CHAPTER 41—EPIDEMIOLOGY HEALTH - SUBCHAPTER 41A—COMMUNICABLE DISEASE CONTROL - SECTION .0100—COMMUNICABLE DISEASE CONTROL

Sep 26, 2026

Lists reportable communicable diseases and conditions requiring timely notification in North Carolina once a disease or condition is reasonably suspected, referencing state statutes and the applicable subchapter. Specifies reporting deadlines for numerous infections (e.g., AIDS, influenza causing death, cholera, mumps, tuberculosis) and defines what constitutes confirmed human immunodeficiency virus (HIV) infection. Further requires laboratories to report isolation or specific identification of specified organisms or products from human clinical specimens, including pathogens such as hantaviruses, hemorrhagic fever viruses, anthrax, and Lyme-associated organisms.

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CHAPTER 41—EPIDEMIOLOGY HEALTH

SUBCHAPTER 41A—COMMUNICABLE DISEASE CONTROL

SECTION .0100—COMMUNICABLE DISEASE CONTROL

10A NCAC 41A .0101 REPORTABLE DISEASES AND CONDITIONS

CHAPTER 41—EPIDEMIOLOGY HEALTH SUBCHAPTER 41A—COMMUNICABLE DISEASE CONTROL SECTION .0100—COMMUNICABLE DISEASE CONTROL 10A NCAC 41A .0101 REPORTABLE DISEASES AND CONDITIONS (a) The following is a list of communicable diseases and communicable conditions which shall be reported within the time period specified after the disease or condition is reasonably suspected to exist pursuant to Article 6 of Chapter 130A of the North Carolina General Statutes and this Subchapter: (1) acquired immune deficiency syndrome (AIDS)—24 hours; (2) acute flaccid myelitis—7 days; (3) anaplasmosis—7 days; (4) anthrax—immediately; (5) arboviral infection, neuroinvasive—7 days; (6) babesiosis—7 days; (7) botulism—immediately; (8) brucellosis—7 days; (9) campylobacter infection — 24 hours; (10) Candida auris—24 hours; (11) Carbapenemase—producing organisms (CPO)—24 hours; (12) chancroid—24 hours; (13) chikungunya virus infection—24 hours; (14) chlamydial infection (laboratory confirmed)—7 days; (15) cholera—24 hours; (16) Creutzfeldt Jakob disease—7 days; (17) cronobacter infection, invasive, in individuals less than 12 months of age—24 hours; (18) cryptosporidiosis—24 hours; (19) cyclosporiasis—24 hours; (20) dengue—7 days; (21) diphtheria—24 hours; (22) Escherichia coli, shiga toxin—producing infection—24 hours; (23) ehrlichiosis—7 days; (24) foodborne disease, including Clostridium perfringens, staphylococcal, Bacillus cereus, and other and unknown causes—24 hours; (25) gonorrhea—24 hours; (26) granuloma inguinale—24 hours; (27) Haemophilus influenzae, invasive disease—24 hours; (28) Hantavirus infection—7 days; (29) Hemolytic—uremic syndrome—24 hours; (30) Hemorrhagic fever virus infection—immediately; (31) hepatitis A—24 hours; (32) hepatitis B—24 hours; (33) hepatitis B carriage—7 days; (34) hepatitis C, acute—7 days; (35) human immunodeficiency virus (HIV) infection confirmed—24 hours; (36) influenza virus infection causing death—24 hours; (37) legionellosis—7 days; (38) leprosy—7 days; (39) leptospirosis—7 days; (40) listeriosis—24 hours; (41) Lyme disease—7 days; (42) Lymphogranuloma venereum—7 days; (43) malaria—7 days; (44) measles (rubeola)—immediately; (45) meningitis, pneumococcal—7 days; (46) meningococcal disease—24 hours; (47) Middle East respiratory syndrome (MERS)—24 hours; (48) mpox—24 hours; (49) mumps—7 days; (50) nongonococcal urethritis—7 days; (51) novel coronavirus infection causing death—24 hours; (52) novel coronavirus infection—immediately; (53) novel influenza virus infection—immediately; (54) plague—immediately; (55) paralytic poliomyelitis—24 hours; (56) pelvic inflammatory disease—7 days; (57) psittacosis—7 days; (58) Q fever—7 days; (59) rabies, human—24 hours; (60) rubella—24 hours; (61) rubella congenital syndrome—7 days; (62) salmonellosis—24 hours; (63) salmonella typhi infection—24 hours; (64) salmonella paratyphi infection—24 hours; (65) severe acute respiratory syndrome (SARS)—24 hours; (66) shigellosis—24 hours; (67) smallpox—immediately; (68) spotted fever rickettsiosis—7 days; (69) Staphylococcus aureus with reduced susceptibility to vancomycin—24 hours; (70) streptococcal infection, Group A, invasive disease—7 days; (71) syphilis—24 hours; (72) tetanus—7 days; (73) toxic shock syndrome—7 days; (74) trichinosis—7 days; (75) tuberculosis—24 hours; (76) tularemia—immediately; (77) typhus, epidemic (louse—borne)—7 days; (78) vaccinia—24 hours; (79) varicella—24 hours; (80) vibrio infection (other than cholera)—24 hours; (81) whooping cough—24 hours; (82) yellow fever—7 days; and (83) zika virus—24 hours. (b) For purposes of reporting, "confirmed human immunodeficiency virus (HIV) infection" is defined as a positive virus culture, repeatedly reactive EIA antibody test confirmed by western blot or indirect immunofluorescent antibody test, pos

FAQs

What reporting timeframe applies to suspected communicable diseases and conditions under 10A NCAC 41A .0101?

Reportable diseases and conditions must be reported within the specified time period after the disease or condition is reasonably suspected to exist under the referenced statute and subchapter rules.

How does the rule define “confirmed human immunodeficiency virus (HIV) infection”?

Confirmed HIV infection is defined as a positive virus culture, repeatedly reactive EIA with western blot confirmation or indirect immunofluorescent antibody test, positive nucleic acid detection (NAT), or other confirmed testing approved by the Director of the State Public Health Laboratory on or after February 1, 1990.

What additional laboratory reporting is required beyond general laboratory reports?

In addition to laboratory reports for Mycobacterium tuberculosis, Neisseria gonorrhoeae, and syphilis, laboratories must report isolation or other specific identification of listed organisms or their products from human clinical specimens according to the referenced rule.

Sep 26, 2026

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