Factors affecting the development of recurrence in patients who underwent tracheal resection due to tracheal stenosis - Author

Q: What was the aim of the study?

To evaluate surgical treatment outcomes for post-intubation tracheal stenosis and to identify factors associated with recurrence and treatment success.

Q: How many patients were included and how was the study conducted?

Fifty-six patients treated between January 2010 and December 2024 were retrospectively analyzed, with data collected via a standardized extraction form.

Q: Which factors were associated with higher recurrence rates?

Middle tracheal stenosis and the use of 3/0 Vicryl separating sutures were linked to higher recurrence.

Q: Did comorbidities affect recurrence risk?

Yes. Recurrence was much higher in patients with comorbidities (71.4%) than without (28.6%), with comorbidities significantly increasing recurrence likelihood (OR 9.167).

Sep 29, 2026

Upload by Olivia Brown

Background: This study evaluates surgical outcomes for post-intubation tracheal stenosis and determines factors linked to recurrence and treatment success. Methods: A retrospective analysis of 56 patients treated between January 2010 and December 2024 recorded demographics, clinical characteristics, comorbidities, surgical procedures, and postoperative outcomes using a standardized form. Results: Recurrence occurred in 14 (25%); early mortality was 1 (1.7%). Middle tracheal stenosis and 3/0 Vicryl separating sutures showed higher recurrence. Comorbidities significantly increased recurrence risk (OR 9.167). Conclusion: Post-intubation tracheal stenosis surgery remains challenging, emphasizing individualized treatment, careful technique, and comprehensive postoperative care.

LanguageEnglish

CategoryResearch & Report

FormatPDF

Pages10

Reading Time25 min

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Abstract

Background

Methods

Results

Conclusion

Keywords

Turkish Journal of Thoracic and Cardiovascular Surgery 2025;33(4):507-516 Orıgınal Artıcle / Özgün Makale Factors affecting the development of recurrence in patients who underwent tracheal resection due to tracheal stenosis Trakeal darlık nedeni ile trakea rezeksiyonu yapılan hastalarda nüks gelişimine etki eden faktörler Bahar Ağaoğlu Şanlı1􀀬, Kenan Can Ceylan1􀀬, Serkan Yazgan1􀀬, Ahmet Üçvet1􀀬, Sinan Başoğlu2􀀬, Shukur Musayev3􀀬, Özgür Samancılar3􀀬 Institution where the research was done: Dr. Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital, İzmir, Türkiye Author Affiliations: 1Department of Thoracic Surgery, University of Health Sciences, Dr. Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital, İzmir, Türkiye 2Department of Otolaryngology, İzmir Gazi Private Hospital Ear Nose and Throat Clinic İzmir, Türkiye 3Department of Thoracic Surgery, İzmir Medicana Private Hospital, İzmir, Türkiye ABSTRACT Background: This study aims to evaluate the outcomes of surgical treatment of post-intubation tracheal stenosis cases and to identify factors associated with recurrence and treatment success. Methods: Between January 2010 and December 2024, a total of 56 patients (38 males, 18 females; mean age: 49.1±14.8 years; range, 24 to 61 years) who were treated for postintubation tracheal stenosis were retrospectively analyzed. Data were collected using a standardized data extraction form . Demographic data, clinical characteristics, comorbidities, surgical procedures, and postoperative outcomes of the patients were recorded. Results: Comorbidities, particularly diabetes, were common in the majority of patients. Recurrence occurred in 14 (25%) of the cohort. Early mortality was observed in one (1.7%) patient. Middle tracheal stenosis as the site of stenosis and the use of 3/0 Vicryl separating sutures had higher recurrence rates. The mean length of the removed segment was 3.7±0.7 cm in patients without recurrence, while it was 3.2±0.5 cm in patients with recurrence (p=0.361) . While the recurrence rate was 71.4% among patients with comorbidities such as diabetes, hypertension, epilepsy, and Crohn's disease, this rate was 28.6% in those without comorbidities (p<0.001), and the presence of comorbidities significantly increased the likelihood of recurrence (odds ratio [OR]=9.167, 95% confidence interval [CI]: 3.482-24.134, p<0.001) . Conclusion: Surgical treatment of post-intubation tracheal stenosis presents challenges due to the high recurrence rate, particularly inpatients with comorbidities. Individualized treatment approaches, meticulous surgical techniques, and comprehensive postoperative care are essential to improve patient outcomes. Keywords: Post-intubation, tracheal stenosis, tracheal surgery. ÖZ Amaç: Bu çalışmada, entübasyon sonrası trakeal darlıklı olgularıncerrahi tedavi sonuçları değerlendirildi ve nüks ve tedavi başarısı ile ilişkili faktörler belirlendi. Çalışma planı: Ocak 2010 - Aralık 2024 tarihleri arasında entübasyon sonrası trakeal darlık nedeniyle tedavi edilentoplam 56 hasta (38 erkek, 18 kadın; ort. yaş: 49.1±14.8 yıl; dağılım, 24-61 yıl) retrospektif olarak incelendi. Veriler standartlaştırılmış bir veri çıkarma formu kullanılarak toplandı . Hastaların demografik özellikleri, klinik özellikleri, eşlik eden hastalıkları, cerrahi işlemler ve ameliyat sonrası sonuçları kaydedildi. Bulgular: Hastaların birçoğunda başta diyabet olmak üzereeşlik eden hastalıklar yaygındı . Kohortun 14’ünde (%25) nüksgörüldü . Bir (%1.7) hastada erken dönem mortalite gözlendi. Darlık yeri olarak orta seviyedeki trakeal darlık ve 3/0 Vicrylsepare sütür kullanımı daha yüksek nüks oranlarına sahipti. Nüks olmayan hastalarda ortalama çıkarılan segment uzunluğu 3.7±0.7 cm iken, nüks görülen hastalarda 3.2±0.5 cm idi (p=0.361) . Diyabet, hipertansiyon, epilepsi, Crohn hastalığı gibieşlik eden hastalıkları hastalar arasında nüks oranı %71.4 iken, eşlik eden

FAQs

What was the aim of the study?

To evaluate surgical treatment outcomes for post-intubation tracheal stenosis and to identify factors associated with recurrence and treatment success.

How many patients were included and how was the study conducted?

Fifty-six patients treated between January 2010 and December 2024 were retrospectively analyzed, with data collected via a standardized extraction form.

Which factors were associated with higher recurrence rates?

Middle tracheal stenosis and the use of 3/0 Vicryl separating sutures were linked to higher recurrence.

Did comorbidities affect recurrence risk?

Yes. Recurrence was much higher in patients with comorbidities (71.4%) than without (28.6%), with comorbidities significantly increasing recurrence likelihood (OR 9.167).

Sep 29, 2026

Upload by Olivia Brown