Epidemiology of cervical cancer in Iran in 2016 - A nationwide study of incidence and regional variation

Sep 21, 2026

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The study evaluates the age-standardized incidence rate (ASR) and geographic distribution of cervical cancer across Iranian provinces in 2016 using data from the National Cancer Registry. A descriptive cross-sectional design was applied, calculating crude rates and ASR per province and assessing spatial clustering with Moran's I and ArcMap GIS. Results include 808 cases (median age 52.19 years), an overall ASR of 1.90 per 100,000, and provincial ASR variations without significant clustering. Incidence was lower than the global average, with no province-level disparities identified.

LanguageEnglish

CategoryResearch & Report

FormatPDF

Pages10

Reading Time25 min

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Abstract

Background and Aims

Methods

Results

Conclusion

Introduction

DOI: 10.1002/cnr2.1973 O R IG INA L ARTI CLE Epidemiology of cervical cancer in Iran in 2016: A nationwide study of incidence and regional variation Alireza Anjam Majoumerd 1 | Saeed Hosseini 2,3 | Seyyed Mohammad Hossein Hosseini 4 | Gholamreza Roshandel 5 | Vahid Rahmanian 6 | Narjes Hazar 7 1School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 2Center for Healthcare Data Modeling, Department of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 3Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran 4Department of Biostatistics and Epidemiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 5Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran 6Department of Public Health, Torbat Jam Faculty of Medical Sciences, Torbat Jam, Iran 7Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Correspondence Narjes Hazar, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Email: [narjeshazar@yahoo.com](narjeshazar@yahoo.com) Abstract Background: Cervical cancer is a common, and fatal cancer in women worldwide. This cancer is the fourth most common cancer in women after breast, colorectal, and lung cancer. Aims: This study aims to investigate the age-standardized incidence rate (ASR) and the geographical distribution of Cervical Cancer in Iran. Methods: This study was designed as a descriptive cross-sectional investigation. The study sample comprised all individuals registered as cervical cancer patients in the National Cancer Registry system in 2016 . The crude rate and ASR for each province were computed independently. Furthermore, we employed ArcMap10 . 5 software and geographic information system to conduct an analysis of the gathered data. In order to ascertain the spatial distribution and clustering of cervical cancer incidence, we utilized Moran's I, which measures spatial autocorrelation. Results: We studied a total of 808 cases of cervical cancer with a median age to be 52. 19 years (IQR≈1 .35) . Among these cases, 685 (84 . 7%) were diagnosed based on the pathological reports with morphological verification, while 81 patients (10.1%) were clinically identified, and 42 cases (5.2%) were diagnosed using the death certificate-only method. Squamous cell carcinoma accounted for 61% of all cases (n = 497) . The ASR of cervical cancer in Iran was 1 .90 per 100 000 populations. The provincial ASR ranged from 0.29 to 5.03 per 100 000, with the highest rates observed in Golestan (5 .03), East Azerbaijan (4 .07), and Ilam (3 . 72) . We found no clustering patterns in the distribution of provincial crude, age-specific, and agestandardized incidence rates (p > .05) . Conclusion: The incidence of cervical cancer in Iran was lower than the global average, and we did not identify any significant disparities in the incidence rates among the provinces. Although there were differences in incidence rates among the areas, these were not clustered. It is crucial to remember that cervical cancer is still a major public health issue in Iran, and in order to lessen the disease's burden, national This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2024 The Authors. Cancer Reports published by Wiley Periodicals LLC. Cancer Reports. 2024;7:e1973 . [https://doi.org/10.1002/cnr2.1973](https://doi.org/10.1002/cnr2.1973) [wileyonlinelibrary.com/journal/cnr2](wileyonlinelibrary.com/journal/cnr2) 1 of 10 initiatives to enhance screening, early identification, and access to efficient treatment should continue to be top priorities. KEYWOR DS cervical cancer, epidemiology, incidence, Iran 1

FAQs

What is the main goal of the nationwide study on cervical cancer in Iran for 2016?

To investigate the age-standardized incidence rate and the geographical distribution of cervical cancer across Iran.

How were incidence rates analyzed across provinces?

Crude rates and ASR were computed for each province, and spatial clustering was assessed using Moran's I with ArcMap/GIS.

What were the key results regarding the overall and provincial incidence rates?

The study reported 808 cases and an overall ASR of 1.90 per 100,000, with provincial ASR ranging from 0.29 to 5.03; the highest rates were observed in Golestan, East Azerbaijan, and Ilam.

Did the study find clustering or significant disparities between provinces?

No clustering patterns were identified for provincial crude, age-specific, or age-standardized rates (p > .05), and no significant disparities were detected among provinces.

Sep 21, 2026

Uploaded by Himbo