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Applicants must provide investigator and project details, identify academic or industry partnership requirements, and specify whether biospecimens will be requested from MJFF for designated cohorts. The template guides respondents to select the primary disease aspect targeted by the therapeutic, either disease symptoms or pathological molecular changes, and to compile the narrative within defined formatting constraints.",{"@graph":63,"@context":118},[64,80,101],{"@type":65,"itemListElement":66},"BreadcrumbList",[67,71,74,77],{"item":68,"name":69,"@type":70,"position":9},"https://docshare.wps.com","Home","ListItem",{"item":72,"name":10,"@type":70,"position":73},"https://docshare.wps.com/template/",2,{"item":75,"name":36,"@type":70,"position":76},"https://docshare.wps.com/template/forms/",3,{"item":78,"name":59,"@type":70,"position":79},"https://docshare.wps.com/template/pre-clinical-track-parkinsons-disease-therapeutics-pipeline-program-pre-proposal-template/163610/",4,{"url":78,"name":59,"@type":81,"image":82,"author":87,"headline":59,"publisher":90,"fileFormat":93,"inLanguage":57,"description":61,"dateModified":94,"datePublished":95,"encodingFormat":93,"isAccessibleForFree":96,"interactionStatistic":97},"DigitalDocument",{"url":83,"@type":84,"width":85,"height":86},"https://docshare.wps.com/thumbnails/pre-clinical-track-parkinsons-disease-therapeutics-pipeline-program-pre-proposal-template/163610.png","ImageObject",442,249,{"name":88,"@type":89},"Asher","Person",{"url":68,"name":91,"@type":92},"DocShare","Organization","application/vnd.openxmlformats-officedocument.wordprocessingml.document","2026-09-22","2026-08-31",true,{"@type":98,"interactionType":99,"userInteractionCount":79},"InteractionCounter",{"@type":100},"ViewAction",{"@type":102,"mainEntity":103},"FAQPage",[104,110,114],{"name":105,"@type":106,"acceptedAnswer":107},"What information must be provided in the pre-proposal?","Question",{"text":108,"@type":109},"The form requires Principal Investigator, Institution/Company, Project Title, and an Academic or Industry Partner, and it includes checkbox responses to guide review assignment.","Answer",{"name":111,"@type":106,"acceptedAnswer":112},"Are academic applicants allowed without an industry partner?",{"text":113,"@type":109},"No. All academic applicants must have an industry partner.",{"name":115,"@type":106,"acceptedAnswer":116},"How should applicants choose the primary disease aspect targeted by the therapeutic?",{"text":117,"@type":109},"Select either disease symptom(s) addressed (motor or non-motor) or pathological underlying molecular changes addressed, choosing the most direct main target even if outcomes include broader symptom improvement.","https://schema.org",{"og:url":78,"og:type":120,"og:title":59,"og:site_name":91,"og:description":61},"article",{"robots":122,"canonical":78},"index,follow",{"doc_id":124,"site_id":56},163610,1788145755,{"code":4,"msg":5,"data":127},{"doc_id":124,"user_id":128,"nickname":88,"user_avatar":129,"doc_module":9,"category_id":35,"category_name":36,"doc_title":59,"doc_description":61,"doc_content":130,"file_id":131,"file_url":132,"file_type":133,"file_size":134,"view_count":79,"is_deleted":4,"is_public":9,"is_downloadable":9,"audit_status":9,"page_count":76,"language":135,"language_code":57,"site_id":56,"html_lang":57,"table_of_contents":136,"faqs":137,"seo_title":138,"seo_description":61,"update_tm":125,"read_time":9},687197207639,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","PARKINSON’S DISEASE THERAPEUTICS PIPELINE PROGRAM\nRequest for Applications\nPre-Clinical Track\npre-proposal\nPlease answer the following checkbox questions and use the template below to create your pre-proposal and upload a single PDF copy with your online submission.\nPrincipal Investigator:\nInstitution/Company:\nProject Title:\nAcademic or Industry Partner:\n(all academic applicants must have an industry partner)\n\u0003☐\u0004 I plan to request biospecimens from MJFF for use in this project. If yes, please indicate which cohort in the template below and complete the provided Biosample Request form in its entirety and upload a PDF copy with your online submission.\nPlease check one box indicating the primary aspect of the disease that the proposed therapeutic is intended to directly and specifically address, so that we can assign your pre-proposal to the correct scientific review tract. Please choose either a Disease symptom(s) or a Pathological underlying molecular changes category. Select a pathological underlying molecular change if that is the main, most direct target of the proposed therapeutic approach, even if the final desired outcome of the proposed therapy may well be to reduce or improve any of the motor and/or non-motor symptoms of the disease.\nDisease symptoms addressed by my therapeutic intervention:\n☐ Motor symptoms of Parkinson’s disease (PD) or as result of standard of care (gait disorder, falling, tremor, etc.)\n☐ Non-motor disease symptoms (cognitive changes, apathy, depression, etc.)\nOr,\nPathological underlying molecular changes addressed by my therapeutic intervention:\n☐ Alpha-synuclein\n☐ LRRK2/GBA1/Lysosomal-Endolysosomal dysfunction\n☐ PARKIN/PINK1/Mitochondria-mitophagy dysfunction\n☐ NLRP3/Inflammation/Neuroinflammation/Immune activation\n☐ Other(s)\nTEMPLATE\nText should be no smaller than 11-pt font and not exceed 2 pages. Please carefully read the instructional text within each box and address each point in your response. Replace the instructional text with your responses in the second column of the table, maintaining the headings in the first column. We encourage the use of bullet points, when appropriate, as well as the submission of schematics, images and/or graphs accompanying any unpublished preliminary data. Optional literature references as well as schematics, images and/or graphs are excluded from the 2-page limit.","cbCaieFyiJo3uFDh","https://ap.wps.com/l/cbCaieFyiJo3uFDh","docx",108410,"English","# Request for Applications\n## Pre-Proposal Submission Requirements\n## Applicant and Project Information\n## Biospecimen Request Checkbox\n## Therapeutic Target Selection (Symptoms or Molecular Changes)\n## Template and Formatting Rules","[{\"question\":\"What information must be provided in the pre-proposal?\",\"answer\":\"The form requires Principal Investigator, Institution/Company, Project Title, and an Academic or Industry Partner, and it includes checkbox responses to guide review assignment.\"},{\"question\":\"Are academic applicants allowed without an industry partner?\",\"answer\":\"No. All academic applicants must have an industry partner.\"},{\"question\":\"How should applicants choose the primary disease aspect targeted by the therapeutic?\",\"answer\":\"Select either disease symptom(s) addressed (motor or non-motor) or pathological underlying molecular changes addressed, choosing the most direct main target even if outcomes include broader symptom improvement.\"}]","Pre-Clinical Track - Parkinson’s Disease Therapeutics Pipeline Program Pre-Proposal Template | DOCX"]