Estimating the Disability-Adjusted Life-Years (DALYs) of Five Most Prevalent Cancers in the Elderly in Markazi Province, Iran, 2019

Sep 21, 2026

Cancer affects elderly populations and can cause substantial loss of life years. This secondary study assessed incidence and burden of five prevalent cancers—skin, breast, gastric, colorectal, and lung—in individuals older than 60 in Markazi province in 2019. Data were drawn from the population-based cancer registry and death registration sources, with analysis using Excel and DISMOD2. DALYs were computed using DALY = YLL + YLD to quantify mortality and disability, revealing higher incidence, mortality, and DALY values in the elderly.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages7

Reading Time18 min

AccessFree to download

Abstract

Background

Methods

Data sources

Analysis approach

Results

Conclusion

Keywords

Original Article [http://mjiri.iums.ac.ir](http://mjiri.iums.ac.ir) Medical Journal of the Islamic Republic of Iran (MJIRI) MedJ Islam Repub Iran. 2024 (12 Aug);38.92. [https://doi.org/10.47176/mjiri.38.92](https://doi.org/10.47176/mjiri.38.92) Estimating the Disability-Adjusted Life-Years (DALYs) of Five Most Prevalent Cancers in the Elderly in Markazi Province, Iran, 2019 Ahmad Amani1, Reza Fadayevatan1, Babak Eshrati2, Mohammad Rafiee3, Ahmad Ali Akbari Kamrani1 * Received: 24 Apr 2023 Published: 12 Aug 2024 Abstract Background: Cancer is one of the diseases affecting the elderly and can lead to loss of life years. The skin, breast, gastric, colorectal, and lung cancers are five prevalent cancers in the elderly. The present study was conducted to evaluate the incidence and burden of these cancers in the elderly. Methods: This secondary study was conducted on available extracted data from the population-based cancer registry in Markazi province in 2019. The data of all cases older than 60 years that lived more than six months in Markazi province were extracted. Collecting information involves gathering data on cancer incidence and death rates based on age and sex groups, as well as overall mortality rates. This also includes survival rates, recovery rates for cancer patients, and disability attributed to cancer using the global burden of disease (GBD) standard table from various sources. Various data, including the latest death registration report and the latest cancer registration report for 2019 and the Iran Statistics Center, were obtained. In order to check and analyze the data, Excel and DISMOD2 software were used. In order to analyze the data, formulas for calculating the burden of diseases (DALY=YLL+YLD) were used. For the validity and reliability of the data, the method of preventing the registration of impossible codes and useless codes was used. Results: The incidence rate of skin, breast, gastric, colorectal, and lung cancers in elderly women was 52.87, 59.02, 67.63, 47.95, and 20.90, respectively, per 100000. DALYs of these cancers in elderly women were 63.15, 423.86, 686.37, 366.49, and 385.18, respectively. The incidence rate of skin, gastric, colorectal, and lung cancers in elderly men was 100.84, 135.80, 49.74, and 68.57, respectively per 100000. DALYs of these cancers in elderly men were 342.31, 1117.01, 337.99, and 452.41, respectively. The highest YLL and YLD were related to gastric cancer (493.31/100,000) and breast cancer (220.84/100,000) Conclusion: Based on the results of this study, the incidence, mortality, and DALY of skin, breast, stomach, colorectal and lung cancers were higher in the elderly. In this study, the burden of some cancers such as breast, was lower compared to provinces such as Yazd. Keywords: Cancer, Incidence Rate, Disability Adjusted Life Years, Elder Conflicts of Interest: None declared Funding: None *This work has been published under CC BY-NC-SA 1.0 license. Copyright© Iran University of Medical Sciences Cite this article as: Amani A, Fadayevatan R, Eshrati B, Rafiee M, Akbari Kamrani AA. Estimating the Disability-Adjusted Life-Years (DALYs) of Five Most Prevalent Cancers in the Elderly in Markazi Province, Iran, 2019. Med J Islam Repub Iran. 2024 (12 Aug);38:92 . [https://doi.org/10.47176/mjiri.38.92](https://doi.org/10.47176/mjiri.38.92) Introduction Most regions of the world are getting older rapidly (1) . The statistical data show that Iran's elderly population is increasing, as well (2) . Aging is a biological process with a progressive decrease in the performance of most of the body's systems, which ultimately leads to the inability to meet the body's needs for the rest of life. The decrease in | Corresponding author: Dr Ahmad Ali Akbari Kamrani, [akbarikamrani@uswr.ac.ir](akbarikamrani@uswr.ac.ir)
[1](1). Department of Geriatrics, School of Social Welfare, University of Welfare and Rehabilitation Sciences, Tehran, Iran
2. Pr

FAQs

What is the purpose of this study regarding elderly cancer burden?

To evaluate the incidence and burden of five prevalent cancers (skin, breast, gastric, colorectal, and lung) among people aged over 60 in Markazi province in 2019.

Which data and tools were used to estimate DALYs?

The study used extracted data from the population-based cancer registry and death registration reports for 2019, analyzed with Excel and DISMOD2. DALYs were calculated using DALY = YLL + YLD.

What were the main findings on DALYs and incidence in elderly women and men?

Elderly women showed DALYs for the five cancers ranging from 63.15 to 686.37, with incidence rates per 100,000 also varying by cancer type. Elderly men similarly showed higher incidence and DALY values, with the highest YLL and YLD reported for gastric and breast cancers.

Sep 21, 2026

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