[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-1-en-105":3,"doc-seo-564911-105":53,"doc-detail-564911-en":127},{"code":4,"msg":5,"data":6},0,"success",[7,14,19,24,29,34,39,44,49],{"id":8,"doc_module":9,"doc_module_name":10,"category_name":11,"show_sort_weight":12,"slug":13},11,1,"Template","Presentations",90,"presentations",{"id":15,"doc_module":9,"doc_module_name":10,"category_name":16,"show_sort_weight":17,"slug":18},12,"Resumes",80,"resumes",{"id":20,"doc_module":9,"doc_module_name":10,"category_name":21,"show_sort_weight":22,"slug":23},14,"Invoices",70,"invoices",{"id":25,"doc_module":9,"doc_module_name":10,"category_name":26,"show_sort_weight":27,"slug":28},15,"Posters",60,"posters",{"id":30,"doc_module":9,"doc_module_name":10,"category_name":31,"show_sort_weight":32,"slug":33},16,"Social Media",50,"social-media",{"id":35,"doc_module":9,"doc_module_name":10,"category_name":36,"show_sort_weight":37,"slug":38},17,"Forms",40,"forms",{"id":40,"doc_module":9,"doc_module_name":10,"category_name":41,"show_sort_weight":42,"slug":43},18,"Letters",30,"letters",{"id":45,"doc_module":9,"doc_module_name":10,"category_name":46,"show_sort_weight":47,"slug":48},21,"Paper Templates",5,"papers-templates",{"id":50,"doc_module":9,"doc_module_name":10,"category_name":51,"show_sort_weight":4,"slug":52},158,"General","general-158",{"code":4,"msg":54,"data":55},"ok",{"site_id":56,"language":57,"slug":58,"title":59,"keywords":60,"description":61,"schema_data":62,"social_meta":120,"head_meta":122,"extra_data":124,"updated_unix":126},105,"en","pka-and-pi-values-of-amino-acids-reference-table","pKa and pI values of amino acids - Reference Table","","This document provides a comprehensive scientific reference table detailing the pKa values for the alpha-carboxyl group, the alpha-amino group, and the side chain, along with the calculated isoelectric point (pI) for all twenty standard proteinogenic amino acids. The data is presented in a clear, organized format, including both three-letter and one-letter codes for each residue. This resource is intended for researchers, students, and laboratory professionals engaged in peptide synthesis, biochemistry, and protein chemistry, offering essential thermodynamic constants for experimental design and data analysis in molecular biology and analytical applications.",{"@graph":63,"@context":119},[64,80,102],{"@type":65,"itemListElement":66},"BreadcrumbList",[67,71,74,77],{"item":68,"name":69,"@type":70,"position":9},"https://docshare.wps.com","Home","ListItem",{"item":72,"name":10,"@type":70,"position":73},"https://docshare.wps.com/template/",2,{"item":75,"name":51,"@type":70,"position":76},"https://docshare.wps.com/template/general/",3,{"item":78,"name":59,"@type":70,"position":79},"https://docshare.wps.com/template/pka-and-pi-values-of-amino-acids-reference-table/564911/",4,{"url":78,"name":59,"@type":81,"image":82,"author":87,"headline":59,"publisher":90,"fileFormat":93,"inLanguage":57,"description":61,"dateModified":94,"datePublished":95,"encodingFormat":93,"isAccessibleForFree":96,"interactionStatistic":97},"DigitalDocument",{"url":83,"@type":84,"width":85,"height":86},"https://docshare.wps.com/thumbnails/pka-and-pi-values-of-amino-acids-reference-table/564911.png","ImageObject",442,249,{"name":88,"@type":89},"Himbo","Person",{"url":68,"name":91,"@type":92},"DocShare","Organization","application/pdf","2026-10-28","2026-10-12",true,{"@type":98,"interactionType":99,"userInteractionCount":101},"InteractionCounter",{"@type":100},"ViewAction",7,{"@type":103,"mainEntity":104},"FAQPage",[105,111,115],{"name":106,"@type":107,"acceptedAnswer":108},"What is the isoelectric point of Arginine?","Question",{"text":109,"@type":110},"The isoelectric point (pI) of Arginine is 10.76.","Answer",{"name":112,"@type":107,"acceptedAnswer":113},"Which amino acids have a side chain pKa value listed?",{"text":114,"@type":110},"Amino acids with listed side chain pKa values include Arginine, Aspartic acid, Cysteine, Glutamic acid, Histidine, Lysine, and Tyrosine.",{"name":116,"@type":107,"acceptedAnswer":117},"What is the pKa of the alpha-carboxyl group for Glycine?",{"text":118,"@type":110},"The pKa of the alpha-carboxyl group for Glycine is 2.34.","https://schema.org",{"og:url":78,"og:type":121,"og:title":59,"og:site_name":91,"og:description":61},"article",{"robots":123,"canonical":78},"index,follow",{"doc_id":125,"site_id":56},564911,1792087325,{"code":4,"msg":5,"data":128},{"doc_id":125,"user_id":129,"nickname":88,"user_avatar":130,"doc_module":9,"category_id":50,"category_name":51,"doc_title":59,"doc_description":61,"doc_content":131,"file_id":132,"file_url":133,"file_type":134,"file_size":135,"view_count":101,"is_deleted":4,"is_public":9,"is_downloadable":9,"audit_status":9,"page_count":9,"language":136,"language_code":57,"site_id":56,"html_lang":57,"table_of_contents":137,"faqs":138,"seo_title":139,"seo_description":61,"update_tm":140,"read_time":4},687197100911,"https://ap-avatar.wpscdn.com/avatar/a000239b6f1da00475?x-image-process=image/resize,m_fixed,w_180,h_180&k=1785132997149421697","| pKa and pI values of amino acids |  |  |  |  |  |  |\n| --- | --- | --- | --- | --- | --- | --- |\n| Amino acid | 3-letter code | 1-letter code | pKa\u003Cbr>Cα-COOH | pKa Cα-NH3+ | pKaside chain | Isoelectric point (pI) |\n| Alanine | Ala | A | 2.34 | 9.69 | - | 6.02 |\n| Arginine | Arg | R | 2.17 | 9.04 | 12.48 | 10.76 |\n| Asparagine | Asn | N | 2.02 | 8.80 | - | 5.41 |\n| Aspartic acid | Asp | D | 2.09 | 9.82 | 3.86 | 2.98 |\n| Cysteine | Cys | C | 1.71 | 10.78 | 8.33 | 5.02 |\n| Glutamic acid | Glu | E | 2.19 | 9.67 | 4.25 | 3.22 |\n| Glutamine | Gln | Q | 2.17 | 9.13 | - | 5.65 |\n| Glycine | Gly | G | 2.34 | 9.60 | - | 5.97 |\n| Histidine | His | H | 1.82 | 9.17 | 6.00 | 7.59 |\n| Isoleucine | Ile | I | 2.36 | 9.60 | - | 5.98 |\n| Leucine | Leu | L | 2.36 | 9.60 | - | 5.98 |\n| Lysine | Lys | K | 2.18 | 8.95 | 10.79 | 9.87 |\n| Methionine | Met | M | 2.28 | 9.21 | - | 5.75 |\n| Phenylalanine | Phe | F | 1.83 | 9.13 | - | 5.48 |\n| Proline | Pro | P | 1.99 | 10.60 | - | 6.30 |\n| Serine | Ser | S | 2.21 | 9.15 | - | 5.68 |\n| Threonine | Thr | T | 2.09 | 9.10 | - | 5.60 |\n| Tryptophan | Trp | W | 2.43 | 9.44 | - | 5.94 |\n| Tyrosine | Tyr | Y | 2.20 | 9.11 | 10.07 | 5.66 |\n| Valine | Val | V | 2.32 | 9.62 | - | 5.97 |\n\n[www.peptideweb.com](www.peptideweb.com)  \nCustom peptide synthesis | Equipment, glassware and reagents for peptide synthesis","cbCaiiNNdPSGuH8D","https://ap.wps.com/l/cbCaiiNNdPSGuH8D","pdf",222229,"English","# Amino Acid Properties Table\n## pKa and pI Data","[{\"question\":\"What is the isoelectric point of Arginine?\",\"answer\":\"The isoelectric point (pI) of Arginine is 10.76.\"},{\"question\":\"Which amino acids have a side chain pKa value listed?\",\"answer\":\"Amino acids with listed side chain pKa values include Arginine, Aspartic acid, Cysteine, Glutamic acid, Histidine, Lysine, and Tyrosine.\"},{\"question\":\"What is the pKa of the alpha-carboxyl group for Glycine?\",\"answer\":\"The pKa of the alpha-carboxyl group for Glycine is 2.34.\"}]","pKa and pI values of amino acids - Reference Table | PDF",1791845022]