INTERAGENCY AUTISM COORDINATING COMMITTEE - 2022 - Summary of Advances in Autism Research

Oct 15, 2026

Interagency Autism Coordinating Committee (IACC) 2022 Summary of Advances in Autism Research synthesizes progress across autism research and related federal activities. The report outlines the committee’s federal advisory role in coordinating efforts on autism spectrum disorder and provides a structured overview of selected articles. It presents advances by research domain including screening and diagnosis, biology, genetic and environmental factors, interventions, services and supports, and lifespan outcomes.

LanguageEnglish

CategoryResearch & Report

FormatPDF

Pages62

Reading Time2 h 36 min

AccessFree to download

INTRODUCTION

ARTICLES SELECTED FOR THE 2022 SUMMARY OF ADVANCES

SCREENING AND DIAGNOSIS

Clinician Diagnostic Certainty and the Role of the Autism Diagnostic Observation Schedule in Autism Spectrum Disorder Diagnosis in Young Children

A Data-Driven Approach in an Unbiased Sample Reveals Equivalent Sex Ratio of Autism Spectrum Disorder-Associated Impairment in Early Childhood

Provider and Caregiver Satisfaction with Telehealth Evaluation of Autism Spectrum Disorder in Young Children During the COVID-19 Pandemic

Effectiveness of Screening in Early Intervention Settings to Improve Diagnosis of Autism and Reduce Health Disparities

BIOLOGY

Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD

Quantifying social skill deficits and strengths profiles in autistic youth

Infant Visual Brain Development and Inherited Genetic Liability in Autism

Mapping the time course of overt emotion dysregulation, self-injurious behavior, and aggression in psychiatrically hospitalized autistic youth: A naturalistic study

Predictors of language regression and its association with subsequent communication development in children with autism

GENETIC AND ENVIRONMENTAL FACTORS

Associations Between Pregnancy-Related Predisposing Factors for Offspring Neurodevelopmental Conditions and Parental Genetic Liability to Attention-Deficit/Hyperactivity Disorder, Autism, and Schizophrenia: The Norwegian Mother, Father and Child Cohort Study (MoBa)

INTERVENTIONS

Super responders: Predicting language gains from JASPER among limited language children with autism spectrum disorder

SERVICES AND SUPPORTS

Disparities in Early Intervention Program Participation by Children With Autism Spectrum Disorder in a US Metropolitan Area, 2006 to 2016

Mental health screening in pediatric primary care for children with autism

LIFESPAN

Barriers to healthcare and self-reported adverse outcomes for autistic adults: a cross-sectional study

How do autistic people fare in adult life and can we predict it from childhood?

Associations between co-occurring conditions and age of autism diagnosis: Implications for mental health training and adult autism research

Vocational Outcome

INTERAGENCY AUTISM COORDINATING COMMITTEE 2022 SUMMARY OF ADVANCES in Autism Research NATIONAL AUTISM INTERAGENCY AUTISM COORDINATING COMMITTEE 2022 SUMMARY OF ADVANCES in Autism Research COVER DESIGN NIH Medical Arts Branch COPYRIGHT INFORMATION All material appearing in this report is in the public domain and may be reproduced or copied. A suggested citation follows. SUGGESTED CITATION Interagency Autism Coordinating Committee (IACC). 2022 IACC Summary of Advances in Autism Research. December 2023. Retrieved from the U.S. Department of Health and Human Services Interagency Autism Coordinating Committee website: [https://iacc.hhs.gov/publications/summary-of-advances/2022/](https://iacc.hhs.gov/publications/summary-of-advances/2022/). ii ABOUT THE IACC The Interagency Autism Coordinating Committee (IACC) is a federal advisory committee charged with coordinating federal activities concerning autism spectrum disorder (ASD) and providing advice to the Secretary of Health and Human Services (HHS) on issues related to autism. The Committee was established by Congress under the Children's Health Act of 2000, reconstituted under the Combating Autism Act of 2006, and renewed most recently under the Autism Collaboration, Accountability, Research, Education, and Support (CARES) Act of 2019. Membership of the Committee includes a wide array of federal agencies involved in autism research and services, as well as public stakeholders, including autistic adults, family members of those on the autism spectrum, advocates, service providers, and researchers, who represent a variety of perspectives. The IACC membership is composed to ensure that the Committee is equipped to address the broad range of issues and challenges experienced by individuals and families in the autism community. Under past and present authorizing legislation, the IACC was and is currently required to (1) develop and annually update a strategic plan for autism research,(2) develop and annually update a summary of advances in autism research, and (3) monitor federal activities related to autism. Through these and other activities, the IACC provides guidance to HHS and partners with other federal departments, research and advocacy organizations, and the broader autism community to accelerate research and enhance services with the goal of positively impacting the lives of people on the autism spectrum and their families. *** For more information about the IACC, see [http://www.iacc.hhs.gov](http://www.iacc.hhs.gov). iii TABLE OF CONTENTS INTRODUCTION ........................................................................ VI ARTICLES SELECTED FOR THE 2022 SUMMARY OF ADVANCES ............................ 1 SCREENING AND DIAGNOSIS ........................................................... 3 Clinician Diagnostic Certainty and the Role of the Autism Diagnostic Observation Schedule in Autism Spectrum Disorder Diagnosis in Young Children ........................................ 4 A Data-Driven Approach in an Unbiased Sample Reveals Equivalent Sex Ratio of Autism Spectrum Disorder-Associated Impairment in Early Childhood ............................ 6 Provider and Caregiver Satisfaction with Telehealth Evaluation of Autism Spectrum Disorder in Young Children During the COVID-19 Pandemic ................................................ 7 Effectiveness of Screening in Early Intervention Settings to Improve Diagnosis of Autism and Reduce Health Disparities ........................................................ 9 BIOLOGY ............................................................................. 10 Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD ..................... 11 Quantifying social skill deficits and strengths profiles in autistic youth .......................... 12 Infant Visual Brain Development and Inherited Genetic Liability in Autism .......................

FAQs

What is the purpose of the IACC 2022 Summary of Advances in Autism Research?

It compiles progress in autism research and organizes selected advances across key research areas, supporting coordination of federal activities related to autism spectrum disorder.

Which topics are covered in the 2022 summary?

The report groups selected articles into screening and diagnosis, biology, genetic and environmental factors, interventions, services and supports, and lifespan outcomes.

How does the report connect committee responsibilities to ongoing work in autism research?

The IACC is required to maintain and annually update a strategic plan, develop and annually update a summary of advances, and monitor federal autism-related activities to guide HHS and partners.

Oct 15, 2026

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