Advances in gastrointestinal endoscopy: A comprehensive review of innovations in cancer diagnosis and management

Sep 23, 2026

The field of gastroenterology has advanced rapidly as flexible endoscopes have become broadly available, enabling faster, less invasive, and more affordable diagnosis and treatment. New endoscopic technologies—magnification endoscopy, narrow-band imaging, endoscopic ultrasound with biopsy, and increasingly artificial intelligence–enhanced systems—improve recognition and detection of neoplasms and sub-epithelial tumors. This review outlines recent developments in endoscopic procedures, techniques, and devices used to diagnose and manage gastrointestinal cancer.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages19

Reading Time48 min

AccessFree to download

Introduction

Advances in endoscopic technologies for GI cancer

Upper GI endoscopy

Key diagnostic and therapeutic techniques

| W | J | G | E | World Journal of
Gastrointestinal Endoscopy | | --- | --- | --- | --- | --- | Submit a Manuscript: [https://www.f6publishing.com](https://www.f6publishing.com) World J Gastrointest Endosc 2025 May 16; 17(5): 105468 DOI: 10.4253/wjge.v17.i5.105468 ISSN 1948-5190 (online) EVIDENCE REVIEW Advances in gastrointestinal endoscopy: A comprehensive review of innovations in cancer diagnosis and management Mohammed Abusuliman, Taher Jamali, Tobias E Zuchelli Specialty type: Gastroenterology and hepatology Provenance and peer review: Invited article; Externally peer reviewed. Peer-review model: Single blind Peer-review report’s classification Scientific Quality: Grade A, Grade B Novelty: Grade B, Grade C Creativity or Innovation: Grade B, Grade C Scientific Significance: Grade B, Grade B P-Reviewer: Budaya TN; Zhang T Received: January 23, 2025 Revised: March 26, 2025 Accepted: April 15, 2025 Published online: May 16, 2025 Processing time: 109 Days and 5 Hours Mohammed Abusuliman, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI 48202, United States Taher Jamali, Tobias E Zuchelli, Department of Gastroenterology, Henry Ford Hospital, Detroit, MI 48202, United States Corresponding author: Mohammed Abusuliman, MD, Department of Internal Medicine, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, [United States.](United States. dr.salah.ma@gmail.com)[ dr.salah.ma@gmail.com](United States. dr.salah.ma@gmail.com) Abstract The field of gastroenterology has experienced revolutionary advances over the past years, as flexible endoscopes have become widely accessible. In addition to enabling faster, less invasive, and more affordable treatment, flexible endoscopeshave greatly improved the detection and endoscopic screening of malignancies and prevented many cancer-related deaths. The development and clinical application of new diagnostic endoscopic technologies, such as magnification endoscopy, narrow-band imaging, endoscopic ultrasound with biopsy, and more recently, artificial intelligence enhanced technologies, have made the recognition and detection of various neoplasms and sub-epithelial tumors more possible. This review demonstrates the latest advancements in endoscopic procedures, techniques, and devices applied in the diagnosis and management of gastrointestinal cancer. Key Words: Endoscopy; Colonoscopy; Endoscopic ultrasound; Cancer diagnosis; Therapeutic endoscopy; Gastroenterology; Endoscopic submucosal dissection ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. WJGE [https://www.wjgnet.com](https://www.wjgnet.com) 1 May 16, 2025 Volume 17 Issue 5 Abusuliman M et al. Innovations in gastrointestinal endoscopy for cancer Core Tip: This review comprehensively explores the latest advancements in gastrointestinal (GI) endoscopy, highlighting innovations in diagnostic and therapeutic techniques for GI cancers. Cutting-edge technologies such as magnification endoscopy, narrow-band imaging, endoscopic ultrasound with fine-needle biopsy, and artificial intelligence-enhanced methods are transforming cancer detection, staging, and management. Endoscopic approaches like submucosal dissection and mucosal resection are improving outcomes for premalignant and malignant lesions. These developments underscore the pivotal role of endoscopy in reducing morbidity, mortality, and healthcare costs associated with GI cancers. Citation: Abusuliman M, Jamali T, Zuchelli TE. Advances in gastrointestinal endoscopy: A comprehensive review of innovations in cancer diagnosis and management. World J Gastrointest Endosc 2025; 17(5): 105468 URL: [https://www.wjgnet.com/1948-5190/full/v17/i5/105468.htm](https://www.wjgnet.com/1948-5190/full/v17/i5/105468.htm) DOI: [https://dx.doi.org/10.4253/wjge.v17.i5.105468](https://dx.doi.org/10.4253/wjge.v17.i5.105468) INTRODUCTION The field of gastroenterology has undergone a

FAQs

What has driven recent advances in gastrointestinal endoscopy?

Expanded access to flexible endoscopes and rapid growth of endoscopic technologies have transformed diagnosis and staging of gastrointestinal cancers and improved clinical management.

Which diagnostic technologies are highlighted in the review?

The review emphasizes magnification endoscopy, narrow-band imaging, endoscopic ultrasound with biopsy, and artificial intelligence–enhanced technologies for better detection and recognition of tumors.

How does endoscopy contribute to management beyond diagnosis?

Endoscopic approaches such as endoscopic submucosal dissection and mucosal resection improve outcomes for premalignant and malignant lesions, while endoscopic ultrasound supports therapeutic-oriented staging and biopsy.

Sep 23, 2026

Uploaded by Quinn Holloway