Genomic history of the seventh pandemic of cholera in Latin America and Africa

Sep 14, 2026

Uploaded by Jake

This document details the genomic history of the seventh pandemic of cholera, focusing on its spread in Latin America and Africa. It presents research conducted by a collaborative effort including the University of St Andrews, the Wellcome Sanger Institute, and the London School of Hygiene & Tropical Medicine. The study utilizes whole genome sequencing (WGS) single nucleotide polymorphisms (SNPs) to construct phylogenetic trees, illustrating the relationships between different isolates of Vibrio cholerae. It highlights the concept of 'phylogeography' and discusses the global spread of the seventh pandemic. The document references key institutions and individuals involved in this research, including NR Thomson, François-Xavier Weill, and others from the Global Task Force for Cholera Control. The aim of the research is to understand the relationships between various cholera isolates through genetic analysis. The document also touches upon the distinction between cholera the disease and Vibrio cholerae the bacterium.

LanguageEnglish

CategoryResearch & Report

FormatPDF

Pages21

Reading Time53 min

AccessFree to download

Cholera vs Vibrio cholerae

Vibrio cholerae phylogeny

Global spread of the 7th pandemic

FAQs

What is the main focus of this document?

This document focuses on the genomic history of the seventh pandemic of cholera, particularly its spread in Latin America and Africa.

How does the research analyze the relationships between cholera isolates?

The research uses whole genome sequencing (WGS) single nucleotide polymorphisms (SNPs) to draw phylogenetic trees, which show the relationships between different isolates of Vibrio cholerae.

What is the stated aim of this research?

The aim of the research is to understand the relationships between cholera isolates through genetic analysis.

Sep 14, 2026

Uploaded by Jake