CHST Infliximab (Remicade or Biosimilar) - Infusion Therapy Plan (Neurology)

Q: How is hypotension defined before starting infliximab infusion?

Hypotension is defined using age-based systolic blood pressure thresholds (e.g., 1 month to 1 year: SBP < 70; 11 to 17 years: SBP < 90) or a drop of more than 30% from baseline. Baseline SBP times 0.7 indicates the hypotension cutoff value.

Q: What are the pregnancy test requirements before infusion for female patients over 10?

Only one pregnancy test is needed based on facility capability. A urine, STAT, one-time pregnancy test is required for females > 10 years old; if positive, do NOT infuse and contact the ordering provider.

Sep 26, 2026

Uploaded by Marglet

CHST infliximab infusion therapy plan (neurology) for children, specifying baseline demographics and required orders across the full treatment course. The plan covers therapy duration review at least annually, admit and nursing orders including hypotension thresholds and TB screening, and pregnancy testing requirements for females over 10 with instructions to withhold infusion if positive. It lists IV access guidance, topical lidocaine options for procedural comfort, pre-procedure laboratory intervals, and acetaminophen pre-medicating instructions, with a key of medical abbreviations.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages6

Reading Time15 min

AccessFree to download

Baseline and Therapy Course Instructions

Orders for Each Therapy (Admit, Nursing, IV Start)

Hypotension Definition and Nursing Communication

Pregnancy Testing Requirements

Nursing Orders (Continued)

Topical Anesthesia Options

Pre-Procedure Labs

Pre-Medications

*PHYO* PHYO CMC85137-002NS Rev. 11/2021 CHILDREN'S HEALTH Page 1 of 6 Patient Name: Date of Birth: CHST INFLIXIMAB (REMICADE or BIOSIMILAR) INFUSION THERAPY PLAN (NEUROLOGY) Baseline Patient Demographic To be completed by the ordering provider. Diagnosis: NKDA-No Known Drug Allergies Height: cm Weight: kg Body Surface Area: (m2) Allergies: Therapy Plan orders extend over time (several visits) including recurring treatment. Please specify the following regarding the entire course of therapy: Duration of treatment: weeks months unknown Treatment should begin: as soon as possible (within a week) within the month **Plans must be reviewed / re-ordered at least annually. ** ORDERS TO BE COMPLETED FOR EACH THERAPY ADMIT ORDERS 􀀹 Height and weight ~~􀀹~~ Vital signs HYPOTENSION DEFINED ADMIT ~~􀀹~~ Nursing communication Prior to starting infusion, please determine the patient's threshold for hypotension as defined by the following parameters. This information will be needed in the event of an infusion reaction. Hypotension is defined as follows: 1 month to 1 year-systolic blood pressure (SBP) less than 70 1 year to 11 years-systolic blood pressure (SBP) less than 70 + (2 x age in years) 11 years to 17 years-systolic blood pressure (SBP) less than 90 OR any age-systolic blood pressure (SBP) drop of more than 30% from baseline. Baseline systolic blood pressure (SBP) x 0.7 = value below defined as hypotension. PREGNANCY TESTS AT DALLAS AND PLANO Nursing communication Only one pregnancy test is necessary, based on facility capabilities. Please utilize the lab that is available per facility. Patient requires a pregnancy test (based on organizational policy, female patients over 10 require a pregnancy test) Pregnancy test, urine-POC STAT, ONE TIME, for females > 10 years old. If positive, do NOT infuse and contact the ordering provider. Gonodotropin chorionic (HCG) urine STAT, ONE TIME, unit collect, for females > 10 years old. If positive, do NOT infuse and contact the ordering provider. NURSING ORDERS 􀀹 Nursing communication Confirm TB test is negative within last year, if no test or positive, contact ordering provider. IV START NURSING ORDERS ~~􀀹~~ Insert peripheral IV / Access IVAD Place PIV if needed or access IVAD if available lidocaine 1% BUFFERED (J-TIP LIDOCAINE) 0.2 mL, INTRADERMAL, PRN when immediate procedure needed when procedure will take about 1 minute patient / family preference for procedure Administration Instructions: NOTE: Do not use this medication in patients with bleeding disorders, platelets < 20,000, or in patients taking anticoagulants, when accessing implanted ports or using a vein that will be utilized for chemotherapy administration, nor for pre-term infants or neonates. Key: cm = centimeter; HCG = Gonodotropin chorionic; IV = intravenous; IVAD = implantable venous access device; kg = kilogram; m² = square meters; mg = milligram; mL = milliliter; mL / hr = milliliters per hour; mOsm / L = milliosmole per liter; NKDA = no known drug allergies; pH = hydrogen ion concentration; PIV = peripheral intravenous; POC = point of care; PRN = as needed; RTA= ready to administer; STAT = immediately; TB = tuberculosis *PHYO* PHYO CMC85137-002NS Rev. 11/2021 CHILDREN'S HEALTH Patient Name: Date of Birth: CHST INFLIXIMAB (REMICADE or BIOSIMILAR) INFUSION THERAPY PLAN (NEUROLOGY) Page 2 of 6 ORDERS TO BE COMPLETED FOR EACH THERAPY NURSING ORDERS, CONTINUED Please select all appropriate therapy lidocaine-prilocaine (EMLA) cream TOPICAL, PRN when more than 60 minutes are available before procedure when procedure will take more than 1 hour patient / family preference for procedure Administration Instructions: NOTE: In children < 3 months of age, or < 5 kg in weight, maximum application time is 1 hour. lidocaine-tetracaine (SYNERA) patch TOPICAL, PRN when 20-30 minutes are av

FAQs

How is hypotension defined before starting infliximab infusion?

Hypotension is defined using age-based systolic blood pressure thresholds (e.g., 1 month to 1 year: SBP < 70; 11 to 17 years: SBP < 90) or a drop of more than 30% from baseline. Baseline SBP times 0.7 indicates the hypotension cutoff value.

What are the pregnancy test requirements before infusion for female patients over 10?

Only one pregnancy test is needed based on facility capability. A urine, STAT, one-time pregnancy test is required for females > 10 years old; if positive, do NOT infuse and contact the ordering provider.

Which pre-procedure labs and pre-medications are specified in the plan?

Pre-procedure labs include CBC with differential and hepatic function panel, both with intervals every 12 weeks and deferred until after the 3rd infusion, then every 3 months. Acetaminophen is given 30 minutes prior (suspension or tablet, 15 mg/kg max 650 mg), with instruction to administer only one formulation.

Sep 26, 2026

Uploaded by Marglet