New Classification of Benign Epithelial Tumors - An Update and Critical Assessment - An Analysis of 678 Consecutive Cases and 1137 Polyps

Q: What was the study objective?

To evaluate colorectal high-risk polyps and synchronized neoplasms/carcinomas according to anatomical localization and demographic characteristics.

Q: How were polyps analyzed and reclassified?

Polypectomy materials from 678 consecutive patients were included, and all epithelial polyps were reclassified using the WHO digestive system tumors classification (2019, 5th edition).

Q: What were the key findings about polyp size and sex distribution?

Males were more common (60.5% vs 39.5%), the mean patient age was 61.1 years, and 86.6% of polyps were smaller than 10 mm.

Sep 24, 2026

Uploaded by Lucas Martin

Objective: evaluate colorectal high-risk polyps and synchronized neoplasms and carcinomas by anatomical localization and demographic characteristics. Methods: 1137 polypectomy materials from 678 consecutive patients diagnosed between July 1, 2018 and July 1, 2022 and undergoing total colonoscopy were analyzed. All epithelial polyps were reclassified using the WHO digestive system tumor classification (2019, 5th edition). Results: males 60.5%, females 39.5%; mean age 61.1±11.1 years; 86.6% of polyps <10 mm.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages6

Reading Time15 min

AccessFree to download

Abstract

Objective

Methods

Results

Conclusions

Introduction

Background and Rationale

Methods and Reclassification

WHO 2019 (5th edition)

Statistical Findings

Demographics and Polyp Characteristics

Conclusions and Clinical Implications

DOI: 10.4274/MMJ.galenos.2023.22755 Medeni Med J 2023;38:39-44 Original Article New Classification of Benign Epithelial Tumors: Colorectal Polyps and Synchronous Neoplasms: An Update and Critical Assessment: An Analysis of 678 Consecutive Cases and 1137 Polyps Benign Epitel Tümörlerin Yeni Sınıflandırması: Kolorektal Polipler ve Senkron Neoplazmlar: Bir Güncelleme ve Kritik Değerlendirme: 678 Ardışık Olgu ve 1137 Polip Analizi Ali KOYUNCUER1, Tulay ZENGINKINET2 1University of Health Sciences Turkey, Umraniye Training and Research Hospital, Clinic of Pathology, Istanbul, Turkey 2 Istanbul Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Clinic of Pathology, Istanbul, Turkey ABSTRACT Objective: We aimed to evaluate of colorectal high-risk polyps and synchronized neoplasms and carcinomas with anatomical localization and demographic characteristics. Methods: Between July 1, 2018 and July 1, 2022, 1137 polypectomy materials of 678 consecutive patients who were diagnosed in the pathology department and underwent total colonoscopy were included in the study. All epithelial polyps were re-classified according to the World Health Organization classification of digestive system tumors-2019, 5th edition. Results: The cases of 60. 5% were male and 39. 5% were female. The mean age of patients with polyps was 61.1 (±11 . 1) years. There was a statistically significant difference between the presence of gender and all epithelial polyps (p=0 . 044) . Epithelial polyps were more common in men than in women (ratio; male/female 1. 58:1) . While the average size of the polyps was 5.2 (±5 . 08) millimeters (mm), 86. 6% of all polyps were smaller than 10 mm. Solitary polyps were observed in 62.5% of all polyps, and multiple polyps were observed in 37.5%. Epithelial polyps constituted 96% of all polyps, and conventional tubular adenoma (69%) was the most common type of polyp. Advanced adenomas (intramucosal adenocarcinomas, polyp cancer) and synchronous adenocarcinomas were found to be 1. 4%(16 polyps) and 0.9%(6 patients) respectively. Polyps were most frequently observed in the sigmoid colon, with a rate of 22.8%, followed by the descending colon and rectum most frequently. There was a significant association between epithelial polyps and anatomical locations (p<0 . 001) . Conclusions: In conventional colorectal adenomas, the frequency of cooccurrence of synchronous neoplasms is higher than in other polyp types. Keywords: Adenoma, dysplasia, intramucosal carcinomas, tubular ÖZ Amaç: Kolorektal yüksek riskli poliplerin ve senkronize neoplazm ve karsinomların anatomik lokalizasyonu ve demografik özellikleri ile değerlendirilmesi amaçlanmıştır. Yöntemler: 1 Temmuz 2018 ile 1 Temmuz 2022 tarihleri arasında patoloji bölümünde tanı konulan ve total kolonoskopisi yapılan 678 ardışık olguya ait 1137 polipektomi materyali çalışmaya dahil edildi. Tüm epitelyal polipler Dünya Sağlık Örgütü sindirim sistemi tümörlerisınıflandırması-2019, 5. baskıya göre yeniden sınıflandırıldı. Bulgular: Çalışmada 678 olgunun %60,5’i erkek, %39,5’i kadındı. Polipli hastaların ortalama yaşı 61,1 idi. Cinsiyet ile tüm epitelyal poliplerin varlığı arasında istatistiksel olarak anlamlı bir fark vardı(p=0,044) . Epitelyal polipler erkeklerde kadınlardan daha yaygındı(oran; erkek/kadın 1,58:1) . Poliplerin ortalama boyutu 5,2 milimetre (mm) iken, tüm poliplerin %86,6’sı 10 mm’den küçüktü. Tümpoliplerin %62,5’inde soliter polipler,%37,5’inde ise multipl poliplergözlendi. Epitelyal polipler tüm poliplerin %96’sını oluşturuyordu ve konvansiyonel tübüler adenom (%69) en yaygın polip tipiydi. İlerlemiş adenomlar (intramukozal adenokarsinomlar, polip kanseri) ve senkronadenokarsinomlar sırasıyla %1,4 (16 polip) ve %0,9 (6 hasta) olarak saptandı. Polipler en sık %22,8 oranıyla sigmoid kolonda görüldü ve bunu en sık inen kolon ile rektum izledi. Epitelyal polipler ile anatomik lokalizasyonlar arasında anlamlı bir ilişki saptandı (p<0,001) . Sonuçlar: Konvansiy

FAQs

What was the study objective?

To evaluate colorectal high-risk polyps and synchronized neoplasms/carcinomas according to anatomical localization and demographic characteristics.

How were polyps analyzed and reclassified?

Polypectomy materials from 678 consecutive patients were included, and all epithelial polyps were reclassified using the WHO digestive system tumors classification (2019, 5th edition).

What were the key findings about polyp size and sex distribution?

Males were more common (60.5% vs 39.5%), the mean patient age was 61.1 years, and 86.6% of polyps were smaller than 10 mm.

Sep 24, 2026

Uploaded by Lucas Martin