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Prisma Item Checklist\neAppendix 2. Search Strategy\neAppendix 3. Characteristics of Included Studies\neAppendix 4. CiNEMA Results\neAppendix 5. Network Meta-Analysis Stata Codes\neAppendix 6. Network Meta-Analysis Stata Outputs\neAppendix 7. Results\nContribution Plots\nPredictive Interval Plots\neAppendix 8: Meta-Regression Results\neAppendix 9. References of Included Studies\neAppendix 1. Prisma NMA Item Checklist\nSection/Topic\nItem #\nChecklist Item\nReported on Page #\nTITLE\nTitle\n1\nIdentify the report as a systematic review incorporating a network meta-analysis (or related form of meta-analysis).\n1\nABSTRACT\nStructured summary\n2\nProvide a structured summary including, as applicable:\nBackground: main objectives\nMethods: data sources; study eligibility criteria, participants, and interventions; study appraisal; and synthesis methods, such as network meta-analysis.\nResults: number of studies and participants identified; summary estimates with corresponding confidence/credible intervals; treatment rankings may also be discussed. Authors may choose to summarize pairwise comparisons against a chosen treatment included in their analyses for brevity.\nDiscussion/Conclusions: limitations; conclusions and implications of findings.\nOther: primary source of funding; systematic review registration number with registry name.\n2\nINTRODUCTION\nRationale\n3\nDescribe the rationale for the review in the context of what is already known, including mention of why a network meta-analysis has been conducted.\n6\nObjectives\n4\nProvide an explicit statement of questions being addressed, with reference to participants, interventions, comparisons, outcomes, and study design (PICOS).\n6\nMETHODS\nProtocol and registration\n5\nIndicate whether a review protocol exists and if and where it can be accessed (e.g., Web address); and, if available, provide registration information, including registration number.\n7\nEligibility criteria\n6\nSpecify study characteristics (e.g., PICOS, length of follow-up) and report characteristics (e.g., years considered, language, publication status) used as criteria for eligibility, giving rationale. Clearly describe eligible treatments included in the treatment network, and note whether any have been clustered or merged into the same node (with justification).\n7\nInformation sources\n7\nDescribe all information sources (e.g., databases with dates of coverage, contact with study authors to identify additional studies) in the search and date last searched.\n7\nSearch\n8\nPresent full electronic search strategy for at least one database, including any limits used, such that it could be repeated.\n7\nStudy selection\n9\nState the process for selecting studies (i.e., screening, eligibility, included in systematic review, and, if applicable, included in the meta-analysis).\n7\nData collection process\n10\nDescribe method of data extraction from reports (e.g., piloted forms, independently, in duplicate) and any processes for obtaining and confirming data from investigators.\n9\nData items\n11\nList and define all variables for which data were sought (e.g., PICOS, funding sources) and any assumptions and simplifications made.\n9\nGeometry of the network\nS1\nDescribe methods used to explore the geometry of the treatment network under study and potential biases related to it. This should include how the evidence base has been graphically summarized for presentation, and what characteristics were compiled and used to describe the evidence base to readers.\n6\nRisk of bias within individual studies\n12\nDescribe methods used for assessing risk of bias of individual studies (including specification of whether this was done at the study or outcome level), and how this information is to be used in any data synthesis.\n10\nSummary measures\n13\nState the principal summary measures (e.g., risk ratio, difference in means). Also describe the use of additional summary measures assessed, such as treatment rankings and surface under the cumulative ranki","cbCaiip1v75sUUx3","https://ap.wps.com/l/cbCaiip1v75sUUx3","docx",680516,115,"English","# eAppendix 1. Prisma Item Checklist\n# eAppendix 2. Search Strategy\n# eAppendix 3. Characteristics of Included Studies\n# eAppendix 4. CiNEMA Results\n# eAppendix 5. Network Meta-Analysis Stata Codes\n# eAppendix 6. Network Meta-Analysis Stata Outputs\n# eAppendix 7. Results\n# Contribution Plots\n# Predictive Interval Plots\n# eAppendix 8: Meta-Regression Results\n# eAppendix 9. References of Included Studies\n# Prisma NMA Item Checklist","[{\"question\":\"What does eAppendix 1 provide for reporting the review?\",\"answer\":\"eAppendix 1 provides the PRISMA item checklist for a systematic review incorporating a network meta-analysis, mapping each checklist item to reporting locations.\"},{\"question\":\"What is included in eAppendix 2 for the study search?\",\"answer\":\"eAppendix 2 contains the search strategy, including the full electronic search strategy details so the search can be repeated.\"},{\"question\":\"Which materials support the network meta-analysis computations and figures?\",\"answer\":\"eAppendix 5 and eAppendix 6 provide Stata codes and outputs, while eAppendix 7 includes results plus contribution plots and predictive interval plots. Additional visuals include meta-regression results in eAppendix 8.\"}]","Supplemental Materials - Prisma Item Checklist and Network Meta-Analysis Appendices | DOCX"]