2023 European Society of Cardiology guidelines for the management of infective endocarditis - Statement of endorsement by the NVVC

Sep 30, 2026

Uploaded by Theodore

This review evaluates the 2023 European Society of Cardiology (ESC) guidelines for the management of infective endocarditis (IE) and provides practice-relevant insights for the Netherlands. The multidisciplinary IE Working Group assessed all ESC recommendations and concluded that most could be endorsed, while incorporating refinements suited to Dutch clinical care. Key endorsed updates include a refined antibiotic prophylactic regimen, guidance for suspected blood culture-negative IE, and strengthened emphasis on the Endocarditis Team’s role.

LanguageEnglish

CategoryHealthcare

FormatPDF

Pages11

Reading Time28 min

AccessFree to download

Abstract

Endorsement

Statement of endorsement by the NVVC

Keywords

Introduction

NVVC Endorsements Neth Heart J (2026) 34:7–17 [https://doi.org/10.1007/s12471-025-0201](https://doi.org/10.1007/s12471-025-0201)1-9 2023 European Society of Cardiology guidelines for the management of infective endocarditis Statement of endorsement by the NVVC Short version Annelot J. L. Peijster · Cees van Nieuwkoop · Ruud W. M. Keunen · Susanne Felix · Berend J. van Welzen · Ilse J. E. Kouijzer · C. H. Edwin Boel · Nelianne J. Verkaik · Ka Yan Lam · Robert J. M. Klautz · Andor W. J. M. Glaudemans · Ricardo P. J. Budde · Alexander H. Maass · Reinoud E. Knops · Otto Kamp · Wilco Tanis Received: 16 September 2025 / Accepted: 2 December 2025 / Published online: 18 December 2025 © The Author(s) 2025 Abstract This review evaluates the 2023 European Society of Cardiology (ESC) guidelines for the management of infective endocarditis (IE) and offers insights into topics particularly relevant to clinical practice in the Netherlands. The multidisciplinary IE Working Group assessed all ESC recommendations and concluded that the majority could be endorsed, | Endorsement The full version of this paper was initiated and endorsed by the Dutch Society of Cardiology (Nederlandse Vereniging voor Cardiologie, NVVC) . In addition, it underwent ﬁnal-stage review and approval by the Dutch Society of Internal Medicine (Nederlandse Internisten Vereniging, NIV), the Netherlands Society for Cardiothoracic Surgery (Nederlandse Vereniging voor Thoraxchirurgie, NVT), the Dutch Society of Radiology (Nederlandse Vereniging voor Radiologie, NVvR), and the ENDOCOR Working Group. | | --- | | Statement This article presents a condensed version of the complete IE endorsement paper, focusing on selected aspects only. For comprehensive coverage, readers are referred to the full online version ([https://doi.org/10.1007/](https://doi.org/10.1007/)[ ](https://doi.org/10.1007/)[s12471-025-02010-w](s12471-025-02010-w)) . | | Supplementary Information The online version of this article ([https://doi.org/10.1007/s12471-025-02011-9](https://doi.org/10.1007/s12471-025-02011-9)) contains supplementary material, which is available to authorized users. | A. J. L. Peijster (􀀂) · R. E. Knops · O. Kamp · W. Tanis Department of Cardiology, Amsterdam University Medical Centre, Amsterdam, The Netherlands [a.j.l.peijster@amsterdamumc.nl](a.j.l.peijster@amsterdamumc.nl) A. J. L. Peijster · W. Tanis Department of Cardiology, Haga Teaching Hospital, The Hague, The Netherlands albeit with certain modiﬁcations. The IE Working Group presents a reﬁned (and simpliﬁed) antibiotic prophylactic regimen and an updated table to guide the analysis of suspected blood culture-negative IE. Furthermore, the pivotal role of the Endocarditis Team in the management of patients with suspected and conﬁrmed IE was reafﬁrmed, along with reinforced C. van Nieuwkoop Department of Internal Medicine, Haga Teaching Hospital, The Hague, The Netherlands R. W. M. Keunen Department of Neurology, Haga Teaching Hospital, The Hague, The Netherlands S. Felix Department of Cardiology, Catharina Hospital, Eindhoven, The Netherlands B. J. van Welzen Department of Infectious Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands I. J. E. Kouijzer Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands C. H. E. Boel Department of Medical Microbiology, University Medical Centre Utrecht, Utrecht, The Netherlands N. J. Verkaik Department of Microbiology, Erasmus Medical Centre, Rotterdam, The Netherlands K. Y. Lam Department of Cardiothoracic Surgery, Catharina Hospital, Eindhoven, The Netherlands 2023 European Society of Cardiology guidelines for the management of infective endocarditis 7 NVVC Endorsements recommendations for nearly all cardiac and extracardiac imaging in these cases. Most notable, a preliminary recommendation was issued for switching to oral antibiotic therapy in patients with native valv

FAQs

What is the purpose of the NVVC endorsement statement for the 2023 ESC infective endocarditis guideline?

It provides a condensed endorsement of the 2023 ESC IE guideline tailored to topics relevant to Dutch clinical practice, including selected adjustments and emphasis areas.

Which major recommendations were assessed for endorsement by the multidisciplinary IE Working Group?

The group reviewed ESC recommendations across prevention, diagnostic criteria, multimodality imaging, oral antibiotic therapy, surgical indications, and timing, and concluded that most could be endorsed.

What key clinical roles and treatment-related updates are highlighted in the endorsed statement?

The statement reinforces the pivotal role of the Endocarditis Team, presents a refined antibiotic prophylactic regimen, and updates guidance for analysis of suspected blood culture-negative IE.

Sep 30, 2026

Uploaded by Theodore