Correction - Correction: Systemic Expression of Kaposi Sarcoma Herpesvirus (KSHV) Vflip in Endothelial Cells Leads to a Profound Proinflammatory Phenotype and Myeloid Lineage Remodeling In Vivo

Sep 29, 2026

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This correction addresses errors in a previously published PLOS Pathogens article describing systemic expression of Kaposi Sarcoma Herpesvirus (KSHV) Vflip in endothelial cells. The update clarifies that the Fig 2B TG/B-Cells EGFP panel was incorrect and provides a corrected EGFP panel with corresponding revised H&E, CD31, and Ki67 panels from the same specimen. It also removes an incorrect PROX-1 reference from the Fig 2 legend and supplies additional EGFP and Ki67 stained panels from a second specimen as supporting information.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages2

Reading Time5 min

AccessFree to download

Correction

Updated figures and legend

Supporting information (S1 File)

OPEN ACCESS Citation: Ballon G, Akar G, Cesarman E (2026) Correction: Systemic Expression of Kaposi Sarcoma Herpesvirus (KSHV) Vflip in Endothelial Cells Leads to a Profound Proinflammatory Phenotype and Myeloid Lineage Remodeling In Vivo. PLoS Pathog 22(1): e1013809. [https://doi.org/10.1371/](https://doi.org/10.1371/)[ ](https://doi.org/10.1371/)[journal.ppat.1013809](journal.ppat.1013809) Published: January 5, 2026 Copyright: © 2026 Ballon et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. CORRECTION Correction: Systemic Expression of Kaposi Sarcoma Herpesvirus (KSHV) Vflip in Endothelial Cells Leads to a Profound Proinflammatory Phenotype and Myeloid Lineage Remodeling In Vivo Gianna Ballon, Gunkut Akar, Ethel Cesarman The Fig 2B TG/B-Cells EGFP panel is incorrect. The updated Fig 2 below presentsa corrected EGFP TG/B-Cell panel, along with updated H&E, CD31 and Ki67 panels originating from the same specimen. Furthermore, the original Fig 2 legend included an incorrect reference to PROX-1-stained sections which has been removed from the updated Fig 2 legend below. Similarities were noted between the Fig 2B TG/Endo EGFP and Ki67 panels and the Fig S3 TG/Endo panel. The corresponding author EC stated that these slides were taken from serial sections of the same muscle specimen and the same areas were selected deliberately for the images shown. Additional panels presenting EGFP and Ki67 stained TG/Endo sections from a second specimen are provided in S1 File. Supporting information S1 File. Additional images of EGFP and Ki67 stained skeletal muscle cells from TG/Endo mice, derived from a second specimen and supplementary to their respective panels in Fig 2B. (TIF) Reference 1. Ballon G, Akar G, Cesarman E. Systemic expression of Kaposi sarcoma herpesvirus (KSHV) Vflip in endothelial cells leads to a profound proinflammatory phenotype and myeloid lineage remodeling in vivo. PLoS Pathog. 2015;11(1):e1004581 . [https://doi.org/10.1371/journal.ppat.1004581](https://doi.org/10.1371/journal.ppat.1004581) PMID: 25607954 PLOS Pathogens | [https://doi.org/10.1371/journal.ppat.1013809](https://doi.org/10.1371/journal.ppat.1013809) January 5, 2026 1 / 2 Fig 2. Systemic endothelial abnormalities. (A) A representative cardiac section stained with H&E, EGFP and CD34 and/or CD31, and Ki67 shows numerous atypical spindle-like endothelial cells. Similar cells were found in the skeletal muscle (B) and in brown fat (C) . Analysis was done in 2–3 month-old mice, about one month after i.p. injection of tamoxifen. Scale bar, 200 μm. TG/Endo, ROSA26 .vFLIP;Cdh5(PAC) .creERT2; TG/B-cells, ROSA26 .vFLIP;CD19 .cre mice used as control. [https://doi.org/10.1371/journal.ppat.1013809.g002](https://doi.org/10.1371/journal.ppat.1013809.g002) PLOS Pathogens | [https://doi.org/10.1371/journal.ppat.1013809](https://doi.org/10.1371/journal.ppat.1013809) January 5, 2026 2 / 2

FAQs

What specific figure panel was corrected in this notice?

The notice states that the Fig 2B TG/B-Cells EGFP panel was incorrect and provides an updated corrected EGFP panel.

What other figure panels were updated along with the EGFP correction?

Updated H&E, CD31, and Ki67 panels are provided, originating from the same specimen as the corrected EGFP panel.

What additional material was provided for further clarification?

The authors provide additional EGFP and Ki67 stained images from a second TG/Endo specimen as Supporting Information in S1 File, and they removed the incorrect PROX-1 reference from the Fig 2 legend.

Sep 29, 2026

Uploaded by Elsa