Colorectal cancer’s burden attributable to a diet high in processed meat in the Belt and Road Initiative countries

Q: What is the study focusing on regarding colorectal cancer in B and R countries?

It evaluates the burden and trends of colorectal cancer attributable to a diet high in processed meat (DHPM-CRC) across Belt and Road Initiative countries from 1990 to 2019.

Q: How did the researchers quantify DHPM-CRC burden and trends?

They used the 2019 Global Burden of Disease Study, calculating deaths and age-standardized rates, including DALYs, then applied joinpoint regression with AAPC to analyze temporal trends.

Q: What were the main findings about variation and direction of DHPM-CRC burden?

The burden varied by geography; it generally increased across most member countries from 1990 to 2019 (all P < 0.05). The highest-ranking countries differed between 1990 and 2019, and trends varied by region, sex, and age group.

Sep 21, 2026

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Colorectal cancer (CRC) drives substantial morbidity, mortality, and economic costs across the Belt and Road Initiative (“B and R”) countries, where processed meat consumption is also high. Yet the CRC burden and its temporal trends linked to a diet high in processed meat (DHPM-CRC) from 1990 to 2019 have been unclear. Using the 2019 Global Burden of Disease Study, deaths and DALYs were assessed with age-standardized rates and joinpoint regression (AAPC) to evaluate 1990–2019 and 2010–2019 changes.

LanguageEnglish

CategoryResearch & Report

FormatPDF

Pages16

Reading Time40 min

AccessFree to download

Abstract

Background

Aim

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Results

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Key Words

| W | J | G | O | World Journal of
Gastrointestinal Oncology | | --- | --- | --- | --- | --- | Submit a Manuscript: [https://www.f6publishing.com](https://www.f6publishing.com) World J Gastrointest Oncol 2024 January 15; 16(1): 182-196 DOI: 10.4251/wjgo.v16.i1.182 ISSN 1948-5204 (online) ORIGINAL ARTICLE Basic Study Colorectal cancer’s burden attributable to a diet high in processed meat in the Belt and Road Initiative countries Gu Liu, Chang-Min Li, Fei Xie, Qi-Lai Li, Liang-Yan Liao, Wen-Jun Jiang, Xiao-Pan Li, Guan-Ming Lu Specialty type: Oncology Provenance and peer review: Invited article; Externally peerreviewed. Peer-review model: Single-blind Peer-review report’s scientific quality classification Grade A (Excellent): A Grade B (Very good): 0 Grade C (Good): C, C Grade D (Fair): 0 Grade E (Poor): 0 P-Reviewer: Ahmed M, United States; Batyrbekov K, Kazakhstan; Mohamed SY, Egypt Received: October 1, 2023 Peer-review started: October 1, 2023 First decision: October 18, 2023 Revised: October 20, 2023 Accepted: December 11, 2023 Article in press: December 11, 2023 Published online: January 15, 2024 Gu Liu, Chang-Min Li, Guan-Ming Lu, Department of Gastrointestinal Surgery, The First Affiliated Hospital, Jinan University, Guangzhou 510630, Guangdong Province, China Gu Liu, Fei Xie, Qi-Lai Li, Department of Gastrointestinal Surgery, Chenzhou Third People’s Hospital, Chenzhou 423000, Hunan Province, China Chang-Min Li, Department of Gastrointestinal Surgery, Chenzhou First People’s Hospital and the First Affiliated Hospital of Xiangnan University, Chenzhou, 423000 Hunan Province, China Liang-Yan Liao, Wen-Jun Jiang, Guan-Ming Lu, Department of Breast and Thyroid Surgery, the Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, Guangxi Zhuang Autonomous Region, China Xiao-Pan Li, Department of Health Management Center, Zhongshan Hospital, Shanghai Medical College ofFudan University, Shanghai 200032, China Corresponding author: Xiao-Pan Li, PhD, Adjunct Associate Professor, Department of Health Management Center, Zhongshan Hospital, Shanghai Medical College ofFudan University, No. 180 Fenlin Road, Shanghai 200032, [China.](China. xiaopanli0224@126.com)[ xiaopanli0224@126.com](China. xiaopanli0224@126.com) Abstract BACKGROUND Colorectal cancer (CRC) plays a significant role in morbidity, mortality, and economic cost in the Belt and Road Initiative (“B and R”) countries. In addition, these countries have a substantial consumption of processed meat. However, the burden and trend of CRC in relation to the consumption of a diet high in processed meat (DHPM-CRC) in these “B and R” countries remain unknown. AIM To analyze the burden and trend of DHPM-CRC in the “B and R” countries from 1990 to 2019. METHODS We used the 2019 Global Burden of Disease Study to collate information regarding the burden of DHPM-CRC. Numbers and age-standardized rates (ASRs) of deaths along with the disability-adjusted life years (DALYs) were determined among the “B and R” countries in 1990 and 2019. Using joinpoint regression analysis, the average annual percent change (AAPC) was used to WJGO [https://www.wjgnet.com](https://www.wjgnet.com) 182 January 15, 2024 Volume 16 Issue 1 Liu G et al. CRC burden of “B and R” countries analyze the temporal trends of age-standardized DALYs rate (ASDALR) from 1990 to 2019 and in the final decade (2010–2019) . RESULTS We found geographical differences in the burden of DHPM-CRC among “B and R” countries, with the three highest-ranking countries being the Russian Federation, China, and Ukraine in 1990, and China, the Russian Federation, and Poland in 2019. The burden of DHPM-CRC generally increased in most member countries from 1990 to 2019 (all P < 0.05) . The absolute number of deaths and DALYs in DHPM-CRC were 3151.15 [95% uncertainty interval (UI) 665.74-5696.64] and 83249.31 (95%UI 15628.64-151956.

FAQs

What is the study focusing on regarding colorectal cancer in B and R countries?

It evaluates the burden and trends of colorectal cancer attributable to a diet high in processed meat (DHPM-CRC) across Belt and Road Initiative countries from 1990 to 2019.

How did the researchers quantify DHPM-CRC burden and trends?

They used the 2019 Global Burden of Disease Study, calculating deaths and age-standardized rates, including DALYs, then applied joinpoint regression with AAPC to analyze temporal trends.

What were the main findings about variation and direction of DHPM-CRC burden?

The burden varied by geography; it generally increased across most member countries from 1990 to 2019 (all P < 0.05). The highest-ranking countries differed between 1990 and 2019, and trends varied by region, sex, and age group.

Sep 21, 2026

Uploaded by Himbo