[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-169036-en":3,"doc-seo-169036-105":30,"detail-sidebar-cat-1-en-105":96},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":11,"category_id":12,"category_name":13,"doc_title":14,"doc_description":15,"doc_content":16,"file_id":17,"file_url":18,"file_type":19,"file_size":20,"view_count":11,"is_deleted":4,"is_public":11,"is_downloadable":11,"audit_status":11,"page_count":21,"language":22,"language_code":23,"site_id":24,"html_lang":23,"table_of_contents":25,"faqs":26,"seo_title":27,"seo_description":15,"update_tm":28,"read_time":29},169036,962084925502,"Emma Mercer","https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8",1,11,"Presentations","Venous Thromboembolism Diagnosis and Management of Special Populations in Latin America - Educational Slide Sets - ASH 2022","Educational slide sets for the American Society of Hematology 2022 present venous thromboembolism (VTE) diagnosis and management guidance tailored to special populations in Latin America. The material outlines how Latin American recommendations were developed using the GRADE-ADOLOPMENT approach, including panel formation, PICO-framed clinical questions, and evidence synthesis across benefits, harms, feasibility, acceptability, accessibility, and patient values. It covers diagnostic pretest probability concepts and reviews comparative outcomes versus original ASH recommendations, including changes in guidance and strength.","Venous Thromboembolism Diagnosis and Management of Special Populations in Latin America\nEducational Slide Sets\nAmerican Society of Hematology 2022 for the Management of Venous Thromboembolism Disease\nAuthor: Dr Juan Carlos Serrano Casas, MD, Central University of Venezuela\nClínica Cancerológica de Norte de Santander (North Santander Oncology Clinic)\nClinical Practice Guidelines\nASH, ABHH, ACHO, CAHT Group, CLAHT Group, SAH, SBHH, SHU, SOCHIHEM, SOMETH, Panamenian Society of Hematology, SPH, SVH.\n2022 guidelines for venous thromboembolism diagnosis and management of Special Populations in Latin America\nIgnacio Neumann, Ariel Izcovich, Ricardo Aguilar, Guillermo León Basantes, Patricia Casais, Cecilia Colorio, Cecilia Guillermo, Pedro Garcia Lazaro, Jaime Pereira, Luis Meillon, Suely Meireles Rezende, Juan Carlos Serrano, Mario Luis Tejerina Valle, Felipe Vera, Lorena Karzulovic, Gabriel Rada, Holger Schunemann.\nGRADE-ADOLOPMENT is an explicit and systematic method for adoption, adaptation, or development of evidence-based recommendations derived from the existing GRADE-focused recommendation.\nGRADE Evidence to Decision frameworks for adoption, adaptation, and de novo development of trustworthy recommendations: GRADE-ADOLOPMENT¨ (J Clin Epidemiol. 2017 Jan; 81:101-110).\nLatin American ADOLOPMENT project\nThe Latin American ADOLOPMENT project is a pilot collaborative effort of the following institutions\nArgentinian Society of Hematology (Sociedad Argentina de Hematología, SAH), Cecilia Colorio, MD\nBolivian Society of Hematology and Hemotherapy (Sociedad Boliviana de Hematología y Hemoterapia, SBHH), Mario Luis Tejerina Valle, MD\nBrazilian Association of Hematology, Hemotherapy and Cellular Therapy (Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular, ABHH), Suely Meireles Rezende, MD PhD\nChilean Society of Hematology (Sociedad Chilena de Hematología), Jaime Pereira, MD\nPeruvian Society of Hematology (Sociedad Peruana de Hematología, SPH), Pedro García Lázaro, MD\nUruguay’s Society of Hematology (Sociedad de Hematología del Uruguay, SHU), Cecilia Guillermo, MD\nVenezuelan Society of Hematology (Sociedad Venezolana de Hematología, SVH), Juan Carlos Serrano, MD\nLatin American Cooperative for Hemostasis and Thrombosis (Grupo Cooperativo Latinoamericano de Hemostasis y Trombosis, CLAHT), Patricia Casais, MD\nMexican Association of Hematology (Asociación Mexicana de Hematología), Luis Meillon, MD\nColombian Association of Hematology and Oncology (Asociación Colombiana de Hematología y Oncología), Guillermo Basantes, MD\nAmerican Society of Hematology\nMacGRADE Center\nASH Clinical Practice Guidelines on VTE\nVTE prevention in surgical hospitalized patients\nVTE prevention in VTE prevention in medical hospitalized patients\nAcute VTE treatment (DVT and PE)\nOptimal management of anticoagulation therapy\nVTE prevention and treatment in cancer patients\nHeparin-Induced Thrombocytopenia (HIT)\nThrombophilia\nVTE diagnosis\nPediatric VTE\nVTE in the context of pregnancysurgical hospitalized patients\nHow were the ASH guidelines were developed?\nPANEL FORMATION\nEach panel was formed following these key criteria:\nBalance of expertise (including disciplines beyond hematology, and patients)\nAttention to minimization and management of COI\nCLINICAL QUESTIONS\n10 to 20 clinically-relevant questions generated in PICO format (population, intervention, comparison, and outcome)\nEVIDENCE SYNTHESIS\nEvidence analysis for each PICO question x systematic review of effects:\nDesirable and undesirable effects\nResource use\nFeasibility\nAcceptability\nAccessibility\nPatient values and preferences\nPICO QUESTION EXAMPLE\nIn a population of patients with low clinical probability of PTE,  what is the\nbest diagnostic strategy to assess a PTE hypothesis?\nMAKING RECOMMENDATIONS\nRecommendations made by panel members based on evidence for all factors\nASH guidelines are reviewed annually by expert work groups convened by ASH. Resources, such as this slide set, derived from guidel","cbCaifafCOHwCEYJ","https://ap.wps.com/l/cbCaifafCOHwCEYJ","pptx",1305934,52,"English","en",105,"# How were the guidelines developed?\n## Panel formation\n## Clinical questions (PICO)\n## Evidence synthesis\n## Making recommendations\n## Methods (GRADE-ADOLOPMENT)\n# Objectives and diagnostic considerations\n## Prevalence and probability pretest\n## Diagnostic considerations\n# Results of the Latin American guidelines analysis\n## Changes vs original guidance","[{\"question\":\"What method supports the adaptation of evidence-based recommendations in these ASH guidelines?\",\"answer\":\"The slide set emphasizes GRADE-ADOLOPMENT, an explicit method for adoption, adaptation, or development of evidence-based recommendations derived from existing GRADE-focused guidance.\"},{\"question\":\"How are clinical questions structured for evidence review in the guideline development process?\",\"answer\":\"Clinical questions are generated in PICO format, defining the population, intervention, comparison, and outcome for systematic evidence synthesis.\"},{\"question\":\"How does pretest probability relate to VTE diagnosis in the recommendations?\",\"answer\":\"Diagnosis relies on assessing clinical probability before tests, categorizing patients as low/intermediate/high probability or likely/unlikely, which determines expected VTE prevalence and influences the predictive value of diagnostic tests.\"},{\"question\":\"What changes occurred in the Latin American recommendations compared with the original ASH guidelines?\",\"answer\":\"The material reports significant changes to diagnostic recommendations (2/10) and management recommendations (9/18), including both guidance and strength changes.\"}]","Venous Thromboembolism Diagnosis and Management of Special Populations in Latin America - Educational Slide Sets - ASH 2022 | PPTX",1788243646,18,{"code":4,"msg":31,"data":32},"ok",{"site_id":24,"language":23,"slug":33,"title":14,"keywords":34,"description":15,"schema_data":35,"social_meta":91,"head_meta":93,"extra_data":95,"updated_unix":28},"venous-thromboembolism-diagnosis-and-management-of-special-populations-in-latin-america-educational-slide-sets-ash-2022","",{"@graph":36,"@context":90},[37,54,69],{"@type":38,"itemListElement":39},"BreadcrumbList",[40,44,48,51],{"item":41,"name":42,"@type":43,"position":11},"https://docshare.wps.com","Home","ListItem",{"item":45,"name":46,"@type":43,"position":47},"https://docshare.wps.com/template/","Template",2,{"item":49,"name":13,"@type":43,"position":50},"https://docshare.wps.com/template/presentations/",3,{"item":52,"name":14,"@type":43,"position":53},"https://docshare.wps.com/template/venous-thromboembolism-diagnosis-and-management-of-special-populations-in-latin-america-educational-slide-sets-ash-2022/169036/",4,{"url":52,"name":14,"@type":55,"author":56,"headline":14,"publisher":58,"fileFormat":61,"inLanguage":23,"description":15,"dateModified":62,"datePublished":63,"encodingFormat":61,"isAccessibleForFree":64,"interactionStatistic":65},"DigitalDocument",{"name":9,"@type":57},"Person",{"url":41,"name":59,"@type":60},"DocShare","Organization","application/vnd.openxmlformats-officedocument.presentationml.presentation","2026-09-05","2026-09-01",true,{"@type":66,"interactionType":67,"userInteractionCount":11},"InteractionCounter",{"@type":68},"ViewAction",{"@type":70,"mainEntity":71},"FAQPage",[72,78,82,86],{"name":73,"@type":74,"acceptedAnswer":75},"What method supports the adaptation of evidence-based recommendations in these ASH guidelines?","Question",{"text":76,"@type":77},"The slide set emphasizes GRADE-ADOLOPMENT, an explicit method for adoption, adaptation, or development of evidence-based recommendations derived from existing GRADE-focused guidance.","Answer",{"name":79,"@type":74,"acceptedAnswer":80},"How are clinical questions structured for evidence review in the guideline development process?",{"text":81,"@type":77},"Clinical questions are generated in PICO format, defining the population, intervention, comparison, and outcome for systematic evidence synthesis.",{"name":83,"@type":74,"acceptedAnswer":84},"How does pretest probability relate to VTE diagnosis in the recommendations?",{"text":85,"@type":77},"Diagnosis relies on assessing clinical probability before tests, categorizing patients as low/intermediate/high probability or likely/unlikely, which determines expected VTE prevalence and influences the predictive value of diagnostic tests.",{"name":87,"@type":74,"acceptedAnswer":88},"What changes occurred in the Latin American recommendations compared with the original ASH guidelines?",{"text":89,"@type":77},"The material reports significant changes to diagnostic recommendations (2/10) and management recommendations (9/18), including both guidance and strength changes.","https://schema.org",{"og:url":52,"og:type":92,"og:title":14,"og:site_name":59,"og:description":15},"article",{"robots":94,"canonical":52},"index,follow",{"doc_id":7,"site_id":24},{"code":4,"msg":5,"data":97},[98,101,106,111,116,121,126,130,135],{"id":12,"doc_module":11,"doc_module_name":46,"category_name":13,"show_sort_weight":99,"slug":100},90,"presentations",{"id":102,"doc_module":11,"doc_module_name":46,"category_name":103,"show_sort_weight":104,"slug":105},12,"Resumes",80,"resumes",{"id":107,"doc_module":11,"doc_module_name":46,"category_name":108,"show_sort_weight":109,"slug":110},14,"Invoices",70,"invoices",{"id":112,"doc_module":11,"doc_module_name":46,"category_name":113,"show_sort_weight":114,"slug":115},15,"Posters",60,"posters",{"id":117,"doc_module":11,"doc_module_name":46,"category_name":118,"show_sort_weight":119,"slug":120},16,"Social Media",50,"social-media",{"id":122,"doc_module":11,"doc_module_name":46,"category_name":123,"show_sort_weight":124,"slug":125},17,"Forms",40,"forms",{"id":29,"doc_module":11,"doc_module_name":46,"category_name":127,"show_sort_weight":128,"slug":129},"Letters",30,"letters",{"id":131,"doc_module":11,"doc_module_name":46,"category_name":132,"show_sort_weight":133,"slug":134},21,"Paper Templates",5,"papers-templates",{"id":136,"doc_module":11,"doc_module_name":46,"category_name":137,"show_sort_weight":4,"slug":138},158,"General","general-158"]