[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-1-en-105":3,"doc-seo-563617-105":53,"doc-detail-563617-en":127},{"code":4,"msg":5,"data":6},0,"success",[7,14,19,24,29,34,39,44,49],{"id":8,"doc_module":9,"doc_module_name":10,"category_name":11,"show_sort_weight":12,"slug":13},11,1,"Template","Presentations",90,"presentations",{"id":15,"doc_module":9,"doc_module_name":10,"category_name":16,"show_sort_weight":17,"slug":18},12,"Resumes",80,"resumes",{"id":20,"doc_module":9,"doc_module_name":10,"category_name":21,"show_sort_weight":22,"slug":23},14,"Invoices",70,"invoices",{"id":25,"doc_module":9,"doc_module_name":10,"category_name":26,"show_sort_weight":27,"slug":28},15,"Posters",60,"posters",{"id":30,"doc_module":9,"doc_module_name":10,"category_name":31,"show_sort_weight":32,"slug":33},16,"Social Media",50,"social-media",{"id":35,"doc_module":9,"doc_module_name":10,"category_name":36,"show_sort_weight":37,"slug":38},17,"Forms",40,"forms",{"id":40,"doc_module":9,"doc_module_name":10,"category_name":41,"show_sort_weight":42,"slug":43},18,"Letters",30,"letters",{"id":45,"doc_module":9,"doc_module_name":10,"category_name":46,"show_sort_weight":47,"slug":48},21,"Paper Templates",5,"papers-templates",{"id":50,"doc_module":9,"doc_module_name":10,"category_name":51,"show_sort_weight":4,"slug":52},158,"General","general-158",{"code":4,"msg":54,"data":55},"ok",{"site_id":56,"language":57,"slug":58,"title":59,"keywords":60,"description":61,"schema_data":62,"social_meta":120,"head_meta":122,"extra_data":124,"updated_unix":126},105,"en","mots-c-dosage-and-reconstitution-guidelines","MOTS-c - Dosage and Reconstitution Guidelines","","This document provides comprehensive clinical guidelines for the administration and reconstitution of MOTS-c, a mitochondrial-derived peptide. It outlines standardized dosing protocols, including starting, ramp-up, and maintenance phases, alongside specific instructions for reconstitution using bacteriostatic water to achieve the required concentration. The guide emphasizes the importance of physician-led decision-making for individual patient requirements and provides specific considerations for patients with type 2 diabetes. Additionally, the document details cycle-specific requirements based on total vial usage, ensuring that healthcare providers have clear, actionable data for safe clinical application. The provided information aims to assist in managing mitochondrial function through accurate, medically informed administration practices.",{"@graph":63,"@context":119},[64,80,102],{"@type":65,"itemListElement":66},"BreadcrumbList",[67,71,74,77],{"item":68,"name":69,"@type":70,"position":9},"https://docshare.wps.com","Home","ListItem",{"item":72,"name":10,"@type":70,"position":73},"https://docshare.wps.com/template/",2,{"item":75,"name":51,"@type":70,"position":76},"https://docshare.wps.com/template/general/",3,{"item":78,"name":59,"@type":70,"position":79},"https://docshare.wps.com/template/mots-c-dosage-and-reconstitution-guidelines/563617/",4,{"url":78,"name":59,"@type":81,"image":82,"author":87,"headline":59,"publisher":90,"fileFormat":93,"inLanguage":57,"description":61,"dateModified":94,"datePublished":95,"encodingFormat":93,"isAccessibleForFree":96,"interactionStatistic":97},"DigitalDocument",{"url":83,"@type":84,"width":85,"height":86},"https://docshare.wps.com/thumbnails/mots-c-dosage-and-reconstitution-guidelines/563617.png","ImageObject",442,249,{"name":88,"@type":89},"Riley West","Person",{"url":68,"name":91,"@type":92},"DocShare","Organization","application/pdf","2026-10-25","2026-10-12",true,{"@type":98,"interactionType":99,"userInteractionCount":101},"InteractionCounter",{"@type":100},"ViewAction",8,{"@type":103,"mainEntity":104},"FAQPage",[105,111,115],{"name":106,"@type":107,"acceptedAnswer":108},"How is the MOTS-c 10mg vial reconstituted?","Question",{"text":109,"@type":110},"Add 1mL of bacteriostatic water to the 10mg vial to achieve a concentration of 0.1mg/unit.","Answer",{"name":112,"@type":107,"acceptedAnswer":113},"What is the recommended injection frequency for a standard cycle?",{"text":114,"@type":110},"The suggested dose is administered via subcutaneous injection once every 5 days for a duration of 20 days.",{"name":116,"@type":107,"acceptedAnswer":117},"Are there specific dosage adjustments for patients with type 2 diabetes?",{"text":118,"@type":110},"Yes, for type 2 diabetic patients, a lower dose of 1mg administered every other day (EOD) is suggested to help lower blood sugar levels.","https://schema.org",{"og:url":78,"og:type":121,"og:title":59,"og:site_name":91,"og:description":61},"article",{"robots":123,"canonical":78},"index,follow",{"doc_id":125,"site_id":56},563617,1792086998,{"code":4,"msg":5,"data":128},{"doc_id":125,"user_id":129,"nickname":88,"user_avatar":130,"doc_module":9,"category_id":50,"category_name":51,"doc_title":59,"doc_description":61,"doc_content":131,"file_id":132,"file_url":133,"file_type":134,"file_size":135,"view_count":101,"is_deleted":4,"is_public":9,"is_downloadable":9,"audit_status":9,"page_count":9,"language":136,"language_code":57,"site_id":56,"html_lang":57,"table_of_contents":137,"faqs":138,"seo_title":139,"seo_description":61,"update_tm":140,"read_time":4},1099523885074,"https://ap-avatar.wpscdn.com/davatar_9964176cb1d06d4a9deccf72a44ae3dc","The chart below shows various dosing options coupled with the amount (in mg) and frequency for each dose. Dosing should be determined by the physician on an individual patient basis.  \nReconstitution Instructions for our 10mg vial  \nAdd 1mL bacteriostatic water → 0.1mg/unit concentration  \n\n| Dose | Amount | Units |\n| --- | --- | --- |\n| Starting | 5 mg | 50 units |\n| Ramp-Up | 75 mg | 75 units |\n| Maintenance | 100 mg | 100 units |\n\nDISCLAIMER: This dosing chart serves to provide general dosing guidelines reflecting generally accepted practices at the time of publication. It is not designed to substitute for the individual advice and decision-making provided by a licensed physician. Individual patient factors will influence optimal dosing and should be considered.","cbCaibCWlnomoJBy","https://ap.wps.com/l/cbCaibCWlnomoJBy","pdf",144206,"English","# Reconstitution Instructions\n## Dosing Options and Frequency\n## Clinical Notes and Considerations","[{\"question\":\"How is the MOTS-c 10mg vial reconstituted?\",\"answer\":\"Add 1mL of bacteriostatic water to the 10mg vial to achieve a concentration of 0.1mg/unit.\"},{\"question\":\"What is the recommended injection frequency for a standard cycle?\",\"answer\":\"The suggested dose is administered via subcutaneous injection once every 5 days for a duration of 20 days.\"},{\"question\":\"Are there specific dosage adjustments for patients with type 2 diabetes?\",\"answer\":\"Yes, for type 2 diabetic patients, a lower dose of 1mg administered every other day (EOD) is suggested to help lower blood sugar levels.\"}]","MOTS-c - Dosage and Reconstitution Guidelines | PDF",1791836858]