Comparison of short-term outcomes of robotic-assisted radical colon cancer surgery using the Kangduo Surgical Robotic System and the da Vinci Si Robotic System - a prospective cohort study

Sep 21, 2026

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A prospective cohort comparison evaluates surgical quality and short-term oncologic outcomes for colon cancer patients treated with the Kangduo Surgical Robotic System versus the da Vinci Si robotic system. The study draws on a multicenter randomized controlled noninferiority trial subcohort from three Chinese centers, assigning patients to KD-SR-01 or da Vinci Si with masked pathological outcome assessment. Among 58 patients, both systems achieved 100% surgical success with comparable equipment workload, intraoperative sensation, adverse events, complication rates, operative times, bleeding, and postoperative pathological outcomes. Results support noninferiority in experienced surgeons’ use.

LanguageEnglish

CategoryResearch & Report

FormatPDF

Pages8

Reading Time20 min

AccessFree to download

Background

Methods

Endpoints and masking

Results

Conclusions

Keywords

’Prospective Cohort Study Comparison of short-term outcomes of roboticassisted radical colon cancer surgery using the Kangduo Surgical Robotic System and the Da Vinci Si Robotic System: a prospective cohort study Yunxiao Liu, MDa , Yuliuming Wang, MDa , Chunlin Wang, MDa , Xin Wang, MSca , Xin Zhang, MSca , Yihaoran Yang, MSca , Zhengqiang Wei, MDb,* , Yi Xiao, MDc,* , Guiyu Wang, MDa,* Background: Robotic surgery has been a revolution for colon cancer (CC) patients, with the increasing availability of different competitive robotic systems, but evidence of relevant oncologic outcomes is indeed scarce. Our goal was to compare the surgical quality and short-term oncologic outcomes of the Kangduo Surgical Robotic System and the da Vinci Si Robotic System in patients with CC. Methods: These are results from a subcohort of a multicenter randomized controlled noninferiority trial performed in three centers in China. Enrolled patients were randomly assigned to undergo surgery using either the KD-SR-01 system (KD group) or the da Vinci Si (DV) robotic system (DV group) . Neither investigators nor patients were masked to treatment allocation, but assessment of pathological outcomes was masked to treatment allocation. The primary endpoint was surgical success rate. The secondary endpoints were surgical outcomes, pathologic outcomes, and postoperative outcomes. The study is [registered at www.chictr.org.cn](registered at www.chictr.org.cn) (ChiCTR22000 63172) . Although the long-term follow-up results were not a predeﬁned endpoint for this study, late-stage work is in progress. Results: A total of 58 CC patients were included in this study, 28 in the KD group and 30 in the DV group. All patients were successfully operated without any intermediate open/conventional laparoscopic surgery and the success rate of surgery was 100% . Assessment of equipment docking task load and intraoperative operating sensation score were similar between the two groups. Adverse events and Clavien–Dindo grade II or higher grade complication rates were comparable between the two groups. Device arm docking time, robotic arm operation time, and intraoperative bleeding were not signiﬁcantly different between the two groups. Similar results were obtained from postoperative pathological outcomes and internal environment indexes. Conclusions: The efﬁcacy and safety of the Kangduo Robotic Surgical System has been proved, operation of the Kangduo Robotic System by experienced surgeons for CC is not less effective than the da Vinci robotic System. Keywords: colon cancer, da Vinci Robotic System, Kangduo Robotic system, short-term outcomes Introduction Colon cancer (CC) is currently one of the most common malignant tumors of the gastrointestinal system worldwide, with high morbidity and mortality rates[1] . CC radical surgery is currently the standard strategy for the treatment of nonmetastatic CC, and laparoscopic surgery is also recognized as the treatment of choice, which has the advantages of less surgical trauma, less bleeding, and shorter recovery time[2,3] . Although laparoscopic surgery is amore advantageous surgical platform, there are several drawbacks aDepartment of Colorectal Cancer Surgery, The Second Afﬁliated Hospital of Harbin Medical University, Harbin, bDepartment of Gastrointestinal Surgery, The First Afﬁliated Hospital of Chongqing Medical University, Chongqing and cDepartment of General Surgery, Division of Colorectal Surgery, Peking Union Medical College, Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. *Corresponding authors. Address: Department of Colorectal Cancer Surgery, The Second Afﬁliated Hospital of Harbin Medical University, No. 246 Xuefu Road, Harbin, Heilongjiang 150086, People’s Republic of China. Tel.: +861 [394 513 3256. E-mail: guiywang

FAQs

What was the primary goal of the study?

To compare surgical quality and short-term oncologic outcomes between the Kangduo Surgical Robotic System and the da Vinci Si system in colon cancer patients.

How were patients assigned to the two robotic systems?

Patients from a multicenter randomized controlled noninferiority trial subcohort were randomly assigned to KD-SR-01 (KD group) or da Vinci Si (DV group). Investigators and patients were not masked, but pathological outcome assessment was masked.

What were the key findings regarding safety and outcomes?

Surgical success was 100% in both groups, and adverse events and complication rates (Clavien–Dindo grade II or higher) were comparable. Operative metrics and postoperative pathological outcomes showed similar results as well.

Sep 21, 2026

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