[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-174058-en":3,"doc-seo-174058-105":30,"detail-sidebar-cat-1-en-105":92},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":11,"category_id":12,"category_name":13,"doc_title":14,"doc_description":15,"doc_content":16,"file_id":17,"file_url":18,"file_type":19,"file_size":20,"view_count":4,"is_deleted":4,"is_public":11,"is_downloadable":11,"audit_status":11,"page_count":21,"language":22,"language_code":23,"site_id":24,"html_lang":23,"table_of_contents":25,"faqs":26,"seo_title":27,"seo_description":15,"update_tm":28,"read_time":29},174058,687208528416,"Cipher","https://ap-avatar.wpscdn.com/davatar_9964176cb1d06d4a9deccf72a44ae3dc",1,11,"Presentations","Harmonisation of Endocrine Dynamic Testing - Working group manual","Harmonisation of Endocrine Dynamic Testing (HEDT) provides a joint, freely available laboratory guide for endocrinologists and biochemists to standardize endocrine dynamic test practice. The content functions as guidance only and requires verification and adaptation to local procedures, including patient consent, sample type, and the specific test set naming used by each site. Queries can be directed to the chair of the HEDT working party, while a separate paediatric endocrine dynamic testing protocol is being developed with the HEDT-P group.","Harmonisation of Endocrine Dynamic Testing (HEDT)\nThis manual is a joint initiative from ESA/AACB/RCPA and is freely available as a resource for Endocrinologists and Biochemists. Information provided is a guide only and needs to be verified and modified according to local procedures (e.g. patient consent, sample type, name of test set). Queries can be directed to the chair of the HEDT working party. A separate paediatric endocrine dynamic testing protocol is in progress with the HDET-P working party.\n\u000f\n\u0003Table of Contents\n\u0013 TOC \\o \"1-3\" \\h \\z \\u \u0014\u0013 HYPERLINK \\l \"_Toc524996739\" \u0014HEDT Working Group Members:\t\u0013 PAGEREF _Toc524996739 \\h \u00144\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996740\" \u0014Endocrine Analyte Reporting Unit and Sample Tube\t\u0013 PAGEREF _Toc524996740 \\h \u00145\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996741\" \u00141\tAdrenal\t\u0013 PAGEREF _Toc524996741 \\h \u00148\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996742\" \u00141.1\tSHORT SYNACTHEN TEST\t\u0013 PAGEREF _Toc524996742 \\h \u00148\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996743\" \u00141.2\tPrimary aldosteronism investigation\t\u0013 PAGEREF _Toc524996743 \\h \u001411\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996744\" \u00141.3\tsaline suppression TEST\t\u0013 PAGEREF _Toc524996744 \\h \u001413\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996745\" \u00141.4\tFLUDROCORTISONE suppression TEST\t\u0013 PAGEREF _Toc524996745 \\h \u001415\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996746\" \u00141.5\tOral sodium loading TEST\t\u0013 PAGEREF _Toc524996746 \\h \u001417\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996747\" \u00141.6\tadrenal venous sampling\t\u0013 PAGEREF _Toc524996747 \\h \u001418\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996748\" \u00142\tCushing Overview\t\u0013 PAGEREF _Toc524996748 \\h \u001422\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996749\" \u00142.1\tOVERNIGHT DEXAMETHASONE SUPPRESSION TEST (1 mg DST)\t\u0013 PAGEREF _Toc524996749 \\h \u001423\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996750\" \u00142.2\tLATE NIGHT SALIVARY CORTISOL\t\u0013 PAGEREF _Toc524996750 \\h \u001424\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996751\" \u00142.3\t24 HOUR URINARY FREE CORTISOL (UFC)\t\u0013 PAGEREF _Toc524996751 \\h \u001425\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996752\" \u00142.4\t2-DAY LOW DOSE DEXAMETHASONE SUPPRESSION TEST (LDDST)\t\u0013 PAGEREF _Toc524996752 \\h \u001426\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996753\" \u00142.5\tDEXAMETHASONE-CRH TEST\t\u0013 PAGEREF _Toc524996753 \\h \u001428\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996754\" \u00142.6\tIV 4 mg DEXAMETHASONE SUPPRESSION TEST\t\u0013 PAGEREF _Toc524996754 \\h \u001430\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996755\" \u00142.7\tACTH Dependent Cushing’s Syndrome\t\u0013 PAGEREF _Toc524996755 \\h \u001431\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996756\" \u00142.7.1\tHIGH DOSE DEXAMETHASONE SUPPRESSION TEST (HDDST)\t\u0013 PAGEREF _Toc524996756 \\h \u001431\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996757\" \u00142.7.2\tPERIPHERAL CRH TEST\t\u0013 PAGEREF _Toc524996757 \\h \u001432\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996758\" \u00142.7.3\tBILATERAL INFERIOR PETROSAL SINUS SAMPLING\t\u0013 PAGEREF _Toc524996758 \\h \u001433\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996759\" \u00143\tHypopituitarism\t\u0013 PAGEREF _Toc524996759 \\h \u001436\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996760\" \u00143.1\tINSULIN TOLERANCE TEST\t\u0013 PAGEREF _Toc524996760 \\h \u001436\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996761\" \u00143.2\tOVERNIGHT METYRAPONE TEST\t\u0013 PAGEREF _Toc524996761 \\h \u001440\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996762\" \u00143.3\tGLUCAGON stimulation test\t\u0013 PAGEREF _Toc524996762 \\h \u001442\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996763\" \u00143.4\tgONADOTROPHIN RELEasing hormone stimulation test\t\u0013 PAGEREF _Toc524996763 \\h \u001444\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996764\" \u00144\tAcromegaly\t\u0013 PAGEREF _Toc524996764 \\h \u001446\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996765\" \u00144.1\tGROWTH HORMONE SUPPRESSION TEST\t\u0013 PAGEREF _Toc524996765 \\h \u001446\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996766\" \u00145\tHyperglycaemia investigation\t\u0013 PAGEREF _Toc524996766 \\h \u001448\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996767\" \u00145.1\tORAL GLUCOSE TOLERANCE TEST (OGTT)\t\u0013 PAGEREF _Toc524996767 \\h \u001448\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996768\" \u00146\tHypoglycaemia investigation\t\u0013 PAGEREF _Toc524996768 \\h \u001451\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996769\" \u00146.1\tMIXED MEAL TEST\t\u0013 PAGEREF _Toc524996769 \\h \u001451\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996770\" \u00146.2\tPROLONGED OGTT\t\u0013 PAGEREF _Toc524996770 \\h \u001455\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996771\" \u00146.3\t72 HOUR FAST\t\u0013 PAGEREF _Toc524996771 \\h \u001456\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996772\" \u00146.4\tcalcium stimulation TEST FOR INSULINOMA\t\u0013 PAGEREF _Toc524996772 \\h \u001459\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996773\" \u00147\tDiabetes Insipidus\t\u0013 PAGEREF _Toc524996773 \\h \u001462\u0015\u0015\n\u0013 HYPERLINK \\l \"_Toc524996774\" ","cbCaiekph87ZH3tn","https://ap.wps.com/l/cbCaiekph87ZH3tn","docx",1968559,76,"English","en",105,"# HEDT Working Group Members\n## Endocrine Analyte Reporting Unit and Sample Tube\n## Adrenal\n### Short Synacthen Test","[{\"question\":\"What is the purpose of the HEDT manual?\",\"answer\":\"The HEDT manual standardizes endocrine dynamic testing practices through harmonized guidance for laboratories and clinicians. It is intended to be adapted to local procedures rather than used as an unmodified directive.\"},{\"question\":\"Can the guidance be used directly without modification?\",\"answer\":\"No. Information is provided as a guide only and must be verified and modified according to local procedures, including patient consent, sample type, and the name of the test set.\"},{\"question\":\"Who should be contacted for questions about HEDT?\",\"answer\":\"Queries can be directed to the chair of the HEDT working party. A separate paediatric protocol is also in progress with the HEDT-P working party.\"}]","Harmonisation of Endocrine Dynamic Testing - Working group manual | DOCX",1788309914,27,{"code":4,"msg":31,"data":32},"ok",{"site_id":24,"language":23,"slug":33,"title":14,"keywords":34,"description":15,"schema_data":35,"social_meta":87,"head_meta":89,"extra_data":91,"updated_unix":28},"harmonisation-of-endocrine-dynamic-testing-working-group-manual","",{"@graph":36,"@context":86},[37,54,69],{"@type":38,"itemListElement":39},"BreadcrumbList",[40,44,48,51],{"item":41,"name":42,"@type":43,"position":11},"https://docshare.wps.com","Home","ListItem",{"item":45,"name":46,"@type":43,"position":47},"https://docshare.wps.com/template/","Template",2,{"item":49,"name":13,"@type":43,"position":50},"https://docshare.wps.com/template/presentations/",3,{"item":52,"name":14,"@type":43,"position":53},"https://docshare.wps.com/template/harmonisation-of-endocrine-dynamic-testing-working-group-manual/174058/",4,{"url":52,"name":14,"@type":55,"author":56,"headline":14,"publisher":58,"fileFormat":61,"inLanguage":23,"description":15,"dateModified":62,"datePublished":63,"encodingFormat":61,"isAccessibleForFree":64,"interactionStatistic":65},"DigitalDocument",{"name":9,"@type":57},"Person",{"url":41,"name":59,"@type":60},"DocShare","Organization","application/vnd.openxmlformats-officedocument.wordprocessingml.document","2026-09-03","2026-09-02",true,{"@type":66,"interactionType":67,"userInteractionCount":11},"InteractionCounter",{"@type":68},"ViewAction",{"@type":70,"mainEntity":71},"FAQPage",[72,78,82],{"name":73,"@type":74,"acceptedAnswer":75},"What is the purpose of the HEDT manual?","Question",{"text":76,"@type":77},"The HEDT manual standardizes endocrine dynamic testing practices through harmonized guidance for laboratories and clinicians. It is intended to be adapted to local procedures rather than used as an unmodified directive.","Answer",{"name":79,"@type":74,"acceptedAnswer":80},"Can the guidance be used directly without modification?",{"text":81,"@type":77},"No. Information is provided as a guide only and must be verified and modified according to local procedures, including patient consent, sample type, and the name of the test set.",{"name":83,"@type":74,"acceptedAnswer":84},"Who should be contacted for questions about HEDT?",{"text":85,"@type":77},"Queries can be directed to the chair of the HEDT working party. 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