A NUDGE-BASED CAMPAIGN FOR DEMENTIA PREVENTION OUTCOMES - A PRAGMATIC CLUSTER-RANDOMIZED TRIAL

Sep 29, 2026

Although dementia prevention is a global priority, few interventions have been effectively translated into public health and community settings. This study evaluated a nudge-based Alzheimer’s disease prevention campaign in older adults and healthcare providers through a pragmatic cluster-randomized trial in seven senior centers in Chile. Adults aged 60+ with cognitive impairment but no dementia were assigned to intervention or control. After six months, intervention centers showed improved cognitive healthy behaviors, cognitive outcomes, and provider practices.

LanguageEnglish

CategoryResearch & Report

FormatPDF

Pages1

Reading Time3 min

AccessFree to download

Abstract citation ID

igaf122.4279

Study objective

Translation to public health and community settings

Trial design

Pragmatic cluster-randomized trial in senior centers

Intervention

Nudge-based campaign delivered via posters, brochures, and web content

Outcomes

Cognitive behaviors and cognitive performance

Provider practices

Innovation in Aging, 2025, Vol. 9, No. S2 1283 intervention participants (n =101) demonstrated a 95.4% greater increase in cognitive healthy behaviors than controls (n = 110), significantly higher memory and executive function scores, anda lower prevalence of mild-to-moderate cognitive impairment. They were also more likely to report greater knowledge of AD prevention, to have engaged in discussions with providers about dementia risk reduction, and to have received referrals for managing risk factors. Embedding nudge-based messaging into senior centers improved dementia prevention behaviors, cognitive outcomes, and provider practices. These findings highlight the promise of low-cost, scalable strategies for advancing dementia prevention in real-world settings. SESSION 9035 (PAPER) LATE BREAKING: ALZHEIMER’S DISEASE, INCLUDING ALZHEIMER’S DISEASE—RELATED DEMENTIAS VIII Abstract citation ID: igaf122.4279 A NUDGE-BASED CAMPAIGN FOR DEMENTIA PREVENTION OUTCOMES: A PRAGMATIC CLUSTER-RANDOMIZED TRIAL Jose Aravena1, Hugo Castro2, Ronald Poblete2, Maria Aravena2, Marilu Budinich2, Patricio Fuentes3, Cecilia Albala4, and Becca Levy5, 1. Yale University, New Haven, Connecticut, United States, 2. CULTIVAMENTE, Santiago, Region Metropolitana, Chile, 3. Hospital Clinico Universidad de Chile, Santiago, Region Metropolitana, Chile, 4. INTA, University of Chile, Santiago, Region Metropolitana, Chile, 5. Yale School of Public Health, New Haven, Connecticut, United States Although dementia prevention is a global priority, few interventions have been successfully translated into public health and community settings. To address this gap, we evaluated the effectiveness of a nudge-based Alzheimer’s disease (AD) prevention campaign on dementia prevention outcomes in older adults and healthcare providers. A pragmatic cluster-randomized trial was conducted in seven senior centers in Chile with adults aged ≥60 years who had cognitive impairment but no dementia. Centers were randomized to intervention (n = 3) or control (n = 4) . All participants received usual care, including twice-weekly group activities (physical, cognitive, and social) and healthcare provider dementia training. Intervention centers additionally implemented CULTIVAMENTE, a nudge-based awareness campaign delivered through posters, brochures, and web content. We hypothesized that the intervention would improve cognitive healthy behaviors, cognitive performance (memory, executive function, and prevalence of mild-to-moderate cognitive impairment), and provider practices (AD prevention discussions and referrals). Intention-totreat analyses using linear mixed models and generalized estimating equations confirmed these predictions. After six months,

FAQs

What problem does the study address?

Dementia prevention is a global priority, but few interventions have been successfully translated into public health and community settings.

How was the trial designed and where was it conducted?

A pragmatic cluster-randomized trial was conducted in seven senior centers in Chile with adults aged 60 years and older.

What was the intervention and what outcomes were expected?

Intervention centers implemented a nudge-based awareness campaign via posters, brochures, and web content, aiming to improve cognitive healthy behaviors, cognitive performance, and provider practices such as prevention discussions and referrals.

Sep 29, 2026

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