Changes in Choroidal Thickness and Its Effects on the Refractive Outcome After Surgical Treatment of Cataract Using Phacoemulsification Combined With Goniosynechialysis in Patients With Primary Angle Closure/Glaucoma

Sep 29, 2026

Uploaded by Mary Man

This research evaluates how choroidal thickness (CT) changes relate to refractive outcomes after cataract surgery in patients with primary angle-closure/angle-closure glaucoma (PAC/PACG) using phacoemulsification combined with goniosynechialysis (Phaco-GSL). Seventy-nine eyes from 54 patients underwent serial follow-ups, with intraocular pressure, best-corrected visual acuity, and CT measured preoperatively and at 1 week and 1, 3, and 6 months. CT showed an initial postoperative rise followed by a gradual decline toward baseline. CT parameters correlated with IOP, axial length, and mean deviation, while CT changes were associated with increased mean refractive error, offering insight into refractive shifts after surgery.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages9

Reading Time23 min

AccessFree to download

Purpose

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1. Introduction

Wiley Journal of Ophthalmology Volume 2025, Article ID 7173240, 9 pages [https://doi.org/10.1155/joph/7173240](https://doi.org/10.1155/joph/7173240) Research Article Changes in Choroidal Thickness and Its Effects on the Refractive Outcome After Surgical Treatment of Cataract Using Phacoemulsification Combined With Goniosynechialysis in Patients With Primary Angle Closure/Glaucoma Siqi Guo, Hao You, Zhen Jiang, Kaihui Chen, Ruifeng Li , and Ling Yu Department of Ophthalmology, Army Medical Center of PLA, Army Medical University, Chongqing 400042, China Correspondence should be addressed to Ruifeng Li; 1009261172@qq.com and Ling Yu; [oculistlingyu@hotmail.com](oculistlingyu@hotmail.com) Received 1 December 2024; Revised 19 October 2025; Accepted 14 November 2025 Academic Editor: Dirk Sandner Copyright © 2025 Siqi Guo et al. Journal of Ophthalmology published by John Wiley & Sons Ltd. Tis is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. Purpose: To evaluate changes in choroidal thickness (CT) and their association with refractive outcomes after phacoemulsifcation combined with goniosynechialysis (Phaco-GSL) in patients with primary angle-closure/glaucoma (PAC/PACG) . Methods: Tis study involved 79 eyes from 54 patients with PAC/PACG who underwent Phaco-GSL. Intraocular pressure (IOP), best-corrected visual acuity (BCVA), and CT were measured preoperatively and at 1 week (W1), 1 month (M1), 3 months (M3), and 6 months (M6) postoperatively. In addition, anterior chamber depth (ACD), axial length (AL), visual feld mean deviation (MD), and mean refractive error (MRE) were recorded preoperatively and at the fnal follow-up visit. Correlations between ocular biometric parameters and MRE were analyzed using appropriate statistical methods. Results: Within 6 months after Phaco-GSL, CT measured at 13 predefned locations showed an initial postoperative increase, followed by a gradual decline, eventually returning to baseline levels. IOP decreased at W1 and stabilized at M6 . In addition, subfoveal choroidal thickness (SFCT) was negatively correlated with IOP preoperatively (p < 0.05) and AL both preoperatively and at M6 (p < 0.01) but positively related to MD at M6. Moreover, CT changes were positively correlated with MRE (p < 0.05), while changes in ACD, AL, and IOP were not associated with MRE (all, p > 0.05) . Conclusion: Tese fndings suggest that CT initially increases and then decreases over a 6-month period following Phaco-GSL. CTis associated with IOP, AL, and MD reductions. Furthermore, CT changes are associated with an increase in MRE, ofering valuable insights into the refractive shifts in PAC/PACG patients after Phaco-GSL. Keywords: changes and efects; choroidal thickness; PAC/PACG; Phaco-GSL 1. Introduction Primary angle-closure (PAC) and primary angle-closure glaucoma (PACG) are subtypes of glaucoma, with particularly high prevalence in Asia, especially in China [1, 2] . Te precise mechanism underlying PAC has not been fully elucidated. Some scholars propose that the expansion of thechoroid plays an important role in angle closure. Specifcally, choroidal thickening may elevate posterior segment pressure, creating a transvitreal pressure gradient that pushes the lens–iris diaphragm anteriorly, resulting in anterior chamber shallowing and narrowing of the iridocorneal angle [3] . Additionally, healthy individuals with shallow anterior chambers or short axial length (AL) are susceptible to acute angle-closure attacks [4]. Terefore, the exact mechanism for the onset of PAC/PACG deserves further attention. Studies have shown that after glaucoma surgery, a decrease in intraocular pressure (IOP) may lead to an increase in choroidal blood volume, contributing to a decrease in ALand an increased choroidal thickness (CT) [5] . However, the 2 Journal of

FAQs

What is the purpose of this study?

To evaluate CT changes and their association with refractive outcomes after Phaco-GSL in patients with PAC/PACG.

How were CT and ocular parameters measured?

IOP, BCVA, and CT were measured preoperatively and at multiple postoperative time points (1 week, 1 month, 3 months, 6 months). Additional biometric measures such as ACD and axial length were also recorded at baseline and at the final follow-up.

What were the main findings about CT and refractive outcomes?

CT increased shortly after surgery and then gradually decreased, returning toward baseline by 6 months. CT changes were associated with increased mean refractive error, while changes in ACD, axial length, and IOP were not associated with mean refractive error.

Sep 29, 2026

Uploaded by Mary Man