Fenton-Hydroxyl Radical Antioxidant Efficiency of Ibuprofen-Fe3O4-GO Nanospheres

Aug 5, 2026

Upload by Oliver

Demonstrates a one-step solvent-antisolvent oil-free acoustic emulsification approach to complex pristine ibuprofen with Fe3O4-GO as core–shell nanospheres (~50 nm). Ultrasonic complexation proceeds through hydrogen-bonding with ibuprofen side chains (CH, CH2, CH3) and C–O–H interactions between carboxylic groups and Fe–O bonds. The resulting ibuprofen-Fe3O4-GO nanospheres show strong antioxidant behavior by hydroxyl radical (·OH) scavenging and iron inactivation in electro-Fenton, achieving ~24× higher diminishing rate than free ibuprofen and ~161× over pristine ibuprofen nanoparticles in aqueous medium.

LanguageEnglish

CategoryResearch & Report

FormatPDF

Pages2

Reading Time5 min

AccessFree to download

Abstract and Approach

One-step acoustic emulsification

Complexation mechanism and structure

Antioxidant and electro-Fenton performance

FAQs

What method is used to prepare ibuprofen-Fe3O4-GO nanospheres?

A one-step solvent-antisolvent oil-free acoustic emulsification method is used to form core–shell ibuprofen-Fe3O4-GO nanospheres (~50 nm).

How does ultrasonic complexation occur between ibuprofen and Fe3O4-GO?

It occurs via hydrogen-bond formation with ibuprofen side chains and through C–O–H interactions involving carboxylic groups and Fe–O bonds.

What antioxidant performance do the synthesized nanospheres show in electro-Fenton?

They scavenge hydroxyl radicals and inactivate iron, showing about ~24× higher diminishing rate than free ibuprofen and ~161× higher than pristine ibuprofen nanoparticles in aqueous medium.

Aug 5, 2026

Upload by Oliver