[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-563731-105":3,"detail-sidebar-cat-1-en-105":74,"doc-detail-563731-en":120},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":67,"head_meta":69,"extra_data":71,"updated_unix":73},105,"en","estradiol-transdermal-patches-mylan-new-zealand-data-sheet","Estradiol Transdermal Patches (Mylan) - New Zealand Data Sheet","","New Zealand data sheet for Estradiol Transdermal Patches (Mylan), presenting product strengths (0.025–0.1 mg/day) and composition details for estradiol delivery. The document specifies pharmaceutical form characteristics by dosage and outlines clinical particulars, including indications for estrogen replacement therapy in menopause and prevention of postmenopausal osteoporosis. It provides dosing and administration guidance: start with the lowest effective dose, adjust based on clinical response, apply every 3–4 days (twice weekly), and rotate application sites, with additional progestogen regimens for women with an intact uterus.",{"@graph":14,"@context":66},[15,34,49],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/template/","Template",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/template/paper-templates/","Paper Templates",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/template/estradiol-transdermal-patches-mylan-new-zealand-data-sheet/563731/",4,{"url":32,"name":10,"@type":35,"author":36,"headline":10,"publisher":39,"fileFormat":42,"inLanguage":8,"description":12,"dateModified":43,"datePublished":43,"encodingFormat":42,"isAccessibleForFree":44,"interactionStatistic":45},"DigitalDocument",{"name":37,"@type":38},"miaandmiso","Person",{"url":19,"name":40,"@type":41},"DocShare","Organization","application/pdf","2026-10-12",true,{"@type":46,"interactionType":47,"userInteractionCount":4},"InteractionCounter",{"@type":48},"ViewAction",{"@type":50,"mainEntity":51},"FAQPage",[52,58,62],{"name":53,"@type":54,"acceptedAnswer":55},"What are the approved indications for Estradiol Transdermal Patches in the data sheet?","Question",{"text":56,"@type":57},"They are indicated for estrogen replacement therapy to treat symptoms of natural or surgically induced menopause, and for prevention of postmenopausal osteoporosis. In women with an intact uterus, estrogen should be supplemented with a progestogen.","Answer",{"name":59,"@type":54,"acceptedAnswer":60},"How should Estradiol Transdermal Patches be dosed and applied?",{"text":61,"@type":57},"Treatment is generally started with the lowest dose and adjusted based on clinical response. The patches should be applied every 3 to 4 days (twice weekly), with maintenance at the lowest effective dose.",{"name":63,"@type":54,"acceptedAnswer":64},"How should the patches be applied and how often should the site be rotated?",{"text":65,"@type":57},"Place the adhesive side on a clean, dry area of the abdomen, avoid applying to the breasts, and replace the patch twice weekly. Rotate the application site and allow at least 1 week between uses of the same site, avoiding oily, damaged, or irritated skin.","https://schema.org",{"og:url":32,"og:type":68,"og:title":10,"og:site_name":40,"og:description":12},"article",{"robots":70,"canonical":32},"index,follow",{"doc_id":72,"site_id":7},563731,1791837945,{"code":4,"msg":75,"data":76},"success",[77,82,87,92,97,102,107,112,116],{"id":78,"doc_module":22,"doc_module_name":25,"category_name":79,"show_sort_weight":80,"slug":81},11,"Presentations",90,"presentations",{"id":83,"doc_module":22,"doc_module_name":25,"category_name":84,"show_sort_weight":85,"slug":86},12,"Resumes",80,"resumes",{"id":88,"doc_module":22,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},14,"Invoices",70,"invoices",{"id":93,"doc_module":22,"doc_module_name":25,"category_name":94,"show_sort_weight":95,"slug":96},15,"Posters",60,"posters",{"id":98,"doc_module":22,"doc_module_name":25,"category_name":99,"show_sort_weight":100,"slug":101},16,"Social Media",50,"social-media",{"id":103,"doc_module":22,"doc_module_name":25,"category_name":104,"show_sort_weight":105,"slug":106},17,"Forms",40,"forms",{"id":108,"doc_module":22,"doc_module_name":25,"category_name":109,"show_sort_weight":110,"slug":111},18,"Letters",30,"letters",{"id":113,"doc_module":22,"doc_module_name":25,"category_name":29,"show_sort_weight":114,"slug":115},21,5,"papers-templates",{"id":117,"doc_module":22,"doc_module_name":25,"category_name":118,"show_sort_weight":4,"slug":119},158,"General","general-158",{"code":4,"msg":75,"data":121},{"doc_id":72,"user_id":122,"nickname":37,"user_avatar":123,"doc_module":22,"category_id":113,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":124,"file_id":125,"file_url":126,"file_type":127,"file_size":128,"view_count":4,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":129,"language":130,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":131,"faqs":132,"seo_title":133,"seo_description":12,"update_tm":73,"read_time":114},7971478544854,"https://ap-avatar.wpscdn.com/davatar_994ba38a5ba835b3df7d355c54d3ed8d","NEW ZEALAND DATA SHEET  \nESTRADIOL TRANSDERMAL PATCHES (MYLAN)  \n\n| 1. Product Name |\n| --- |\n| Estradiol, 0.025 mg/day, 0.05 mg/day, 0.075 mg/day, 0.1 mg/day, Transdermal Patches |\n| 2. Qualitative and Quantitative Composition |\n| Each Estradiol Transdermal Patch contains 0.025 mg/day, 0.05 mg/day, 0.075 mg/day, 0.1 mg/day of estradiol (also known as oestradiol) .\u003Cbr>• The 0.025 mg/day is available as a 2.5 cm2 system containing estradiol, USP hemihydrate equivalent to 0.41 mg of estradiol for nominal delivery of 0.025 mg of estradiol per day.\u003Cbr>• The 0.05 mg/day is available as a 5.0 cm2 system containing estradiol, USP hemihydrate equivalent to 0.82 mg of estradiol for nominal delivery of 0.05 mg of estradiol per day.\u003Cbr>• The 0.075 mg/day is available as a 7.5 cm2 system containing estradiol, USP hemihydrate equivalent to 1.23 mg of estradiol for nominal delivery of 0.075 mg of estradiol per day.\u003Cbr>• The 0.1 mg/day is available as a 10.0 cm2 system containing estradiol, USP hemihydrate equivalent to 1.64 mg of estradiol for nominal delivery of 0.1 mg of estradiol per day.\u003Cbr>For the full list of excipients, see section 6.1. |\n| 3. Pharmaceutical Form |\n| 0.025 mg/day – Each rectangular patch with rounded corners consists of an opaque, white to cream adhesive layer, matte film backing randomly printed with ‘Estradiol 0.025 mg/day’ in brown ink, anda clear release liner. The patch is contained in a square, flat, notched, pouch.\u003Cbr>0.05 mg/day – Each rectangular patch with rounded corners consists of an opaque, white to cream adhesive layer, matte film backing randomly printed with ‘Estradiol 0.05 mg/day’ in brown ink, and a clear release liner. The patch is contained in a square, flat, notched, pouch.\u003Cbr>0.075 mg/day – Each rectangular patch with rounded corners consists of an opaque, white to cream adhesive layer, matte film backing randomly printed with ‘Estradiol 0.075 mg/day’ in brown ink, anda clear release liner. The patch is contained in a square, flat, notched, pouch.\u003Cbr>0.1 mg/day – Each rectangular patch with rounded corners consists of an opaque, white to cream adhesive layer, matte film backing randomly printed with ‘Estradiol 0.1 mg/day’ in brown ink, and a clear release liner. The patch is contained in a square, flat, notched, pouch. |\n| 4. Clinical Particulars |\n\n4.1 Therapeutic indications  \nEstradiol Transdermal Patches are indicated for the following:  \n• Oestrogen (also known as estrogen) replacement therapy for the treatment of the symptoms of natural or surgically induced menopause.  \n• Prevention of postmenopausal osteoporosis (see Dosage and Administration and Warningsand Precautions) .  \nIn women with an intact uterus, oestrogens should always be supplemented by administration of aprogestogen.  \n4.2 Dose and method of administration  \nDose  \nAdults and geriatric patients  \nHormone replacement therapy (HRT) involving either oestrogen-only or oestrogen-progestogen combined therapy should only be continued as long as the benefits outweigh the risks for the individual.  \nEstradiol Transdermal Patches should be applied every 3 to 4 days (i.e. twice weekly) .  \nClimacteric symptoms  \nTreatment should be initiated with the lowest dose. Depending on the clinical response the dose should be adjusted to the woman’s individual needs. If, after three months, there is an insufficient response in the form of alleviated symptoms, the dose should be increased. If symptoms of overdose arise (e.g. tender breasts) the dose must be decreased. Maintenance therapy must always be at the lowest effective dose.  \nPrevention of postmenopausal osteoporosis  \nTreatment should be initiated with the lowest dose. Dose adjustments can be made by using other strengths of Estradiol Transdermal Patches. The lowest effective dose should be used for maintenance therapy.  \nGeneral Instructions  \nEstradiol Transdermal Patches is administered as continuous therapy (uninterrupted application twice weekly) . In women with an intact uterus, ","cbCaio5exQBhxcdy","https://ap.wps.com/l/cbCaio5exQBhxcdy","pdf",199726,13,"English","# Product Name\n# Qualitative and Quantitative Composition\n# Pharmaceutical Form\n# Clinical Particulars\n## Therapeutic Indications\n## Dose and Method of Administration","[{\"question\":\"What are the approved indications for Estradiol Transdermal Patches in the data sheet?\",\"answer\":\"They are indicated for estrogen replacement therapy to treat symptoms of natural or surgically induced menopause, and for prevention of postmenopausal osteoporosis. In women with an intact uterus, estrogen should be supplemented with a progestogen.\"},{\"question\":\"How should Estradiol Transdermal Patches be dosed and applied?\",\"answer\":\"Treatment is generally started with the lowest dose and adjusted based on clinical response. The patches should be applied every 3 to 4 days (twice weekly), with maintenance at the lowest effective dose.\"},{\"question\":\"How should the patches be applied and how often should the site be rotated?\",\"answer\":\"Place the adhesive side on a clean, dry area of the abdomen, avoid applying to the breasts, and replace the patch twice weekly. Rotate the application site and allow at least 1 week between uses of the same site, avoiding oily, damaged, or irritated skin.\"}]","Estradiol Transdermal Patches (Mylan) - New Zealand Data Sheet | PDF"]