Mortality burden of malignant neoplasms of the corpus uteri in Mexico - an analysis of trends from 2000 to 2022

Sep 22, 2026

Upload by Himbo

Temporal trends in malignant neoplasms of the corpus uteri mortality in Mexico from 2000 to 2022 are examined using death certificate data. Age-standardized mortality rate (ASMR) and years of life lost by federal state are estimated, and changes in trends are assessed with joint point regression. The estimated ASMR is 2.5 (95% CI 2.2–2.8), with annual percentage change rising 4.32 between 2000 and 2018. The 60–65 age group shows the highest burden, and findings indicate increasing mortality, supporting policies for early diagnosis and prevention.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages9

Reading Time23 min

AccessFree to download

Introduction

Methods

Results

Conclusion

[www.scielo.br/rbepid](www.scielo.br/rbepid Revista Brasileira de)[ Revista Brasileira de](www.scielo.br/rbepid Revista Brasileira de) Epidemiologia [https://doi.org/10.1590/1980-549720260001](https://doi.org/10.1590/1980-549720260001) ORIGINAL ARTICLE Mortality burden of malignant neoplasms of the corpus uteri in Mexico: an analysis of trends from 2000 to 2022 Carga de mortalidade por neoplasia maligna do corpo do útero no México: uma análise das tendências de 2000 a 2022 Eugenia Flores-AlfaroI , Felipe Adrián Encarnación-LópezII , Gabriela Elizabeth Campos-ViguriIII , Maria Elena Moreno-GodínezII , Ana Karen Herrera-VargasII , Marco Antonio Ramírez-VargasII IUniversidad Autónoma de Guerrero, Facultad de Ciencias Químico-Biológicas, Laboratorio de Investigaciónen Epidemiología Clínica y Molecular – Chilpancingo (GRO), México. II Universidad Autónoma de Guerrero, Facultad de Ciencias Químico-Biológicas, Laboratorio de Toxicología y Salud Ambiental – Chilpancingo (GRO), México. III Unidad Morelos-Instituto Politécnico Nacional, Centro de Investigación en Ciencia Aplicada y Tecnología Avanzada – Cuernavaca, Morelos, México. ABSTRACT | Objective: The aim of this study was to analyze temporal trends in malignant neoplasms of corpus uteri mortality in México from 2000 through 2022. Methods: Certificates of death were analyzed. The age-standardized mortality rate (ASMR), the number of years of life lost, according to the federal state, was estimated. The changes in temporal trends were analyzed using joint point regression. Results: The ASMR from malignant neoplasms of the corpus uteri was estimated at 2.5 (95% confidence interval [CI] 2.2–2. 8), and the annual percentage change from 2000 to 2018 was 4.32. The age group of 60–65 years was most affected. Conclusion: This report indicates an increase in the ASMR from malignant neoplasms of the corpus uteri. It also suggests the need for the development of public health laws focusing on the early diagnosis and prevention of uterine cancer.
Keywords: Endometrial neoplasms. Mortality. Mexico. Uterine neoplasms. | | --- | | CORRESPONDING AUTHOR: Marco Antonio Ramírez-Vargas. Universidad Autónoma de Guerrero, Facultad de Ciencias Químico-Biológicas, Laboratorio de
Toxicología y Salud Ambiental, Av. Lázaro Cárdenas, s/n, 39089, Chilpancingo, GRO, Mé[xico. E-mail: marvarant@gmail.com](xico. E-mail: marvarant@gmail.com); [marco-qbp@hotmail.com](marco-qbp@hotmail.com) | | CONFLICT OF INTERESTS: nothing to declare | | HOW TO CITE THIS ARTICLE: Flores-Alfaro E, Encarnación-López FA, Campos-Viguri GE, Moreno-Godínez ME, Herrera-Vargas AK, Ramírez-Vargas MA. Mortality burden of malignant neoplasms of the corpus uteri in Mexico: an analysis of trends from 2000 to 2022. Rev Bras Epidemiol. 2026; 29: e260001 . [https://doi](https://doi). org/10.1590/1980-549720260001 | | ASSOCIATED EDITOR: Maria Teresa Bustamante Teixeira
SCIENTIFIC EDITORA: Cassia Maria Buchalla | This is an open article distributed under the CC-BY 4.0 license, which allows copying and redistribution of the material in any format and for any purpose as long asthe original authorship and publication credits are maintained. Received on: 09/22/2025 Reviewed on: 10/26/2025 Accepted on: 10/31/2025 Malignant neoplasms of corpus uteri deaths in Mexico: two-decade view. Rev Bras Epidemiol. 2026; 29: e260001 1 [www.scielo.br/rbepid](www.scielo.br/rbepid) [https://doi.org/10.1590/1980-549720260001](https://doi.org/10.1590/1980-549720260001) INTRODUCTION Gynecological cancers are malignant tumors affecting the female reproductive system. These cancers include vaginal, vulvar, cervical, uterine, and ovarian cancer. Gynecological cancer distribution varies according to country, age group, and ethnicity. A global analysis of the annual percentage change (APC) (1990–2021) in gynecological cancers showed that malignant neoplasms of the corpus uteri exhibit an increase (0.45), followed by ovarian cancer (0

FAQs

What is the main objective of the study?

To analyze temporal trends in mortality from malignant neoplasms of the corpus uteri in Mexico from 2000 through 2022.

How were mortality trends analyzed?

Death certificates were analyzed to estimate age-standardized mortality rate (ASMR) and years of life lost by federal state. Joint point regression was used to assess changes in temporal trends.

What did the study find about mortality trends and the most affected age group?

ASMR was estimated at 2.5 (95% CI 2.2–2.8) and the annual percentage change increased (4.32) from 2000 to 2018. The 60–65 years age group was the most affected.

Sep 22, 2026

Upload by Himbo