[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-241245-105":3,"detail-sidebar-cat-1-en-105":80,"doc-detail-241245-en":126},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":73,"head_meta":75,"extra_data":77,"updated_unix":79},105,"en","anorectal-malformation-etiology-types-and-causes","Anorectal Malformation etiology - Types and causes","","Anorectal malformation etiology summarizes the definition and meaning of anorectal malformation, focusing on causes and the most common types. The content explains what leads to anorectal malformations and outlines key classification patterns relevant for clinical understanding. A range of research citations supports genetic, molecular, and signaling-pathway mechanisms, including autosomal dominant non-syndromic anal atresia and hindgut developmental influences. The emphasis is on linking pathogenesis to observed phenotypic variability.",{"@graph":14,"@context":72},[15,34,55],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/template/","Template",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/template/general/","General",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/template/anorectal-malformation-etiology-types-and-causes/241245/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/anorectal-malformation-etiology-types-and-causes/241245.png","ImageObject",442,249,{"name":42,"@type":43},"Jordan Avery","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-09-24","2026-09-12",true,{"@type":52,"interactionType":53,"userInteractionCount":22},"InteractionCounter",{"@type":54},"ViewAction",{"@type":56,"mainEntity":57},"FAQPage",[58,64,68],{"name":59,"@type":60,"acceptedAnswer":61},"What is the definition of anorectal malformation?","Question",{"text":62,"@type":63},"Anorectal malformation refers to developmental abnormalities involving the anorectal region. The text frames it through its meaning and etiology context.","Answer",{"name":65,"@type":60,"acceptedAnswer":66},"What causes anorectal malformation?",{"text":67,"@type":63},"The document discusses causes related to developmental signaling and genetic mechanisms. It highlights molecular pathway involvement and links to specific etiologic concepts.",{"name":69,"@type":60,"acceptedAnswer":70},"What types of anorectal malformations are most commonly discussed?",{"text":71,"@type":63},"The content focuses on the most common anorectal malformation categories and emphasizes classification into types. It specifically references anal atresia as a key common form.","https://schema.org",{"og:url":32,"og:type":74,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":76,"canonical":32},"index,follow",{"doc_id":78,"site_id":7},241245,1790231098,{"code":4,"msg":81,"data":82},"success",[83,88,93,98,103,108,113,118,123],{"id":84,"doc_module":22,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},11,"Presentations",90,"presentations",{"id":89,"doc_module":22,"doc_module_name":25,"category_name":90,"show_sort_weight":91,"slug":92},12,"Resumes",80,"resumes",{"id":94,"doc_module":22,"doc_module_name":25,"category_name":95,"show_sort_weight":96,"slug":97},14,"Invoices",70,"invoices",{"id":99,"doc_module":22,"doc_module_name":25,"category_name":100,"show_sort_weight":101,"slug":102},15,"Posters",60,"posters",{"id":104,"doc_module":22,"doc_module_name":25,"category_name":105,"show_sort_weight":106,"slug":107},16,"Social Media",50,"social-media",{"id":109,"doc_module":22,"doc_module_name":25,"category_name":110,"show_sort_weight":111,"slug":112},17,"Forms",40,"forms",{"id":114,"doc_module":22,"doc_module_name":25,"category_name":115,"show_sort_weight":116,"slug":117},18,"Letters",30,"letters",{"id":119,"doc_module":22,"doc_module_name":25,"category_name":120,"show_sort_weight":121,"slug":122},21,"Paper Templates",5,"papers-templates",{"id":124,"doc_module":22,"doc_module_name":25,"category_name":29,"show_sort_weight":4,"slug":125},158,"general-158",{"code":4,"msg":81,"data":127},{"doc_id":78,"user_id":128,"nickname":42,"user_avatar":129,"doc_module":22,"category_id":124,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":130,"file_id":131,"file_url":132,"file_type":133,"file_size":134,"view_count":26,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":33,"language":135,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":136,"faqs":137,"seo_title":138,"seo_description":12,"update_tm":139,"read_time":26},1099523882367,"https://ap-avatar.wpscdn.com/davatar_9964176cb1d06d4a9deccf72a44ae3dc","Continue  \nAnorectal malformation etiology  \nMost common anorectal malformation. What causes anorectal malformation. Definition of anorectal malformation. Anorectal malformation meaning. Types of anorectal malformations.  \nJ Pediatr Endocrinol Metab 24(7¢ÃÂÂ8): 585¢ÃÂÂ586PubMedà  Google Scholarà  Schramm C, Draaken M, Tewes G et al (2011) Autosomal-dominant non-syndromic anal atresia: sequencing of candidate genes, array-based molecular karyotyping, and review of the literature. Am J Med Genet A 143A(10): 1087¢ÃÂÂ1090CASà  PubMedà  Google Scholarà  Sudo Y, Numakura C, Abe A et al (2010) Phenotypic variability in a family with Townes-Brocks syndrome. J Pediatr Surg 42(7): 1266¢ÃÂÂ1270PubMedà  Google Scholarà  Page 2 This article is in the 1st percentile (ranked 192, 301st) of the 230,697 tracked articles of a similar age in all journals and the 1st percentile (ranked 14th) of the 19 tracked articles of a similar age in Pediatric Surgery International View more on Altmetric Altmetric calculates a score based on the online attention an article receives. J Pediatr Surg 33(2): 194¢ÃÂÂ197CASà  PubMedà  Google Scholarà  Lynch SA, Bond PM, Copp AJ et al (1995) A gene for autosomal dominant sacral agenesis maps to the holoprosencephaly region at 7q36. Development 125(15):2791¢ÃÂÂ2801CASà  PubMedà  Google Scholarà  Mo R, Kim JH, Zhang J et al (2001) Anorectal malformations caused by defects in sonic hedgehog signaling. Pediatrics 71(5):815¢ÃÂÂ820CASà  PubMedà  Google Scholarà  Garcia-Barcelo MM, Wong KK, Lui VC et al (2008) Identification of a HOXD13 mutation in a VACTERL patient. Pediatr Surg Int 24(8):893¢ÃÂÂ897PubMedà  Google Scholarà  Tsuda T, Iwai N, Deguchi E et al (2011) PCSK5 and GDF11 expression in the hindgut region of mouse embryos with anorectal malformations. J Pediatr Surg 49(9): 1400¢ÃÂÂ1404PubMedà  Google Scholarà  Mullor JL, Dahmane N, Sun T et al (2001) Wnt signals are targets and mediators of Gli function. J Med Genet 34(6):441¢ÃÂÂ446PubMed Centralà  CASà  PubMedà  Google Scholarà  Van Maldergem L, Siitonen HA (2006) Revisiting the craniosynostosis-radial ray hypoplasia association: Baller-Gerold syndrome caused by mutations in the RECQL4 sotiefed ed ocsir o e socignºÃfitna sotnemacideM )8002( la te aP ittimoR ,MC lehcsurD ,CT retraC elgooG od ralohcS ¬â ¢ÃdeMbuP sac1161 \" ¬â ¢Ã 1061 :) 51( 013 amaJ .UTE alep sotsopxe siatef sotar son otovdnih od otnemivlovnesed on o£Ãsserpxe gohegdeH cinoS )6002( la te T elaH , S yelsaeB ,P nadnà ralohcS ¬â ¢ÃdeMbuP ¬â ¢Ã saC324 \" ¬â ¢Ã 904 :) 5( 57 teneG nilC .otnemivlovnesed ed otorb od gninrettap o e otnemicserc o rargetni arap kcabdeef ed otiucric e o£Ã§Ãazilanis ed atacsac amu ed s©Ãvarta mega 4-FGF o e gohegdeH cinoS O )4991( la te lR nosnhoJ ,EC nosleN ,E refuaL elgooG od ralohcs ©Â à dembuP \" ¬â ¢Ã s¢ÃsaC66 \" ¬â ¢Ã 35 : ) 1( 242 etiveD .22 onamuh omossomorc o arap socinºÃ somin ´Ãna AND ed serodacram 53 ed lanoiger o£Ã§Ãazilacol e otnemalosI ) 1991( la te B regnilleS ,dimreDcM ,lM fraduB o £Â ÃraduB elgooG od deMbuP ¬â ¢Ã saC701 \" ¬â ¢Ã 101 :) 1( 5 teneG deM J uoS .odaton res arap opmet siam marevit sele euqrop otla siam mautnop etnemlareg sogitna siam sogitrA .anihC an lev¡Ãrufrepmi sun¢Ã edocsir e ocil³Ãf odic¡Ã ed o£Ã§Ãatnemelpus ) 1002( la te A ronesalliV-aerroC , S iL ,fM sreyM acignà dembup5041 \" ¬â ¢Ã 0041 :) 7( 64 GRUS megartaidepJ .siatinegoru e sovitsegid sotart sod siamret setrap sad esenªÃgofrom a erbos 31-dxoh e 31-axoH seµÃ§Ãatum sad seneg sod megasod ad setnedneped sotiefe sO ) 7991( la te V boluarF ,C niamaR ed,X toraW °Â ralohcS elgooG od deMbuP »ÂsaC462 \" ¬â ¢Ã 062 :)3( 22 teneG taN .acig³Ãloite edadienegoreteh aus ed aicnªÃdive :oriecardiv ed o£Ã§Ãaicossa ad lanoicalupop odutse mU )3891( la te F grebneerG ,FJ oredroC ,JM yruohK ¢ÃralohcS elgooG od dembup155 \" ¬â ¢Ã 055 :)8( 55 teneG muHJ .siatcerona seµÃ§Ãamroflam san )BRNDE( atebaniletodne ed rotpecer od saneg setnairav ed o£Ã§ÃaicossA ) 7002( GM lhaaZ ,WS ¬â ¢Ãralohcs ¬â ¢ÃdeMbuP »","cbCaitDUn1jHo57C","https://ap.wps.com/l/cbCaitDUn1jHo57C","pdf",363057,"English","# Anorectal malformation etiology\n## Definition and meaning\n## Causes of anorectal malformation\n## Types of anorectal malformations\n## Related research findings","[{\"question\":\"What is the definition of anorectal malformation?\",\"answer\":\"Anorectal malformation refers to developmental abnormalities involving the anorectal region. The text frames it through its meaning and etiology context.\"},{\"question\":\"What causes anorectal malformation?\",\"answer\":\"The document discusses causes related to developmental signaling and genetic mechanisms. It highlights molecular pathway involvement and links to specific etiologic concepts.\"},{\"question\":\"What types of anorectal malformations are most commonly discussed?\",\"answer\":\"The content focuses on the most common anorectal malformation categories and emphasizes classification into types. It specifically references anal atresia as a key common form.\"}]","Anorectal Malformation etiology - Types and causes | PDF",1789172225]