Position paper of the Italian association of medical oncology on health disparities among transgender and gender-diverse people - the Assisi recommendations

Sep 24, 2026

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Transgender and gender-diverse individuals face substantial health disparities across the cancer care continuum. Despite recognized unique healthcare needs, barriers limit access to cancer prevention and treatment services, shaped by disadvantages in key social-economic determinants of health, leading to worse clinical outcomes than in the general population. The Italian Association of Medical Oncology (AIOM) presents the “Assisi Recommendations,” summarizing discussions from an AIOM Oncology Ethics Day and identifying priority actions, including research promotion and new evidence collection, to mitigate disparities and improve health and well-being for all cancer patients.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages11

Reading Time28 min

AccessFree to download

Summary

Introduction

Review Position paper of the Italian association of medical oncology on health disparities among transgender and gender-diverse people: the Assisi recommendations Alberto Giovanni Leone,a,w Raffaella Casolino,b,w Dario Trapani,c,d Rosalba Miceli,e Massimo Massagrande,f Federica Morano,a Nicla La Verde,g Davide Dalu,g Rossana Berardi,h Silvia Marsoni,i Matteo Lambertini,j,k Bianca Iula,l Eva Carieri,m Manlio Converti,n Massimo Di Maio,o,p Giordano Domenico Beretta,q,r Francesco Perrone,s,t Filippo Pietrantonio,a,∗,x and Saverio Cinieri,u,v,x on behalf of the Italian Foundation of Medical Oncology (Fondazione AIOM)Italian Association of Medical Oncology (AIOM) aMedical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G. Venezian 1, Milan 21033, Italy bWolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK cEuropean Institute of Oncology, Istituto di Ricovero e Cura a Carattere Scientiﬁco (IRCCS), Milan, Italy dDepartment of Oncology and Hemato-oncology (DIPO), University of Milan, Milan, Italy eDepartment of Biostatistics for Clinical Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G. Venezian 1, Milan 21033, Italy fELMA Research, Milan, Italy gDepartment of Oncology, Luigi Sacco Hospital, ASST Fatebenefratelli Sacco, Milan, Italy hOncology Clinic, Università Politecnica delle Marche, AOU delle Marche, Ancona, Italy iIFOM -the FIRC Institute of Molecular Oncology, Milan, Italy jDepartment of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genova, Italy kDepartment of Medical Oncology, U. O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genova, Italy lACET - Associazione per la Cultura e l’etica Transgenere (Association for Transgender Culture and Ethics), Milan, Italy. Degree: N/AmIndependent Researcher, Italy. Degree: N/A nAMIGAY Aps-Associazione Italiana Medici e Personale Sanitario, LGBTQIA+ e Friendly (Italian Association of LGBTQIA+ Medical care Providers), Italy oDepartment of Oncology, University of Turin, A. O. Ordine Mauriziano, Turin, Italy pNational Secretary of the Italian Association of Medical Oncology (AIOM), Italy qUOC Oncologia Medica, ASL Pescara P. O., Pescara, Italy rNational President of the Italian Foundation of Medical Oncology (Fondazione AIOM), ItalysClinical Trial Unit, Istituto Nazionale Tumori, IRCCS, Fondazione G. Pascale, Napoli, Italy tPresident-elect of the Italian Association of Medical Oncology (AIOM), Italy uMedical Oncology Unit, Ospedale di Summa A. Perrino, Brindisi, Italy vNational President of the Italian Association of Medical Oncology (AIOM), Italy Summary Transgender and gender-diverse individuals experience substantial health disparities across the cancer care continuum. Despite well recognized unique healthcare needs, there are barriers in accessing cancer prevention and treatment services, inﬂuenced by disadvantages in key social-economic determinants of health which result in worse clinical outcomes, as compared to the general population. The Italian Association of Medical Oncology (AIOM) acknowledges the critical relevance of this issue. The “Assisi Recommendations” here summarize the outcomes of the“AIOM Oncology Ethics Day” dedicated to gender differences in oncology and cancer care of transgender and genderdiverse people. The recommendations generated during a 2-day multidisciplinary discussion address the various aspects of cancer care experience of transgender and gender-diverse people. The promotion of research in this ﬁeld, through the generation of new evidence and the collection of prospective data, has been identiﬁed as a priority action to mitigate these disparities. By acknowledging the challenges of cancer care in transgender and gender-diverse people and recognizing the need for dedicated policy and clinical recommendations, AIOM demonstrates its commitment to improving the health and well-be

FAQs

What health issue does the position paper address?

It addresses health disparities experienced by transgender and gender-diverse people across the cancer care continuum.

Why do disparities occur, according to the paper?

Barriers to prevention and treatment are influenced by disadvantages in key social-economic determinants of health, resulting in worse outcomes than the general population.

What do the “Assisi Recommendations” focus on?

They summarize outcomes from the AIOM Oncology Ethics Day and propose recommendations across multiple aspects of cancer care experience, including prioritizing research and prospective data to mitigate disparities.

Sep 24, 2026

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