[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-188063-105":3,"detail-sidebar-cat-1-en-105":81,"doc-detail-188063-en":127},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":74,"head_meta":76,"extra_data":78,"updated_unix":80},105,"en","gene-expression-of-nanog-and-nanogp8-in-colorectal-cancer","Gene expression of NANOG and NANOGP8 in colorectal cancer","","This document analyzes the gene expression of NANOG and NANOGP8 in colorectal cancer, presenting data from different quarters (Q1, Q2, Q3, Q4) and highlighting statistically significant differences. The analysis specifically focuses on Q1 versus Q4 comparisons, indicating p-values less than 0.01 for both NANOG and NANOGP8, suggesting a substantial change in gene expression between these periods. Additionally, the document mentions TMB-H, dMMR/MSI-H, and PD-L1 positive statuses, which are important biomarkers in cancer diagnostics and treatment. The visual representations likely include graphs or charts depicting these expression levels and their statistical significance, essential for understanding the molecular landscape of colorectal cancer and potential therapeutic targets. Further investigation into the time-course of gene expression and its correlation with clinical parameters is implied by the data 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is the statistical significance of the difference in NANOG gene expression between Q1 and Q4?","Question",{"text":63,"@type":64},"The difference in NANOG gene expression between Q1 and Q4 is statistically significant, with a p-value less than 0.01.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"What does the document suggest about NANOGP8 gene expression between Q1 and Q4?",{"text":68,"@type":64},"Similar to NANOG, there is a statistically significant difference in NANOGP8 gene expression between Q1 and Q4, with a p-value less than 0.01.",{"name":70,"@type":61,"acceptedAnswer":71},"What tumor characteristics are mentioned in relation to gene expression analysis?",{"text":72,"@type":64},"The document mentions TMB-H (Tumor Mutational Burden-High), dMMR/MSI-H (deficient DNA mismatch repair/microsatellite instability-High), and PD-L1 positive statuses in the context of the gene expression analysis.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},188063,1790049016,{"code":4,"msg":82,"data":83},"success",[84,89,94,99,104,109,114,119,124],{"id":85,"doc_module":22,"doc_module_name":25,"category_name":86,"show_sort_weight":87,"slug":88},11,"Presentations",90,"presentations",{"id":90,"doc_module":22,"doc_module_name":25,"category_name":91,"show_sort_weight":92,"slug":93},12,"Resumes",80,"resumes",{"id":95,"doc_module":22,"doc_module_name":25,"category_name":96,"show_sort_weight":97,"slug":98},14,"Invoices",70,"invoices",{"id":100,"doc_module":22,"doc_module_name":25,"category_name":101,"show_sort_weight":102,"slug":103},15,"Posters",60,"posters",{"id":105,"doc_module":22,"doc_module_name":25,"category_name":106,"show_sort_weight":107,"slug":108},16,"Social 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p\u003C0.01 NANOGP8 |\n| |\n| Q1 vs Q4 p\u003C0.01 |\n| \u003Cbr>Q1 vs Q4 p\u003C0.01 |\n| |\n|  |\n|  |\n|  |","cbCaieWiZYskLPYc","https://ap.wps.com/l/cbCaieWiZYskLPYc","pdf",532340,"English","[{\"question\":\"What is the statistical significance of the difference in NANOG gene expression between Q1 and Q4?\",\"answer\":\"The difference in NANOG gene expression between Q1 and Q4 is statistically significant, with a p-value less than 0.01.\"},{\"question\":\"What does the document suggest about NANOGP8 gene expression between Q1 and Q4?\",\"answer\":\"Similar to NANOG, there is a statistically significant difference in NANOGP8 gene expression between Q1 and Q4, with a p-value less than 0.01.\"},{\"question\":\"What tumor characteristics are mentioned in relation to gene expression analysis?\",\"answer\":\"The document mentions TMB-H (Tumor Mutational Burden-High), dMMR/MSI-H (deficient DNA mismatch repair/microsatellite instability-High), and PD-L1 positive statuses in the context of the gene expression analysis.\"}]","Gene expression of NANOG and NANOGP8 in colorectal cancer | PDF",1788387059]