[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-1-en-105":3,"doc-seo-219162-105":53,"doc-detail-219162-en":126},{"code":4,"msg":5,"data":6},0,"success",[7,14,19,24,29,34,39,44,49],{"id":8,"doc_module":9,"doc_module_name":10,"category_name":11,"show_sort_weight":12,"slug":13},11,1,"Template","Presentations",90,"presentations",{"id":15,"doc_module":9,"doc_module_name":10,"category_name":16,"show_sort_weight":17,"slug":18},12,"Resumes",80,"resumes",{"id":20,"doc_module":9,"doc_module_name":10,"category_name":21,"show_sort_weight":22,"slug":23},14,"Invoices",70,"invoices",{"id":25,"doc_module":9,"doc_module_name":10,"category_name":26,"show_sort_weight":27,"slug":28},15,"Posters",60,"posters",{"id":30,"doc_module":9,"doc_module_name":10,"category_name":31,"show_sort_weight":32,"slug":33},16,"Social Media",50,"social-media",{"id":35,"doc_module":9,"doc_module_name":10,"category_name":36,"show_sort_weight":37,"slug":38},17,"Forms",40,"forms",{"id":40,"doc_module":9,"doc_module_name":10,"category_name":41,"show_sort_weight":42,"slug":43},18,"Letters",30,"letters",{"id":45,"doc_module":9,"doc_module_name":10,"category_name":46,"show_sort_weight":47,"slug":48},21,"Paper Templates",5,"papers-templates",{"id":50,"doc_module":9,"doc_module_name":10,"category_name":51,"show_sort_weight":4,"slug":52},158,"General","general-158",{"code":4,"msg":54,"data":55},"ok",{"site_id":56,"language":57,"slug":58,"title":59,"keywords":60,"description":61,"schema_data":62,"social_meta":119,"head_meta":121,"extra_data":123,"updated_unix":125},105,"en","israel-aging-protocols-with-hbot-full-study-protocol-included","Israel Aging Protocols with HBOT - Full Study - Protocol Included","","Hyperbaric oxygen therapy (HBOT) protocols were evaluated in an aging, non-pathological adult population, focusing on whether intermittent hyperoxic exposure influences telomere length and cellular senescence. The protocol delivered 60 daily sessions over a three-month timeframe, using 100% oxygen at 2 ATA with defined compression/decompression times and air breaks to reduce oxygen toxicity risk. Blood sampling occurred at baseline, during the 30th and 60th sessions, and 1–2 weeks after the last session. Results showed telomere length increases across multiple lymphocyte subsets and a reduction in senescent T-cell measures post-HBOT.",{"@graph":63,"@context":118},[64,80,101],{"@type":65,"itemListElement":66},"BreadcrumbList",[67,71,74,77],{"item":68,"name":69,"@type":70,"position":9},"https://docshare.wps.com","Home","ListItem",{"item":72,"name":10,"@type":70,"position":73},"https://docshare.wps.com/template/",2,{"item":75,"name":46,"@type":70,"position":76},"https://docshare.wps.com/template/paper-templates/",3,{"item":78,"name":59,"@type":70,"position":79},"https://docshare.wps.com/template/israel-aging-protocols-with-hbot-full-study-protocol-included/219162/",4,{"url":78,"name":59,"@type":81,"image":82,"author":87,"headline":59,"publisher":90,"fileFormat":93,"inLanguage":57,"description":61,"dateModified":94,"datePublished":95,"encodingFormat":93,"isAccessibleForFree":96,"interactionStatistic":97},"DigitalDocument",{"url":83,"@type":84,"width":85,"height":86},"https://docshare.wps.com/thumbnails/israel-aging-protocols-with-hbot-full-study-protocol-included/219162.png","ImageObject",442,249,{"name":88,"@type":89},"Oliver","Person",{"url":68,"name":91,"@type":92},"DocShare","Organization","application/vnd.openxmlformats-officedocument.wordprocessingml.document","2026-09-29","2026-09-08",true,{"@type":98,"interactionType":99,"userInteractionCount":76},"InteractionCounter",{"@type":100},"ViewAction",{"@type":102,"mainEntity":103},"FAQPage",[104,110,114],{"name":105,"@type":106,"acceptedAnswer":107},"What HBOT dosing schedule is included in this protocol?","Question",{"text":108,"@type":109},"The protocol includes 60 daily HBOT sessions delivered over about three months, with five sessions per week.","Answer",{"name":111,"@type":106,"acceptedAnswer":112},"What are the key session parameters (pressure, oxygen duration, and air breaks)?",{"text":113,"@type":109},"Each session uses 100% oxygen at 2 ATA for a total of 90 minutes, with defined compression/decompression times and air breaks repeated during the oxygen period to minimize oxygen toxicity risk.",{"name":115,"@type":106,"acceptedAnswer":116},"When were blood samples collected and what were they used to measure?",{"text":117,"@type":109},"Blood samples were collected at baseline, at the 30th and 60th sessions, and 1–2 weeks after the last session to assess whole-blood parameters and analyze telomere length and senescence in peripheral blood mononuclear cells.","https://schema.org",{"og:url":78,"og:type":120,"og:title":59,"og:site_name":91,"og:description":61},"article",{"robots":122,"canonical":78},"index,follow",{"doc_id":124,"site_id":56},219162,1788861828,{"code":4,"msg":5,"data":127},{"doc_id":124,"user_id":128,"nickname":88,"user_avatar":129,"doc_module":9,"category_id":45,"category_name":46,"doc_title":59,"doc_description":61,"doc_content":130,"file_id":131,"file_url":132,"file_type":133,"file_size":134,"view_count":76,"is_deleted":4,"is_public":9,"is_downloadable":9,"audit_status":9,"page_count":135,"language":136,"language_code":57,"site_id":56,"html_lang":57,"table_of_contents":137,"faqs":138,"seo_title":139,"seo_description":61,"update_tm":125,"read_time":140},8796095461610,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","Israel Aging Protocols with HBOT\nFull Study : \u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u0014https://www.aging-us.com/article/202188/text\u0015\nprotocol included:\n60 sessions of 100% oxygen\nat 2 ATA\nincluding three (3) air breaks during each session to utilize the hyperoxic hypoxic paradox and minimize the risk of oxygen toxicity\n100% oxygen by mask at 2ATA for 90 minutes with 5-minute air break every 20 minute\nThe protocol comprised of 60 daily sessions, five sessions per week within a three-month period\nTreatment Synopsis:\nTOTAL of 60 Days, 5 sessions per week\n30 daily HBOT sessions\n30 day break with no HBOT sessions\nNOTE: Make up days can be used during 30 day break\n30 daily HBOT sessions\nTreatment concluded\n100% O2 with Mask\n2 ATA\n90 Minutes\nCompression/decompression rate: 3.3 feet per minute\n7.5 minutes allotted for compression\n20 minutes on O2\n5 minute air break\n20 minutes on O2\n5 minute air break\n20 minute on O2\n5 minute air break\n7.5 minutes allotted for decompression\n> Total 90 minutes\nDuring the treatment (as defined in trial), neither lifestyle and diet changes, nor medications adjustments were allowed.\nMedical Testing:\nBlood samples (See study for FULL blood testing parameters)\nWhole blood samples were collected into EDTA tubes using a standard technique, at baseline, at the half-point of the HBOT protocol (30th session), the day of the last HBOT session (60th session) and 1-2 weeks following the last HBOT session.\nReference and Credits:\nResearch Paper \u0013 HYPERLINK \"https://www.aging-us.com/issue/v12i22\" \u0014Volume 12, Issue 22\u0015 pp 22445—22456\nHyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial\nYafit Hachmo\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00141\u0015, \u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u0014*\u0015 , Amir Hadanny\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00142\u0015,\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00143\u0015,\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00144\u0015, \u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u0014*\u0015 , Ramzia Abu Hamed\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00141\u0015 , Malka Daniel-Kotovsky\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00142\u0015 , Merav Catalogna\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00142\u0015 , Gregory Fishlev\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00142\u0015 , Erez Lang\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00142\u0015 , Nir Polak\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00142\u0015 , Keren Doenyas\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00142\u0015 , Mony Friedman\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00142\u0015 , Yonatan Zemel\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00142\u0015 , Yair Bechor\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00142\u0015 , Shai Efrati\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00141\u0015,\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00142\u0015,\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00143\u0015,\u0013 HYPERLINK \"https://www.aging-us.com/article/202188/text\" \u00145\u0015\n1 Research and Development Unit, Shamir Medical Center, Zerifin, Israel\n2 The Sagol Center for Hyperbaric Medicine and Research, Shamir (Assaf-Harofeh) Medical Center, Zerifin, Israel\n3 Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel\n4 Bar Ilan University, Ramat-Gan, Israel\n5 Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv, Israel\n* Equal contribution\nReceived: September 3, 2020       Accepted: October 22, 2020       Published: November 18, 2020\n\u0013 HYPERLINK \"https://doi.org/10.18632/aging.202188\" \u0014https://doi.org/10.18632/aging.202188\u0015\u000bHow to Cite\nCopyright: © 2020 Yafit et al. This is an open access article distributed under the terms of the \u0013 HYPERLINK \"https://creativecommons.org/licenses/by/3.0/\" \u0014Creative Commons Attribution License\u0015 (CC BY 3.0), which permits unrestricted use, distri","cbCaihSfJBOswFjV","https://ap.wps.com/l/cbCaihSfJBOswFjV","docx",568280,23,"English","# Protocol Overview\n## Treatment Synopsis\n## Compression, Oxygen, and Air-Break Schedule\n## Medical Testing\n# Research Context and Findings\n## Study Objective\n## Methods and Measurements\n## Results Summary","[{\"question\":\"What HBOT dosing schedule is included in this protocol?\",\"answer\":\"The protocol includes 60 daily HBOT sessions delivered over about three months, with five sessions per week.\"},{\"question\":\"What are the key session parameters (pressure, oxygen duration, and air breaks)?\",\"answer\":\"Each session uses 100% oxygen at 2 ATA for a total of 90 minutes, with defined compression/decompression times and air breaks repeated during the oxygen period to minimize oxygen toxicity risk.\"},{\"question\":\"When were blood samples collected and what were they used to measure?\",\"answer\":\"Blood samples were collected at baseline, at the 30th and 60th sessions, and 1–2 weeks after the last session to assess whole-blood parameters and analyze telomere length and senescence in peripheral blood mononuclear cells.\"}]","Israel Aging Protocols with HBOT - Full Study - Protocol Included | DOCX",8]