[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-1-en-105":3,"doc-seo-218684-105":53,"doc-detail-218684-en":127},{"code":4,"msg":5,"data":6},0,"success",[7,14,19,24,29,34,39,44,49],{"id":8,"doc_module":9,"doc_module_name":10,"category_name":11,"show_sort_weight":12,"slug":13},11,1,"Template","Presentations",90,"presentations",{"id":15,"doc_module":9,"doc_module_name":10,"category_name":16,"show_sort_weight":17,"slug":18},12,"Resumes",80,"resumes",{"id":20,"doc_module":9,"doc_module_name":10,"category_name":21,"show_sort_weight":22,"slug":23},14,"Invoices",70,"invoices",{"id":25,"doc_module":9,"doc_module_name":10,"category_name":26,"show_sort_weight":27,"slug":28},15,"Posters",60,"posters",{"id":30,"doc_module":9,"doc_module_name":10,"category_name":31,"show_sort_weight":32,"slug":33},16,"Social Media",50,"social-media",{"id":35,"doc_module":9,"doc_module_name":10,"category_name":36,"show_sort_weight":37,"slug":38},17,"Forms",40,"forms",{"id":40,"doc_module":9,"doc_module_name":10,"category_name":41,"show_sort_weight":42,"slug":43},18,"Letters",30,"letters",{"id":45,"doc_module":9,"doc_module_name":10,"category_name":46,"show_sort_weight":47,"slug":48},21,"Paper Templates",5,"papers-templates",{"id":50,"doc_module":9,"doc_module_name":10,"category_name":51,"show_sort_weight":4,"slug":52},158,"General","general-158",{"code":4,"msg":54,"data":55},"ok",{"site_id":56,"language":57,"slug":58,"title":59,"keywords":60,"description":61,"schema_data":62,"social_meta":120,"head_meta":122,"extra_data":124,"updated_unix":126},105,"en","hallmarks-of-cancer-a-guide-to-the-traits-that-define-tumor-development","Hallmarks of Cancer - A guide to the traits that define tumor development","","Presentation on the 10 key traits shared by most cancers, explaining how these capabilities enable tumors to begin, grow, survive, and spread. Each trait is contrasted between cancer cells and normal cells, covering proliferative signaling, evasion of growth suppression, resistance to cell death, replicative immortality, angiogenesis, invasion and metastasis, energy metabolism changes, immune evasion, genome instability and mutation, and tumor-promoting inflammation. Includes prompts to explore the newer hallmarks proposed in 2022.",{"@graph":63,"@context":119},[64,80,102],{"@type":65,"itemListElement":66},"BreadcrumbList",[67,71,74,77],{"item":68,"name":69,"@type":70,"position":9},"https://docshare.wps.com","Home","ListItem",{"item":72,"name":10,"@type":70,"position":73},"https://docshare.wps.com/template/",2,{"item":75,"name":11,"@type":70,"position":76},"https://docshare.wps.com/template/presentations/",3,{"item":78,"name":59,"@type":70,"position":79},"https://docshare.wps.com/template/hallmarks-of-cancer-a-guide-to-the-traits-that-define-tumor-development/218684/",4,{"url":78,"name":59,"@type":81,"image":82,"author":87,"headline":59,"publisher":90,"fileFormat":93,"inLanguage":57,"description":61,"dateModified":94,"datePublished":95,"encodingFormat":93,"isAccessibleForFree":96,"interactionStatistic":97},"DigitalDocument",{"url":83,"@type":84,"width":85,"height":86},"https://docshare.wps.com/thumbnails/hallmarks-of-cancer-a-guide-to-the-traits-that-define-tumor-development/218684.png","ImageObject",442,249,{"name":88,"@type":89},"Miles","Person",{"url":68,"name":91,"@type":92},"DocShare","Organization","application/vnd.openxmlformats-officedocument.presentationml.presentation","2026-10-30","2026-09-08",true,{"@type":98,"interactionType":99,"userInteractionCount":101},"InteractionCounter",{"@type":100},"ViewAction",8,{"@type":103,"mainEntity":104},"FAQPage",[105,111,115],{"name":106,"@type":107,"acceptedAnswer":108},"What does the presentation mean by the “10 key traits of cancer”?","Question",{"text":109,"@type":110},"Over decades of research, scientists identified 10 traits that most cancers share. These traits help explain how cancer begins, grows, survives, and spreads.","Answer",{"name":112,"@type":107,"acceptedAnswer":113},"How do cancer cells sustain proliferative signaling?",{"text":114,"@type":110},"Cancer cells can create their own growth signals or keep them permanently “switched on,” rather than dividing only when external signals are received.",{"name":116,"@type":107,"acceptedAnswer":117},"How does genome instability and mutation help cancer evolve?",{"text":118,"@type":110},"By losing DNA repair systems, cancer cells accumulate mutations that help them evolve and survive, strengthening their ability to adapt.","https://schema.org",{"og:url":78,"og:type":121,"og:title":59,"og:site_name":91,"og:description":61},"article",{"robots":123,"canonical":78},"index,follow",{"doc_id":125,"site_id":56},218684,1791724726,{"code":4,"msg":5,"data":128},{"doc_id":125,"user_id":129,"nickname":88,"user_avatar":130,"doc_module":9,"category_id":8,"category_name":11,"doc_title":59,"doc_description":61,"doc_content":131,"file_id":132,"file_url":133,"file_type":134,"file_size":135,"view_count":101,"is_deleted":4,"is_public":9,"is_downloadable":9,"audit_status":9,"page_count":9,"language":136,"language_code":57,"site_id":56,"html_lang":57,"table_of_contents":137,"faqs":138,"seo_title":139,"seo_description":61,"update_tm":140,"read_time":4},13056703019404,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","Hallmarks of Cancer\nGENTLE CARE\nWELLNESS CENTER\nA guide to the traits that define tumor development\nREALLYGREATSITE.COM\nSustaining proliferative signaling\nGenome instability and mutation\nAvoiding immune destruction\nTumor-promoting inflammation\nInducing angiogenesis\nResisting cell death\nEnabling replicative immortality\nReprogramming energy metabolism\nEvading growth suppressors\nActivating invasion and metastasis\nThe 10 Key Traits of Cancer\nWhat is it?\nOver decades of research, scientists have identified 10 key traits that most cancers share. They help explain how cancer begins, grows, survives, and spreads.\nUnderstanding these traits gives insight into how cancer works and how treatments can target it.\nSustaining proliferative signaling\nCancer cells\nNormal cells\nOnly divide when they receive external signals (like growth factors) from the body.\nDon’t wait for external signals. They make their own or keep growth signals permanently “switched on.”\nGENTLE CARE\nWELLNESS CENTER\nEvading growth suppressors\nCancer cells\nNormal cells\nUse proteins like p53 or Rb as brakes that stop division when it’s unsafe or unnecessary.\nIgnore or disable these growth-stopping mechanisms, allowing uncontrolled cell division.\nGENTLE CARE\nWELLNESS CENTER\nGENTLE CARE\nWELLNESS CENTER\nResisting cell death\nCancer cells\nNormal cells\nUndergo apoptosis (programmed cell death) if damaged or no longer needed.\nIgnore death signals and keep dividing, even when damaged. They may also switch off the genes that trigger apoptosis.\nGENTLE CARE\nWELLNESS CENTER\nEnabling replicative immortality\nCancer cells\nNormal cells\nCan only divide a limited number of times.\nTheir telomeres (chromosome ends) shorten with each division.\nActivate telomerase, an enzyme that rebuilds telomeres, allowing endless cell division.\nGENTLE CARE\nWELLNESS CENTER\nInducing angiogenesis\nCancer cells\nNormal cells\nOnly signal for new blood vessels when needed, like during wound healing.\nRelease signals that force the body to grow new blood vessels to feed the tumor.\nGENTLE CARE\nWELLNESS CENTER\nActivating invasion and metastasis\nCancer cells\nNormal cells\nStay in their original tissue. Strong cell-to-cell connections keep them in place.\nBreak away, invade nearby tissue, and travel through the body to form new tumors.\nReprogramming energy metabolism\nCancer cells\nNormal cells\nUse aerobic respiration in the mitochondria to make energy efficiently (ATP).\nPrefer glycolysis — a less efficient process that helps them grow quickly by creating building blocks for new cells.\nGENTLE CARE\nWELLNESS CENTER\nAvoiding immune destruction\nCancer cells\nNormal cells\nAbnormal or infected cells are detected and destroyed by the immune system.\nDevelop ways to hide from the immune system by suppressing danger signals or disabling immune cells.\nGENTLE CARE\nWELLNESS CENTER\nGENTLE CARE\nWELLNESS CENTER\nGenome instability and mutation\nCancer cells\nNormal cells\nHave strict systems that check and repair DNA to keep the genome stable.\nLose these repair systems, leading to mutations that help them evolve and survive.\nGENTLE CARE\nWELLNESS CENTER\nTumor-promoting inflammation\nCancer cells\nNormal cells\nInflammation is a temporary response to injury or infection and stops once healing is complete.\nUse chronic (long-term) inflammation to access growth signals and attract blood vessels, supporting tumor growth.\nGENTLE CARE\nWELLNESS CENTER\nSustaining proliferative signaling\nRead about the newer hallmarks proposed in 2022.\nChoose two to highlight:\nList their names\nBriefly explain one in your own words\nDescribe how it helps cancer grow or spread\nFonts\nDesign Elements / Icons\nColors\nThis presentation template\nuses the following free fonts:\nYou can find these fonts online too.\nDM Sans Bold\nPublic Sans Regular\nTITLES:\nBODY TEXT:\n#F1F1F2\n#BDFF32\n#B0C5F0\n#10163F\n#0530ED\nUse these in your presentation. Delete or hide this page before presenting.\nResource Page\nThis presentation template is free for everyone to use, thanks to the following:\nfor this present","cbCaiiepIuuGpAlA","https://ap.wps.com/l/cbCaiiepIuuGpAlA","pptx",3781068,"English","# The 10 Key Traits of Cancer\n## What is it?\n## Sustaining proliferative signaling\n## Evading growth suppressors\n## Resisting cell death\n## Enabling replicative immortality\n## Inducing angiogenesis\n## Activating invasion and metastasis\n## Reprogramming energy metabolism\n## Avoiding immune destruction\n## Genome instability and mutation\n## Tumor-promoting inflammation\n## Newer hallmarks proposed in 2022","[{\"question\":\"What does the presentation mean by the “10 key traits of cancer”?\",\"answer\":\"Over decades of research, scientists identified 10 traits that most cancers share. These traits help explain how cancer begins, grows, survives, and spreads.\"},{\"question\":\"How do cancer cells sustain proliferative signaling?\",\"answer\":\"Cancer cells can create their own growth signals or keep them permanently “switched on,” rather than dividing only when external signals are received.\"},{\"question\":\"How does genome instability and mutation help cancer evolve?\",\"answer\":\"By losing DNA repair systems, cancer cells accumulate mutations that help them evolve and survive, strengthening their ability to adapt.\"}]","Hallmarks of Cancer - A guide to the traits that define tumor development | PPTX",1788858387]