MistGo - Compared to Conventional Eye Drops - A Patient-Reported Evaluation of Comfort and User-Friendliness in Glaucoma Treatment

Q: What problem does the study address in glaucoma treatment?

The study targets poor adherence caused by difficulties with accurate self-administration and discomfort associated with conventional eye drop bottles.

Q: How was MistGo® compared with conventional dispensers?

Twenty-two patients used MistGo® for 14 days and rated comfort, user-friendliness, and administration confidence on 0–10 scales for both devices.

Q: Did MistGo® improve perceived administration accuracy?

No significant difference was found in perceived accuracy of administration, although MistGo® users reported a lower likelihood of medication being applied outside the eye.

Sep 30, 2026

Upload by SANS

Study evaluates how the novel MistGo® micro-dosing mist device compares with conventional eye drop dispensers for patients managing glaucoma or ocular hypertension. Background addresses adherence barriers driven by inaccurate self-administration and discomfort from standard bottles, including fluid overflow and tip contamination risk. In a 14-day use period with 22 participants, MistGo® is rated higher for comfort, reduces discomfort from excess fluid, and improves user-friendliness, while perceived administration accuracy remains similar. Most patients prefer MistGo®, suggesting potential to lower adherence barriers in long-term glaucoma care.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages12

Reading Time30 min

AccessFree to download

Abstract

Background/Objectives

Methods

Results

Conclusions

Introduction

Glaucoma burden and treatment adherence challenges

Barriers from conventional eye drop bottle use

Article MistGo® Compared to Conventional Eye Drops: A Patient-Reported Evaluation of Comfort and User-Friendliness in Glaucoma Treatment Astrid Dissing Sjö 1, Marie Louise Holm Møller 2, Rune Nørager 2, Nicolai Sjö 3 and Miriam Kolko 1,4,5,6, * Academic Editors: Esther M. Hoffmann and Tina Tzee Ling Wong Received: 1 December 2025 Revised: 13 December 2025 Accepted: 19 December 2025 Published: 22 December 2025 Copyright: © 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license. 1 Department of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark; [astriddissingsjo@gmail.com](astriddissingsjo@gmail.com) 2 Design Psychology APS, 1801 Frederiksberg, Denmark; [marielouise@designpsykologi.dk](marielouise@designpsykologi.dk) (M.L.H.M.); [rune@designpsykologi.dk](rune@designpsykologi.dk) (R.N.) 3 Øjenlæge Nicolai Sjö, 1107 Copenhagen, Denmark; [nicolai.sjo@gmail.com](nicolai.sjo@gmail.com) 4 Your Eye Doctors, Eye Hospital Rungsted Kyst, 2960 Rungsted Kyst, Denmark 5 Department of Ophthalmology Aalborg University Hospital, 9000 Aalborg, Denmark 6 Department of Ophthalmology, Rigshospitalet, 2600 Glostrup, Denmark * [Correspondence: miriamk@sund.ku.dk](Correspondence: miriamk@sund.ku.dk); Tel.: +45-29807667 Abstract Background/Objectives: Poor adherence remains a key challenge in glaucoma management, often due to difficulties with accurate self-administration and discomfort associated with conventional eye drop bottles. MistGo® is a novel dispensing device that delivers precise micro-doses of medication as a fine mist, allowing dosing with a neutral head position. With its ergonomic design, eye rest, and dose release button, MistGo® aims to improve comfort and ease of use. This study compared the user-friendliness, comfort, and administration confidence of MistGo® versus conventional eye drop dispensers in patients using topical ocular hypotensive medications. Methods: Twenty-two patients with glaucoma or ocular hypertension who had used conventional eye drop dispensers for ≥3 months were enrolled. Participants used the MistGo® device for 14 days and subsequently rated comfort, user-friendliness, and administration confidence on 0–10 scales for both their conventional dispensers and the MistGo® device. Results: MistGo® was rated significantly higher than conventional eye drop dispensers in terms of comfort (p < 0.0001), caused less discomfort from excess fluid (p < 0.001), and was perceived as more user-friendly (p < 0.001) . There was no significant difference in the perceived accuracy of administration (p = 0.5); however, participants reported a significantly lower likelihood of medication being applied outside the eye when using MistGo® (p < 0 .001) . Overall, 20 out of 22 patients preferred MistGo® . Conclusions: Patients with glaucoma or ocular hypertension preferred MistGo® over conventional eye drop dispensers as they found it more comfortable and user-friendly. These findings suggest that MistGo® has the potential to reduce barriers to adherence in glaucoma care. Further studies are warranted to evaluate its long-term efficacy and broader applicability. Keywords: ocular hypertension; glaucoma; adherence; drug delivery device; comfort; user-friendliness; eye drops 1. Introduction Glaucoma is the leading cause of irreversible vision loss worldwide, affecting millions of people, particularly older adults [1,2] . While there is no cure, disease progression can be slowed through lifelong use of topical ocular hypotensive medications, such as prostaglandin analogues and beta blockers, often administrated multiple times daily [1,2] . These medications are also commonly prescribed to patients with ocular hypertension (OHT), a condition characterized by elevated intraocular pressure without optic nerve damage, to reduce the risk of deve

FAQs

What problem does the study address in glaucoma treatment?

The study targets poor adherence caused by difficulties with accurate self-administration and discomfort associated with conventional eye drop bottles.

How was MistGo® compared with conventional dispensers?

Twenty-two patients used MistGo® for 14 days and rated comfort, user-friendliness, and administration confidence on 0–10 scales for both devices.

Did MistGo® improve perceived administration accuracy?

No significant difference was found in perceived accuracy of administration, although MistGo® users reported a lower likelihood of medication being applied outside the eye.

Sep 30, 2026

Upload by SANS