Latex-Contaminated Kidney Graft as a Source of Perioperative Anaphylaxis - A Case Report

Sep 30, 2026

Latex allergy is a major driver of perioperative anaphylaxis, yet graft-mediated exposure during solid organ transplantation remains insufficiently characterized. The case describes a 45-year-old man with end-stage renal disease and confirmed latex allergy undergoing kidney transplantation with a graft handled using latex gloves during procurement. After multidisciplinary planning, the graft was repeatedly rinsed to reduce antigen load, the operating room was prepared latex-free, and the anesthesia team heightened readiness for anaphylaxis. Surgery and perioperative recovery were uneventful, without complications.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages4

Reading Time10 min

AccessFree to download

Abstract

Introduction

Case Report

Case Reports in Nephrology and Dialysis | Case Rep Nephrol Dial 2026;16:20–23 | | | --- | --- | | DOI: 10. 1159/000549587
Received: October 17, 2025
Accepted: November 8, 2025
Published online: December 12, 2025 | © 2025 The Author(s) .
Published by S. Karger AG, Basel [www.karger.com/cnd](www.karger.com/cnd) | This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC) ([https://karger.com/Services/OpenAccessLicense](https://karger.com/Services/OpenAccessLicense)). Usage and distribution for commercial purposes requires written permission. Single Case Latex-Contaminated Kidney Graft as a Source of Perioperative Anaphylaxis: A Case Report Elodie Faurea, b Mane Andreassian c Ahmad Mroued Ophélie Le Monnierd Benoit Plauda, b, e, g, h Benjamin Deniau a, b, f, g, h a Department of Anesthesiology, Critical Care and Burn Unit, University Hospital Saint-Louis – Lariboisière, AP-HP, Paris, France; bUFR Medecine, Université de Paris Cité, Paris, France; c Department of Urology, Hôpital Saint-Louis AP-HP, Paris, France; dDepartment of Nephrology-Dialysis-Transplantation, University Hospital Centre of Saint Louis, Paris, France; eINSERM UMR 942 MASCOT, Paris, France; fINSERM UMR 970, Paris Transplant Group, Paris, France; gFHU PROMICE, Paris, France; hINI CRCT Network, Vandœuvre-lés-Nancy, France Keywords Latex allergy · Perioperative anaphylaxis · Kidney transplantation · Graft contamination Abstract Introduction: Latex allergy is a leading cause of perioperative anaphylaxis, yet the risk of graftmediated exposure during solid organ transplantation is poorly characterised. Case Presentation: We report the case of a 45-year-old man with end-stage renal disease and confirmed latex allergy who underwent kidney transplantation with a graft that had been handled with latex gloves during procurement. Following multidisciplinary discussion, the graft was repeatedly rinsed with preservation solution to reduce antigenic load. The operating theatre was prepared as latexfree, and the anaesthesia team implemented enhanced readiness for anaphylaxis. The surgery and perioperative course were uneventful, and the patient was extubated in theatre and transferred to intensive care without complication. Conclusion: This case underscores the potential for graftmediated anaphylaxis due to latex contamination during procurement. Systematic latex avoidance from organ retrieval to implantation, along with communication between procurement and implant teams, is crucial to mitigate risk in sensitised recipients. © 2025 The Author(s) . Published by S. KargerAG, Basel Introduction Latex allergy remains a major concern in perioperative medicine, accounting for up to 14% of anaphylactic reactions during anaesthesia [1, 2]. While the prevalence in the general population is estimated at 1–6%, it may be considerably higher in individuals with Correspondence to: Benjamin Deniau, benjdeniau [gmail.com](gmail.com) Case Reports in Nephrology and Dialysis Case Rep Nephrol Dial 2026;16:20–23 21 | DOI: 10. 1159/000549587 | © 2025 The Author(s) . Published by S. Karger AG, Basel [www.karger.com/cnd](www.karger.com/cnd) | | --- | --- | Faure et al.: Anaphylaxis from Latex-Contaminated Renal Allograft predisposing clinical conditions, such as spina bifida or those requiring repeated urological surgeries, where early-life interventions contribute to the aetiology [1] . Sensitisation typically precedes the development of clinical allergy and anaphylaxis, and latex surgical gloves remain the most common source of exposure [1]. Although many paediatric hospitals have adopted latex-free policies, no regulations mandate latex-free environments in adult hospitals or in the setting of organ procurement [3] . Current perioperative recommendations emphasise strict latex avoidance in sensitised patients [3] . However, in the context of transplantation, the risk of graft-mediat

FAQs

What is the central clinical problem addressed in this case report?

The report focuses on perioperative anaphylaxis potentially triggered by latex contamination of a kidney graft during organ procurement and transplantation.

How was latex exposure risk reduced before and during surgery?

The team repeatedly rinsed the graft with preservation solution, prepared the operating theatre as latex-free, and implemented enhanced readiness for immediate anaphylaxis management.

What was the patient’s perioperative outcome?

The procedure and perioperative course were uneventful, and the patient was extubated in theatre and transferred to intensive care without complications.

Sep 30, 2026

Uploaded by MrHarris58