Global Challenge Program - Enhanced Health Emergency Prevention, Preparedness, and Response (HEPPR) Approach

Jul 19, 2026

A strategic approach for the Global Challenge Program (GCP) supporting Health Emergency Prevention, Preparedness, and Response (HEPPR) and strengthening health emergency capacities. The framework explains the rationale for establishing GCP for HEPPR, defines the program’s core focus areas—scaling HEPPR capacities, improving equitable access to medical countermeasures, and enhancing response readiness—and outlines implementation, cross-cutting themes, and program management. It also describes data, knowledge and learning, operationalization, and reporting mechanisms.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages35

Reading Time1 h 28 min

Overview of GCP

Why is a GCP for HEPPR needed?

What will the GCP-H do?

What is different about the GCP-H?

How will the GCP-H be implemented?

Cross-cutting themes

Results and Program Management

Data, Knowledge and Learning

Operationalization

Reporting

Annexes

References

Public Disclosure Authorized Public Disclosure Authorized Public Disclosure Authorized Public Disclosure Authorized TABLE OF CONTENTS LIST OF ACRONYMS ................................................................................................................................ iv OVERVIEW OF GCP .................................................................................................................................. v I. Why is a GCP for HEPPR needed?..................................................................................................... 1 II. What will the GCP-H do?.................................................................................................................. 4 GCP-H objectives and focus areas ........................................................................................................ 4 Focus area \# 1: Strengthening and scaling core HEPPR capacities..................................................... 5 Focus area \# 2: Improving equitable access to medical countermeasures (MCMs) ........................... 5 Focus area \# 3: Enhancing health emergency response readiness .................................................... 6 III. What is different about the GCP-H? ................................................................................................. 7 IV. How will the GCP-H be implemented? ........................................................................................... 11 Focus Area \# 1: Strengthening and scaling core HEPPR capacities .................................................. 11 Focus Area \# 2: Improving equitable access to medical countermeasures ...................................... 15 Focus Area \# 3: Enhancing health emergency response readiness .................................................. 18 V. Cross-cutting themes ..................................................................................................................... 20 VI. Results and Program Management ................................................................................................ 21 Data, Knowledge and Learning .......................................................................................................... 22 Operationalization ............................................................................................................................. 23 Reporting .......................................................................................................................................... 23 ANNEXES ............................................................................................................................................... 24 REFERENCES .......................................................................................................................................... 29 LIST OF ACRONYMS AGF: Agriculture and Food Global Practice AMEF: Africa Medical Equipment Facility AMR: Antimicrobial Resistance AVATT: Africa Vaccine Acquisition Task Team BMGF: Bill and Melinda Gates Foundation CAT-DDO: Catastrophe Deferred Drawdown Options CEPI: Coalition for Epidemic Preparedness Innovations CERC: Contingent Emergency Response Components CPRT: Crisis Preparedness and Response Toolkit CSE: Clínica Sagrada Esperança DDO: Deferred Drawdown Options DEC: Development Economics DECDG: Development Economics Data Group DECRG: Development Economics Research Group DFAT: Australian Department of Foreign Affairs and Trade DFI: Development Finance Institution DIME: Development Impact DPO: Development Policy Operation DRC: Democratic Republic of Congo ECOWAS: Economic Community of West African States EIB: European Investment Bank EWS: Early Warning Systems FAO: Food and Agriculture Organization FCV: Fragility, Conflict, and Violence Gavi: The Vaccine Alliance GENPAR: Gender in Preparedness & Response GCP: Global Challenge Program GHS

FAQs

Why is a GCP for HEPPR needed?

It addresses growing risks from pandemics and epidemics that can reverse economic and social progress. The document frames the need around strengthening preparedness and response to outbreaks.

What focus areas guide the GCP-H?

The approach centers on three focus areas: strengthening and scaling core HEPPR capacities, improving equitable access to medical countermeasures, and enhancing health emergency response readiness.

How will the GCP-H be implemented and managed?

Implementation is organized around the same three focus areas, and program management covers results, data, knowledge and learning, operationalization, and reporting. The document also includes cross-cutting themes and annexes for supporting detail.

Jul 19, 2026

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