Nursing students’ knowledge and attitudes toward human papillomavirus vaccination and infection

Sep 22, 2026

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Human papillomavirus is responsible for a major share of cervical cancers worldwide. This study assessed nursing students’ knowledge and attitudes toward HPV vaccination and infection using a descriptive design and a structured online questionnaire with sociodemographic data and measures of knowledge and attitudes. Results showed low total knowledge on HPV infection and vaccination (36.6% and 45.1%) and negative overall attitudes toward vaccination and infection (27 ± 3.8; 25 ± 1.1). Knowledge correlated positively with attitude, and none of the students reported receiving HPV vaccination. The work recommends educational packages to improve attitudes and understanding.

LanguageEnglish

CategoryResearch & Report

FormatPDF

Pages11

Reading Time28 min

AccessFree to download

Abstract

Introduction

Background and rationale

Methods and measures

Results

Discussion and implications

RESEARCH ARTICLE Nursing students’ knowledge and attitudes toward human papillomavirus vaccination and infection Faten Mabrouk Nouha,b, Hasan Abualruzb, Majdi Al-Zoubib, Khalid Al-Mugheedc, Hanaa Elsayed Ahmed Shahind, Rania Ezzat El-Gobashye,f, A. I. SH. Abdullahb,e, A. M. F. Alassere,f, Jebril Al Hrinatg,h, Aseel Ghaleb Hendii, Eman Saif Soliman Ashoure,j, Nadiah A. Baghdadik, Sally Mohammed Farghaly Abdelaliemk, and Amal Khalifa Khalile aPediatric Nursing, Faculty of Nursing, Menoufia University, Menoufia, Egypt; bFaculty of Nursing, Al-Zaytoonah University of Jordan, Amman, Jordan; cCollege of Pharmacy, Nursing, and Medical Science, Riyadh Elm University, Riyadh, Saudi Arabia; dDepartment of Nursing, College of Applied Medical Sciences, Al-Qurayyat, Jouf University, KSA; eMaternal and Newborn Health Nursing Department, Faculty of Nursing, Menoufia University, Menoufia, Egypt; fFaculty of Nursing, King Salman International University (KSIU), North Sinai, Egypt; gFaculty of Education, Arab American University, Jenin, Palestine; hFaculty of Education, Hebron University, Hebron, Palestine; iIndustrial Engineering Department, The Hashemite University, Amman, Jordan; jFaculty of Nursing, Al Salam University, Al Arabiya, Egypt; kDepartment of Nursing Management and Education, College of Nursing, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia ABSTRACT Human papillomavirus is responsible for 70% cervical cancers worldwide. The study assessed nursing students’ knowledge and attitudes toward human papillomavirus vaccination and infection. A descriptive design was employed among nursing college students between 18 and 25 were selected as a purposive sample for the study. The study was conducted at the Menoufia University-affiliated Faculty of Nursing. A structured online questionnaire including sociodemographic data, level of knowledge about human papillomavirus infection and vaccination, and nursing students’ attitudes toward HPV vaccination. The total knowledge of HPV infection and vaccination was low, 36.6% and 45.1%, respectively. The total attitude toward HPV vaccination was negative mean 27 ± 3.8. The total attitude toward HPV infection was negative mean 25 ± 1.1. Students’ knowledge about HPV infection and vaccination was positively correlated with attitude. None of nursing students not received HPV vaccination. Provide nursing university students with educational packages to improve their attitudes toward the future of the HPV vaccine and to increase their understanding of HPV. ARTICLE HISTORY Received 25 September 2025 Revised 12 December 2025 Accepted 19 December 2025 KEYWORDS Human papillomavirus vaccination; nursing students’ knowledge and attitude Introduction After ovarian and endometrial cancers, cervical cancer ranks third globally among genital tract malignancies, and it is a serious health concern. In terms of mortality, cervical cancer ranks second globally among genital tract malignancies, after ovarian tumors. 1 For Egyptian women aged 15 to 45, cervical cancer ranks as the tenth most common malignant illness.2 Cervical cancer is the 12th most common cause of death for Egyptian women, according to estimates of mortality costs in Egypt.3,4 One of the most substantial diagnosed reasons for cervical cancer is the human papillomavirus.5,6 As types 16, 18, 31, 33, and so on, early proteins 6 and 7 (E6, E7) of high-risk genotypes function as carcinogenic proteins.7 The tumor-suppressor protein P53 is broken down by the E6 protein, which shortens its half-life from many hours to less than 20 min.8,9 To save lifestyles from threatening cervical cancer in Egypt and the local community, it is crucial to recognize the occurrence of excessive-hazard or low-hazard human papilloma virus genotypes. Vaccines for HPV types 16, 18, 11, and 6, in addition to related cervical intraepithelial neoplasia and adenocarcinoma, are endorsed. Regular screening for early intraepithelial lesion

FAQs

How did the study assess nursing students’ knowledge and attitudes toward HPV?

The study used a descriptive design and a structured online questionnaire collecting sociodemographic information plus measures of knowledge about HPV infection and vaccination and students’ attitudes toward HPV vaccination.

What were the key findings on knowledge levels?

Total knowledge about HPV infection and vaccination was low, with 36.6% for infection and 45.1% for vaccination.

Were attitudes toward HPV vaccination and infection positive or negative?

Attitudes were negative overall, with a negative mean score for HPV vaccination (27 ± 3.8) and a negative mean score for HPV infection (25 ± 1.1).

Sep 22, 2026

Upload by Patrick