Foundation
Tailored Search for Evidence |
Expert Evaluation
14 Brazilian Societies
43 Specialists |
Consensus
18 Recommendations | | Prevention
|
Surveillance | Early Detection
| AUTHORS Felipe José Fernández COIMBRA , André Luís de GODOY , Paulo Henrique de Sousa FERNANDES , Heládio Feitosa e CASTRO NETO , Rodrigo Nascimento PINHEIRO , Ilka de Fátima Santana Ferreira BOIN , Wellington ANDRAUS , Francisco TUSTUMI , Paulo Cezar Galvãodo AMARAL , Carlos Eduardo BRANDÃO-MELLO , Alexcia Camila BRAUN , Maria Ignez BRAGHIROLI , Luis César BREDT , Carla CAPARROZ , Flair José CARRILHO , Guilherme Moura CUNHA , Alessandro Landskron DINIZ , Daniel Neves FORTE , José Huygens Parente GARCIA , Tércio GENZINI , Mauro Monteiro CORREIA , Cássio Virgílio Cavalcante de OLIVEIRA , Antonio Nocchi KALIL , Agnaldo Soares LIMA , Guilherme Lopes Pinheiro MARTINS , Cristina Melo ROCHA , Marcos Roberto de MENEZES , Joaquim Maurício da MOTTA-LEAL-FILHO , Munir MURAD JÚNIOR , Renata D’Alpino PEIXOTO , Rafael Soares Nunes PINHEIRO , Marcelo Bruno de REZENDE , Héber Salvador de Castro RIBEIRO , Mario Rino MARTINS , Duilio Reis da ROCHA FILHO , Arthur Accioly ROSA , Luiz Arnaldo SZUTAN , Orlando Jorge Martins TORRES , Luiz Augusto Carneiro D’ALBUQUERQUE , Ângelo Alves de MATTOS , Anelisa Kruschewsky COUTINHO , Paulo HERMAN , Alexandre Ferreira OLIVEIRA CORRESPONDENCE Felipe J. F. Coimbra. Email: [felipe.coimbra@accamargo.org.br](felipe.coimbra@accamargo.org.br) HOW TO CITE THIS ARTICLE How to cite this article: Coimbra FJF, Godoy AL, Fernandes PHS, Castro Neto HF, Pinheiro RN, Boin IFSF, et al. Prevention, surveillance, and early detection of hepatocellular carcinoma – a Brazilian multidisciplinary consensus ABCD Arq Bras Cir Dig. 2026;39:e1947. [https://doi](https://doi). org/10.1590/0102-672020260000018e1947 . ARTICLE HIGHLIGHTS • This is the first article in a four-part series of the Brazilian multidisciplinary consensus on hepatocellular carcinoma. • This consensus provides evidence-based recommendations on prevention, surveillance, and early detection. • It integrates the available scientific literature with national clinical expertise to support and guide clinical decision-making. CENTRAL MESSAGE Prevention and early detection save lives in liver cancer. This Brazilian multidisciplinary consensus integrates the best scientific evidence and the expertise of specialists from across the country to more effectively guide the prevention, identification, and surveillance of hepatocellular carcinoma. By answering key clinical questions and offering practical, easy-to-use recommendations, this document helps physicians and healthcare teams provide better care to people at risk. PERSPECTIVES This consensus provides practical guidance to improve the prevention and early detection of liver cancer in daily clinical care. The recommendations emphasize raising awareness of hepatocellular carcinoma, stimulating the development of broader surveillance programs, promoting earlier diagnosis, and improving outcomes for patients at risk for developing primary liver cancer. [instagram.com/revistaabcd/](instagram.com/revistaabcd/) [https://x.com/revista_abcd](https://x.com/revista_abcd) [facebook.com/Revista-ABCD-109005301640367](facebook.com/Revista-ABCD-109005301640367) ABCD Arq Bras Cir Dig 2026;39:e1947 [https://doi.org/10.1590/0102-672020260000018e1947](https://doi.org/10.1590/0102-672020260000018e1947) POSITION PAPER Prevention, surveillance, and early detection of hepatocellular carc

FAQs

What is the central message of the consensus?

Prevention and early detection save lives in liver cancer. The consensus integrates evidence and specialist expertise to guide prevention, identification, and surveillance of hepatocellular carcinoma.

Who coordinated and contributed to the consensus development?

The consensus was coordinated by the Brazilian Society of Surgical Oncology, with participation from 13 additional national societies and a steering committee that defined key clinical questions.

What practical focus do the recommendations emphasize?

The recommendations aim to improve day-to-day clinical care by raising awareness, supporting broader surveillance programs, enabling earlier diagnosis, and improving outcomes for people at risk.

Sep 22, 2026

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