[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-1-en-105":3,"doc-seo-176529-105":53,"doc-detail-176529-en":126},{"code":4,"msg":5,"data":6},0,"success",[7,14,19,24,29,34,39,44,49],{"id":8,"doc_module":9,"doc_module_name":10,"category_name":11,"show_sort_weight":12,"slug":13},11,1,"Template","Presentations",90,"presentations",{"id":15,"doc_module":9,"doc_module_name":10,"category_name":16,"show_sort_weight":17,"slug":18},12,"Resumes",80,"resumes",{"id":20,"doc_module":9,"doc_module_name":10,"category_name":21,"show_sort_weight":22,"slug":23},14,"Invoices",70,"invoices",{"id":25,"doc_module":9,"doc_module_name":10,"category_name":26,"show_sort_weight":27,"slug":28},15,"Posters",60,"posters",{"id":30,"doc_module":9,"doc_module_name":10,"category_name":31,"show_sort_weight":32,"slug":33},16,"Social Media",50,"social-media",{"id":35,"doc_module":9,"doc_module_name":10,"category_name":36,"show_sort_weight":37,"slug":38},17,"Forms",40,"forms",{"id":40,"doc_module":9,"doc_module_name":10,"category_name":41,"show_sort_weight":42,"slug":43},18,"Letters",30,"letters",{"id":45,"doc_module":9,"doc_module_name":10,"category_name":46,"show_sort_weight":47,"slug":48},21,"Paper Templates",5,"papers-templates",{"id":50,"doc_module":9,"doc_module_name":10,"category_name":51,"show_sort_weight":4,"slug":52},158,"General","general-158",{"code":4,"msg":54,"data":55},"ok",{"site_id":56,"language":57,"slug":58,"title":59,"keywords":60,"description":61,"schema_data":62,"social_meta":119,"head_meta":121,"extra_data":123,"updated_unix":125},105,"en","molecularly-imprinted-polymer-for-selective-adsorption-of-diclofenac-from-contaminated-water-chemengj-2019","Molecularly imprinted polymer for selective adsorption of diclofenac from contaminated water - chemengj 2019","","Pharmaceutical contamination in aquatic environments, particularly non-steroidal anti-inflammatory drugs (NSAIDs), poses a worldwide risk because conventional wastewater treatment processes do not remove these “emerging contaminants” efficiently. The study proposes molecularly imprinted polymers (MIPs) for selective adsorption and removal from water, focusing on a diclofenac-selective MIP prepared by simple bulk polymerization. Characterization confirms imprinting-enabled, highly selective recognition toward diclofenac in aqueous solution, with adsorption compared to a non-imprinted polymer and evaluated against other drugs. Regeneration supports reusability, and the low-cost, water-compatible synthesis supports large-scale treatment potential.",{"@graph":63,"@context":118},[64,80,101],{"@type":65,"itemListElement":66},"BreadcrumbList",[67,71,74,77],{"item":68,"name":69,"@type":70,"position":9},"https://docshare.wps.com","Home","ListItem",{"item":72,"name":10,"@type":70,"position":73},"https://docshare.wps.com/template/",2,{"item":75,"name":51,"@type":70,"position":76},"https://docshare.wps.com/template/general/",3,{"item":78,"name":59,"@type":70,"position":79},"https://docshare.wps.com/template/molecularly-imprinted-polymer-for-selective-adsorption-of-diclofenac-from-contaminated-water-chemengj-2019/176529/",4,{"url":78,"name":59,"@type":81,"image":82,"author":87,"headline":59,"publisher":90,"fileFormat":93,"inLanguage":57,"description":61,"dateModified":94,"datePublished":95,"encodingFormat":93,"isAccessibleForFree":96,"interactionStatistic":97},"DigitalDocument",{"url":83,"@type":84,"width":85,"height":86},"https://docshare.wps.com/thumbnails/molecularly-imprinted-polymer-for-selective-adsorption-of-diclofenac-from-contaminated-water-chemengj-2019/176529.png","ImageObject",442,249,{"name":88,"@type":89},"Nguyễn Văn Học","Person",{"url":68,"name":91,"@type":92},"DocShare","Organization","application/vnd.openxmlformats-officedocument.wordprocessingml.document","2026-09-29","2026-09-02",true,{"@type":98,"interactionType":99,"userInteractionCount":79},"InteractionCounter",{"@type":100},"ViewAction",{"@type":102,"mainEntity":103},"FAQPage",[104,110,114],{"name":105,"@type":106,"acceptedAnswer":107},"Why is diclofenac considered an important emerging contaminant in water?","Question",{"text":108,"@type":109},"Diclofenac is widely detected in surface water, groundwater, and drinking water, and exposure—even at low concentrations—can cause chronic toxicological effects and form potentially more harmful metabolites.","Answer",{"name":111,"@type":106,"acceptedAnswer":112},"How are diclofenac-selective molecularly imprinted polymers (MIPs) prepared and evaluated?",{"text":113,"@type":109},"The study prepares a diclofenac-selective MIP via simple bulk polymerization, characterizes the polymers, and evaluates binding by adsorbing diclofenac in aqueous solution compared with a non-imprinted polymer.",{"name":115,"@type":106,"acceptedAnswer":116},"What evidence supports selective adsorption and the role of imprinting?",{"text":117,"@type":109},"The MIP shows extreme selectivity toward the template molecule diclofenac, and adsorption abilities are tested against other drugs such as acetylsalicylic acid and trimethoprim to demonstrate imprinting-driven recognition.","https://schema.org",{"og:url":78,"og:type":120,"og:title":59,"og:site_name":91,"og:description":61},"article",{"robots":122,"canonical":78},"index,follow",{"doc_id":124,"site_id":56},176529,1788324733,{"code":4,"msg":5,"data":127},{"doc_id":124,"user_id":128,"nickname":88,"user_avatar":129,"doc_module":9,"category_id":50,"category_name":51,"doc_title":59,"doc_description":61,"doc_content":130,"file_id":131,"file_url":132,"file_type":133,"file_size":134,"view_count":79,"is_deleted":4,"is_public":9,"is_downloadable":9,"audit_status":9,"page_count":135,"language":136,"language_code":57,"site_id":56,"html_lang":57,"table_of_contents":137,"faqs":138,"seo_title":139,"seo_description":61,"update_tm":125,"read_time":140},1374402739827,"https://ap-avatar.wpscdn.com/avatar/14000c97e7351f1a627?x-image-process=image/resize,m_fixed,w_180,h_180&k=1787885694763230660","Molecularly imprinted polymer for selective adsorption of diclofenac from contaminated water\nMaria Cantarella a*, Sabrina C. Carroccio a,b, Sandro Dattilo b, Roberto Avolio c, Rachele Castaldo c, Concetto Puglisi b, Vittorio Privitera a\na CNR-IMM, Via S. Sofia 64, 95123 Catania, Italy\nb CNR-IPCB, Via Paolo Gaifami 18, 95126 Catania, Italy\nc CNR-IPCB, Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy\n*Corresponding author\nE-mail address: \u0013 HYPERLINK \"mailto:maria.cantarella@ct.infn.it\" \u0014maria.cantarella@ct.infn.it\u0015 (M. Cantarella)\nAbstract\nThe presence of pharmaceuticals, such as non-steroidal anti-inflammatory drugs (NSAIDs) in the aquatic environment represents a worldwide threat. NSAIDs are considered “emerging contaminants” of water since the traditional methods are not designed to efficiently remove them. Aiming to overcome the limits of the conventional wastewater treatment plants, we propose molecularly imprinted polymers (MIPs) as valid tools for selective adsorption and removal of these drugs from water. In particular, in this work, we have prepared diclofenac-selective MIP by a simple bulk polymerization process. After the characterization of the synthetized polymers, the binding abilities were evaluated in detail through the adsorption of diclofenac in aqueous solution and compared with the abilities of a corresponding non-imprinted polymer used as a reference. Thanks to the imprinting effect, the prepared MIP adsorbs with extreme selectivity its template molecule, i.e. the diclofenac. This effect was evaluated by testing the adsorption abilities towards different drugs, such as acetylsalicylic acid and trimethoprim. In addition, MIP reusability was demonstrated after a simple regeneration step. The strength of this work is due to the low cost synthesis of MIP and to its optimal performance of molecular recognition in water, differentially from many of the traditional MIPs, usually used with organic solvent. Such peculiarities make the material potentially applicable for water treatment on a large scale.\nKEYWORDS: molecularly imprinted polymers; water treatment; emerging contaminants, diclofenac; selective adsorption; non-steroidal anti-inflammatory drugs.\n1. Introduction\nNowadays, the contamination of water resources due to new industrial and human activities is becoming more and more dramatic, posing a serious threat for human health. A lot of organic substances, such as human pharmaceuticals, veterinary medicines, personal care products, have been recently detected in surface water, groundwater, and also drinking water [1]. These new emerging pollutants are considered very dangerous, even if in traces, because they could provoke severe ecological side effects. For this reason, water pollution by these compounds is becoming a subject of global concern attracting significant interest among the major international organizations such as World Health Organization, United States Geological Survey, United States Environmental Protection Agency and the European Commission [2].\nAmong the several emerging pollutants, non-steroidal anti-inflammatory drugs (NSAIDs), in particular diclofenac, are the most common compounds detected in environmental compartments due to their large consumption throughout the world. It has been demonstrated that extended exposure even at low concentration to this drug may lead to chronic toxicological effects, and some studies suspected that some diclofenac metabolites might be potentially more toxic than the parent compound. In addition, diclofenac can interact with other inorganic or organic contaminants of wastewater matrix producing more dangerous compounds [3]. Diclofenac and the other NSAIDs enter the environment via anthropogenic activities and have been detected in surface water, groundwater and even drinking water. Their main sources are the effluents from the traditional municipal wastewater treatment plants which are unable of treating such substances at very low concentrations (typicall","cbCaisdFlYcJ0ySQ","https://ap.wps.com/l/cbCaisdFlYcJ0ySQ","docx",994581,27,"English","# Abstract\n# Introduction\n## Emerging contaminants in water\n## Focus on NSAIDs and diclofenac\n## Molecularly imprinted polymers as a selective adsorption approach","[{\"question\":\"Why is diclofenac considered an important emerging contaminant in water?\",\"answer\":\"Diclofenac is widely detected in surface water, groundwater, and drinking water, and exposure—even at low concentrations—can cause chronic toxicological effects and form potentially more harmful metabolites.\"},{\"question\":\"How are diclofenac-selective molecularly imprinted polymers (MIPs) prepared and evaluated?\",\"answer\":\"The study prepares a diclofenac-selective MIP via simple bulk polymerization, characterizes the polymers, and evaluates binding by adsorbing diclofenac in aqueous solution compared with a non-imprinted polymer.\"},{\"question\":\"What evidence supports selective adsorption and the role of imprinting?\",\"answer\":\"The MIP shows extreme selectivity toward the template molecule diclofenac, and adsorption abilities are tested against other drugs such as acetylsalicylic acid and trimethoprim to demonstrate imprinting-driven recognition.\"}]","Molecularly imprinted polymer for selective adsorption of diclofenac from contaminated water - chemengj 2019 | DOCX",9]