AQA GCSE Combined Science - Higher - Advance Information of Assessed Content 2022

Sep 5, 2026

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AQA GCSE Combined Science Higher Tier Paper 1 biology, chemistry and physics focus areas for 2022 are outlined through specification points and key concepts. The guide highlights what will be assessed, including cell division, animal tissues and organs, required practicals such as tests for carbohydrates, lipids and proteins, and investigating pH effects on amylase and photosynthesis. Revision guidance also notes that omitted points may still appear in multiple choice or linked questions, while a list of specification areas not assessed is provided.

LanguageEnglish

CategoryExam

FormatPDF

Pages20

Reading Time50 min

AccessFree to download

Biology Paper 1 (Higher Tier)

Assessed specification focus

Required practicals

Specification points not assessed

AQA GCSE Combined Science Trilogy: Higher Advance Information of Assessed Content 2022 Link to specification: [https://fi](https://fi)[lestore.aqa.org.uk/resources/science/specifications/AQA-8464-SP-2016.PDF](lestore.aqa.org.uk/resources/science/specifications/AQA-8464-SP-2016.PDF) Link to advance information document: [https://fi](https://fi)[lestore.aqa.org.uk/content/summer-2022/AQA-8464-AI-22.PDF](lestore.aqa.org.uk/content/summer-2022/AQA-8464-AI-22.PDF) Link to revised Physics equation sheet: [https://fi](https://fi)[lestore.aqa.org.uk/resources/science/AQA-8464-8465-ES-INS.PDF](lestore.aqa.org.uk/resources/science/AQA-8464-8465-ES-INS.PDF) AQA GCSE Combined Science: Higher Tier Paper 1 (biology, chemistry, physics) B io logy Paper 1-H These specification points will be the major focus of this paper. Exam date: 17th May All other specification points from B1, other those on these pages that are not explicitly omitted, may still be assessed in multiple choice questions/linked to a previous answer, so cannot be completely ignored in your revision | Spec point | Concepts | Bitesize | YouTube | | --- | --- | --- | --- | | 4.1.2 Cell Division | • How DNA is arranged as chromosomes
• Series of stages in the cell cycles inc. mitosis
• Definition and uses of stem cells | [https://www.bbc.co.uk/bitesize](https://www.bbc.co.uk/bitesize)[ ](https://www.bbc.co.uk/bitesize)[/guides/z2kmk2p/revision/2](/guides/z2kmk2p/revision/2)
[https://www.bbc.co.uk/bitesize](https://www.bbc.co.uk/bitesize)[ ](https://www.bbc.co.uk/bitesize)[/guides/z2kmk2p/revision/3](/guides/z2kmk2p/revision/3) | [https://www.youtube.com/wat](https://www.youtube.com/wat)[ch?v=RHyZVmbiA78](ch?v=RHyZVmbiA78)
[https://www.youtube.com/wat](https://www.youtube.com/wat)[ch?v=Kh27eyjxvYM&t=24s](ch?v=Kh27eyjxvYM&t=24s) | | 4.2.2 Animal tissues, organs and organ systems | • Functions of tissues and organs in the digestive system
• Digestive enzymes
• Functions of tissues and organs in the circulatory system
• Pathway of blood through the heart
• Adaptations of components of the blood
• Risk factors of non-communicable diseases
• Explain the cause of CHD
• Evaluate the advantages and disadvantages of treating cardiovascular diseases by drugs, mechanical devices or transplant | [https://www.bbc.co.uk/bitesize](https://www.bbc.co.uk/bitesize)[ ](https://www.bbc.co.uk/bitesize)[/guides/z89mk2p/revision/1](/guides/z89mk2p/revision/1)
[https://www.bbc.co.uk/bitesize](https://www.bbc.co.uk/bitesize)[ ](https://www.bbc.co.uk/bitesize)[/guides/zsncsrd/revision/1](/guides/zsncsrd/revision/1) | [https://www.youtube.com/wat](https://www.youtube.com/wat)ch?v=4ui4oSHHnzA
[https://www.youtube.com/wat](https://www.youtube.com/wat)[ch?v=VLK2wANjQm0](ch?v=VLK2wANjQm0)
[https://www.youtube.com/wat](https://www.youtube.com/wat)[ch?v=bpYaKM2hVFY](ch?v=bpYaKM2hVFY)
GCSE Biology-Why Do We Get Heart Disease and How to Treat It? -Cardiovascular Disease (CVD) \#20 – YouTube | | Required practical 3:
test for carbohydrates, lipids and proteins | • Reagent and positive result for carbohydrates, proteins and lipids | [https://www.bbc.co.uk/bitesize](https://www.bbc.co.uk/bitesize)[ ](https://www.bbc.co.uk/bitesize)[/guides/z89mk2p/revision/3](/guides/z89mk2p/revision/3) | [https://www.youtube.com/wat](https://www.youtube.com/wat)[ch?v=SqWTJWOBww4](ch?v=SqWTJWOBww4) | | Required Practical 4
investigate the effect of pH on the rate of reaction of amylase enzyme. | • Action of enzymes
• Describe and explain the effect of extreme pH on rate of enzymes
• Testing for starch
• Identify independent, dependent, control variables
• How to measure the dependent variable
• Method
• Analysing results | Required practical activityAnimal organisation-digestion-AQA-GCSE Combined Science Revision-AQA Trilogy-BBC Bitesize | GCSE Science Revision Biology"Required Practical 5: Effect of pH on Amylase" – YouTube
Enzymes-GCSE

FAQs

Which biology specification points are the major focus for this Higher Tier Paper 1?

The document lists assessed specification points such as cell division and animal tissues, organs and organ systems, along with their associated core concepts.

What required practicals are included in the assessed content?

Included practicals cover testing for carbohydrates, lipids and proteins, and investigating the effect of pH on the rate of reaction of the amylase enzyme, plus a practical on the effect of light intensity on the rate of photosynthesis.

Are specification points not listed as assessed completely ignored in the exam?

No. The document states that other specification points not explicitly omitted may still be assessed in multiple choice questions or linked to previous answers.

Sep 5, 2026

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