Dietary fiber as a microbiota-modulating strategy after endoscopic mucosa resection: A new frontier in postoperative care

Sep 28, 2026

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Emerging evidence emphasizes the critical role of the intestinal microbiota in postoperative recovery and long-term outcomes after gastrointestinal procedures. This editorial comments on a retrospective study by Niu et al, which shows that dietary fiber supplementation supports gut microbiota restoration following endoscopic mucosa resection. The results suggest fiber can modulate gut communities and aid recovery, while highlighting the need for prospective randomized trials to define optimal fiber type, dose, and duration. The discussion frames fiber as microbiota-targeted nutrition for personalized postoperative care.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages8

Reading Time20 min

AccessFree to download

Editorial

Abstract

Key Words

Core Tip

Introduction

Mucosal barrier and microbiota changes after EMR

| W | J | G | S | World Journal of
Gastrointestinal Surgery | | --- | --- | --- | --- | --- | Submit a Manuscript: [https://www.f6publishing.com](https://www.f6publishing.com) World J Gastrointest Surg 2025 December 27; 17(12): 110619 DOI: 10.4240/wjgs.v17.i12.110619 ISSN 1948-9366 (online) EDITORIAL Dietary fiber as a microbiota-modulating strategy after endoscopic mucosa resection: A new frontier in postoperative care Duygu Kirkik, Betul Dogantekin, Sevgi Kalkanli Tas, Burak Sarikaya Specialty type: Gastroenterology and hepatology Provenance and peer review: Invited article; Externally peer reviewed. Peer-review model: Single blind Peer-review report’s classification Scientific Quality: Grade B, Grade B, Grade B, Grade B, Grade C Novelty: Grade B, Grade B, Grade C, Grade C, Grade C Creativity or Innovation: Grade B, Grade B, Grade C, Grade C, Grade C Scientific Significance: Grade B, Grade C, Grade C, Grade C, Grade C P-Reviewer: Li B, PhD, Professor, China; Ren L, PhD, China; Zhou HX, PhD, Assistant Professor, Post Doctoral Researcher, China Received: June 13, 2025 Revised: July 30, 2025 Accepted: September 11, 2025 Published online: December 27, 2025 Processing time: 196 Days and 0 Hours Duygu Kirkik, Sevgi Kalkanli Tas, Department of Immunology, Hamidiye Medicine Faculty, University of Health Sciences, Istanbul 34668, Türkiye Duygu Kirkik, Department of Medical Biology, Hamidiye Medicine Faculty, University of Health Sciences, Istanbul 34668, Türkiye Betul Dogantekin, Internal Medicine, University of Health Sciences, Sultan 2 Abdulhamid Han Training and Research Hospital, Istanbul 34668, Türkiye Burak Sarikaya, Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Sultan 2 Abdulhamid Han Training and Research Hospital, Istanbul 34668, Turkiye Corresponding author: Duygu Kirkik, Assistant Professor, Department of Immunology, Hamidiye Medicine Faculty, University of Health Sciences, No. 38 Tıbbiye Cad, Mekteb-i Tıbbiye-i Şâhane (Haydarpaşa), Külliyesi Selimiye Mah, Istanbul 34668, Türkiye. [dygkirkik@gmail.com](dygkirkik@gmail.com) Abstract Emerging evidence underscores the critical role of intestinal microbiota in postoperative recovery and long-term outcomes of gastrointestinal procedures. In this editorial, we comment on the retrospective study by Niu et al, which highlights the beneficial impact of dietary fiber supplementation on gut microbiota restoration following endoscopic mucosa resection. The findings highlight the potential of fiber supplementation to modulate gut microbiota and support recovery following endoscopic mucosa resection. Nonetheless, we also emphasize the need for prospective, randomized studies to delineate the optimal type, dose, and duration of fiber supplementation. This research represents a significant step toward evidence-based nutritional interventions in minimally invasive gastrointestinal surgery and underscores the importance of microbiota-targeted therapies in personalized postoperative care. Key Words: Gut microbiota; Dietary fiber; Endoscopic mucosal resection; Short-chain fatty acids; Mucosal healing; Precision nutrition ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. WJGS [https://www.wjgnet.com](https://www.wjgnet.com) 1 December 27, 2025 Volume 17 Issue 12 Kirkik D et al. Dietary fiber and microbiota modulation after EMR Core Tip: This study highlights the novel role of dietary fiber as a microbiota-targeted therapy in patients undergoing endoscopic mucosal resection. By restoring microbial diversity and enhancing barrier integrity, fiber supplementation offers a non-invasive, immunologically informed approach to optimize postoperative recovery. The discussion findings underscore the need for precision nutrition strategies tailored to individual microbial and immune profiles to reduce complications and improve long-term gastrointestinal

FAQs

What is the main clinical focus of the editorial?

The editorial focuses on how dietary fiber supplementation may modulate gut microbiota and support postoperative recovery after endoscopic mucosa resection.

What evidence is discussed regarding dietary fiber after EMR?

It comments on Niu et al’s retrospective study, reporting beneficial effects on gut microbiota restoration following EMR and emphasizing recovery support.

Why are prospective randomized studies needed?

Because the editorial underscores the need to determine the optimal fiber type, dose, and duration with higher-quality prospective evidence.

Sep 28, 2026

Uploaded by Aldword