Clinical and Imaging Correlates of Radial Styloid Changes in De Quervain’s Tenosynovitis - A Cross-Sectional Observational Study

Sep 30, 2026

De Quervain’s Tenosynovitis is a common wrist musculoskeletal condition associated with pain and impaired function. The study evaluates whether radial styloid osseous changes relate to pain severity, symptom duration, and clinical outcomes. Thirty-two participants were assessed clinically (pain, tenderness, swelling, and range-of-motion restriction) and by imaging for radial styloid abnormalities and tendon sheath inflammation, with predictors analyzed via descriptive statistics and multiple regression.

LanguageEnglish

CategoryHealthcare

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Reading Time8 min

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Abstract

Introduction

Materials and Methods

Study population and selection criteria

Clinical assessment and data collection

Results

Conclusion

Original Research Clinical and Imaging Correlates of Radial Styloid Changes in De Quervain’s Tenosynovitis: A Cross‑Sectional Observational Study Suriya P. Raja1, Rajavel Kalirajan1, Saravanan Vasudevan1, Praveen R. Mathiazhagan1, Madhan Raju1, Bandari Kaavya2, Panneerselvam Periasamy3 1Department of Orthopaedics, SRM Medical College Hospital and Research Centre, Chennai, Tamil Nadu, India, 2Department of Radiodiagnosis, SRM Medical College Hospital and Research Centre, Chennai, Tamil Nadu, India, 3Department of Physiology, Government Erode Medical College, Erode, Tamil Nadu, India Submitted: 29‑Jul‑2025 Revised: 01‑Aug‑2025 Accepted: 06‑Aug‑2025 Published: 22‑Dec‑2025 Abstract Introduction: De Quervain’s Tenosynovitis is a common musculoskeletal condition affecting the wrist, often associated with pain and functional limitations. While clinical features are well documented, the role of osseous changes in the radial styloid and their impact on symptom severity remain unclear. Aim: The aim of the paper is to evaluate the association between radial styloid changes, pain severity, symptom duration, and clinical outcomes in patients with De Quervain’s Tenosynovitis. Materials and Methods: The study involved 32 participants with De Quervain’s Tenosynovitis, collecting data on age, symptom duration, and pain severity. Clinical assessments included pain presence, tenderness, swelling, and range of motion restriction. Imaging findings, such as radial styloid abnormalities and tendon sheath inflammation, were analyzed. Predictors of pain severity and symptom duration were assessed using descriptive statistics and multiple regression models. Results: The mean age of participants was 45.84 years (standard deviation (SD) = 11.50), with a mean symptom duration of 26.97 weeks (SD = 15.18) . The mean Visual Analog Scale (VAS) score was 4.87 (SD = 2.83) . Pain presence was reported in 93.75% of participants. Regression analysis indicated that tendon sheath inflammation and age exhibited trends toward significance in predicting VAS scores (P = 0.095, P = 0.072, respectively) . Magnetic resonance imaging signal changes showed near‑significance in predicting symptom duration (P = 0.055) . No significant correlation was found between symptom duration and pain severity (r = 0.00, P = 0.982) . Conclusion: De Quervain’s Tenosynovitis is characterized by pain‑related symptoms, with structural abnormalities and imaging findings showing variable associations with symptom severity and duration. Keywords: De Quervain’s tenosynovitis, musculoskeletal disorders, pain severity, radial styloid changes, symptom duration Introduction De Quervain’s Tenosynovitis is causing inflammation of tendons a wrist disorder due to mechanical overuse, affecting repetitive wrist movements, with potential intrinsic tendon degeneration contributing to its pathophysiology.[1] De Quervain’s Tenosynovitisis a wrist condition characterized by pain, swelling, and tenderness, often accompanied by imaging modalities like ultrasonography and Magnetic resonance imaging (MRI) .[2] | Access this article online | | | --- | --- | | Quick Response Code:
| Website: [https://journals.lww.com/jpbs](https://journals.lww.com/jpbs) | | | DOI: 10.4103/jpbs.jpbs_1303_25 | Research indicates that osseous changes in the radialstyloid may influence symptom severity and treatment response in patients with De Quervain’s Tenosynovitis.[3] The study aims to evaluate the association between these changes, pain severity, and clinical outcomes, potentially improving diagnostic accuracy and treatment strategies. | Address for correspondence: Dr. Suriya P. Raja, Department of Orthopaedics, SRM Medical College Hospital and Research Centre, Chennai, Tamil Nadu, India.
E‑mail: [sr4764@srmist.edu.in](sr4764@srmist.edu.in) | | --- | | This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License (

FAQs

What was the study aim regarding radial styloid changes?

To evaluate the association between radial styloid changes, pain severity, symptom duration, and clinical outcomes in patients with De Quervain’s tenosynovitis.

How many participants were included and what were the key assessments?

The study included 32 participants. Assessments included clinical evaluation of pain, tenderness, swelling, and range-of-motion restriction, alongside imaging findings such as radial styloid abnormalities and tendon sheath inflammation.

Did symptom duration correlate with pain severity?

No significant correlation was found between symptom duration and pain severity (r = 0.00, P = 0.982).

Which factors showed trends toward predicting pain severity or duration?

Regression analysis showed trends toward significance for tendon sheath inflammation and age in predicting VAS scores, while MRI signal changes showed near-significance in predicting symptom duration.

Sep 30, 2026

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