Enhanced recovery after surgery protocol implementation in pediatric Meckel’s diverticulum resection - clinical outcome study

Q: How were patients grouped in the retrospective cohort study?

Patients (n=78) were divided into a Traditional care group (n=38, Jan 2017–Dec 2020) and an ERAS protocol group (n=40, Jan 2021–Mar 2025).

Q: What were the key outcomes of implementing ERAS?

ERAS significantly shortened postoperative length of stay and improved pain management and recovery measures, including faster gastrointestinal recovery and earlier total enteral nutrition, with maintained safety.

Sep 28, 2026

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Enhanced recovery after surgery (ERAS) pathways are established for many adult operations, yet pediatric-specific ERAS guidance remains insufficient. This retrospective cohort study assessed clinical outcomes of ERAS protocols in pediatric laparoscopic Meckel’s diverticulum resection. Seventy-eight consecutive cases (Jan 2017–Mar 2025) were compared between traditional care and an ERAS protocol. ERAS reduced postoperative length of stay, improved pain and gastrointestinal recovery, and optimized inflammatory and fluid-related markers while maintaining safety.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages13

Reading Time33 min

AccessFree to download

Abstract

Background and Aim

Methods

Results

Conclusion

| W | J | G | S | World Journal of
Gastrointestinal Surgery | | --- | --- | --- | --- | --- | Submit a Manuscript: [https://www.f6publishing.com](https://www.f6publishing.com) World J Gastrointest Surg 2025 December 27; 17(12): 113407 DOI: 10.4240/wjgs.v17.i12.113407 ISSN 1948-9366 (online) ORIGINAL ARTICLE Retrospective Cohort Study Enhanced recovery after surgery protocol implementation in pediatric Meckel’s diverticulum resection: A clinical outcome study Kai Zhu, Xiao Zhang, Yan Li, Yan Gao, Yong-Mei Tong, Jing-Jing He, Yi-Lin Su Specialty type: Surgery Provenance and peer review: Unsolicited article; Externally peer reviewed. Peer-review model: Single blind Peer-review report’s classification Scientific Quality: Grade C Novelty: Grade B Creativity or Innovation: Grade C Scientific Significance: Grade C P-Reviewer: Molasy B, PhD, Assistant Professor, Poland Received: August 25, 2025 Revised: September 22, 2025 Accepted: November 6, 2025 Published online: December 27, 2025 Processing time: 122 Days and 16.2 Hours Kai Zhu, Xiao Zhang, Yan Li, Yan Gao, Yong-Mei Tong, Yi-Lin Su, Department of Pediatric Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, Anhui Province, China Jing-Jing He, Department of Reproductive Medicine Center, Hefei Maternal and Child Health Hospital, Hefei 230001, Anhui Province, China Co-first authors: Kai Zhu and Xiao Zhang. Co-corresponding authors: Jing-Jing He and Yi-Lin Su. Corresponding author: Yi-Lin Su, MD, Director, Professor, Department of Pediatric Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, No. 17 Lujiang Road, Luyang District, Hefei 230001, Anhui Province, [China.](China. zk030405@163.com)[ zk030405@163.com](China. zk030405@163.com) Abstract BACKGROUND Enhanced recovery after surgery (ERAS) guidelines have been established for multiple types of adult surgeries. However, ERAS guidelines tailored to pediatric surgeries remain to be developed. AIM To evaluate the clinical outcomes of ERAS protocols in pediatric laparoscopic Meckel’s diverticulum resection. METHODS This retrospective cohort study analyzed 78 consecutive pediatric cases treated between January 2017 and March 2025. Patients were divided into: Traditional care group (n = 38): January 2017-December 2020; ERAS protocol group (n = 40): January 2021-March 2025. We compared perioperative outcomes, including clinical recovery parameters and laboratory markers, to assess protocol efficacy. RESULTS All procedures were completed laparoscopically by the same surgical team without conversion. Baseline characteristics, including demographics, diverticulum location, and intraoperative parameters (operative time, blood loss), were comparable between groups (all P > 0.05) . The ERAS protocol demonstrated WJGS [https://www.wjgnet.com](https://www.wjgnet.com) 1 December 27, 2025 Volume 17 Issue 12 Zhu K et al. ERAS for pediatric MD surgery significantly shorter postoperative length of stay (7.55 ± 1.52 days vs 10.40 ± 3.59 days, P < 0.001) while complication rates were numerically lower in the ERAS group (17.50% vs 13.16%, P = 0.595) . Additional benefits of ERAS implementation included: Reduced intravenous fluid requirements (5.00 mL/kg/hour vs 8.00 mL/kg/hour), accelerated gastrointestinal recovery (first flatus: 2.00 days vs 3.00 days), lower pain scores (P < 0.001), earlier total enteral nutrition achievement (5.00 days vs 6.50 days) and shorter intravenous therapy duration (6.00 days vs 8.00 days; all P < 0.001). ERAS patients also showed reduced drainage utilization (P < 0.05) and improved inflammatory marker profiles postoperatively [neutrophils: (5.98 ± 2.02) × 109/L vs (8.01 ± 3.98) × 109/L]; median Creactive protein: 13.6 mg/L 7 vs 19.63 mg/L) . Glycemic control was super

FAQs

What is the study’s main objective?

To evaluate the clinical outcomes of ERAS protocols in pediatric laparoscopic Meckel’s diverticulum resection.

How were patients grouped in the retrospective cohort study?

Patients (n=78) were divided into a Traditional care group (n=38, Jan 2017–Dec 2020) and an ERAS protocol group (n=40, Jan 2021–Mar 2025).

What were the key outcomes of implementing ERAS?

ERAS significantly shortened postoperative length of stay and improved pain management and recovery measures, including faster gastrointestinal recovery and earlier total enteral nutrition, with maintained safety.

Sep 28, 2026

Uploaded by Grenda